Publications by Greta Limoni | EPFL Graph Search

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The establishment of neuronal circuits requires neurons to develop and maintain appropriate connections with cellular partners in and out the central nervous system. These phenomena include elaboration of dendritic arborization and formation of synaptic co ...

The decline of motor ability is a hallmark feature of aging and is accompanied by degeneration of motor synaptic terminals. Consistent with this, Drosophila motor synapses undergo characteristic age -dependent structural fragmentation co -incident with dim ...

Alteration of the levels, localization or post-translational processing of the microtubule associated protein Tau is associated with many neurodegenerative disorders. Here we develop adult-onset models for human Tau (hTau) toxicity in Drosophila that enabl ...

Neural differentiation, synaptic transmission, and action potential propagation depend on membrane sphingolipids, whose metabolism is tightly regulated. Mutations in the ceramide transporter CERT (CERT1), which is involved in sphingolipid biosynthesis, are ...

Greta Limoni

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Modelling and Refining Neuronal Circuits with Guidance Cues: Involvement of Semaphorins

Trio preserves motor synapses and prolongs motor ability during aging

Retromer deficiency in Tauopathy models enhances the truncation and toxicity of Tau

CERT1 mutations perturb human development by disrupting sphingolipid homeostasis