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Esther Amstad

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Related publications (100)

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Biocompatible Amphiphilic Hydrogel–Solid Dimer Particles as Colloidal Surfactants

Esther Amstad

Emulsions of two immiscible liquids can slowly coalesce over time when stabilized by surfactant molecules. Pickering emulsions stabilized by colloidal particles can be much more stable. Here, we fabricate biocompatible amphiphilic dimer particles using a h ...

2017

Localized Ionic Reinforcement of Double Network Granular Hydrogels

Esther Amstad, Alexandra Thoma

Nature produces soft materials with fascinating combinations of mechanical properties. For example, the mussel byssus embodies a combination of stiffness and toughness, a feature that is unmatched by synthetic hydrogels. Key to enabling these excellent mec ...

Wiley-V C H Verlag Gmbh2024

Control of Buckling of Colloidal Supraparticles

Esther Amstad, Gaia De Angelis

The properties of clusters of colloidal particles, often termed supraparticles, are determined by the arrangement of the primary particles. Therefore, controlling the structure formation process is of key importance. While buckled morphologies can result f ...

Wiley2025

Tuning the Incorporation of Magnesium into Calcite during Its Crystallization from Additive-Free Aqueous Solution

Esther Amstad, Huachuan Du

Under ambient conditions, marine organisms are able to synthesize a variety of functional materials, ranging from eye lenses to protective shells through the meticulous control over magnesium incorporation into calcite during its crystallization. The mecha ...

AMER CHEMICAL SOC2019

Microfluidic Fabrication of Capsule Sensor Platform with Double-Shell Structure

Esther Amstad

Metal nanoparticles are frequently employed for the colorimetric detection of specific target molecules using an aggregation-induced shift of the localized surface plasmon resonance. However, metal nanoparticles dispersed in bulk solutions are prone to be ...

WILEY-V C H VERLAG GMBH2019

4D printing of Metal-Reinforced double network granular hydrogels

Esther Amstad, Josephine Anna Eleanor Hughes, Matteo Hirsch, Qinghua Guan

Recent developments in soft actuation demand for resilient, responsive materials with locally varying compositions that are sufficiently stiff to exhibit significant actuation forces. Hydrogels are inherently responsive to certain stimuli. Yet, they typica ...

2023

Amorphous CaCO3: Influence of the Formation Time on Its Degree of Hydration and Stability

Francesco Stellacci, Esther Amstad, Huachuan Du, Mathias Steinacher, Anna Murello

Calcium carbonate (CaCO3) is one of the most abundant biominerals that is prevalent in rocks and often used as a structural material in marine animals. Many of these natural CaCO3-based materials display excellent mechanical properties that are difficult t ...

2018

Devices and methods for forming relatively monodisperse droplets

Esther Amstad

Devices and methods for dividing droplets are generally described. In some embodiments, an article may comprise a fluidic channel comprising an array of obstructions. In certain embodiments, the arrangement of obstructions in the array may affect the flow ...

2014

Cross-talk between emulsion drops: how are hydrophilic reagents transported across oil phases?

Bart Deplancke, Esther Amstad, Antoine Claude Jean Vian, Marjan Biocanin, Gianluca Nicolas Etienne

Emulsion drops are frequently used as vessels, for example, to conduct biochemical reactions in small volumes or to perform screening assays at high throughputs while consuming minimal sample volumes. These applications typically require drops that do not ...

2018

Reducing the shell thickness of double emulsions using microfluidics

Esther Amstad, Antoine Claude Jean Vian

Double emulsion drops are well-suited templates to produce capsules whose dimensions can be conveniently tuned by adjusting those of the drops. To closely control the release kinetics of encapsulants, the composition and thickness of the capsule shell must ...

Springer Verlag2016

Simplified Drop-seq workflow with minimized bead loss using a bead capture and processing microfluidic chip

Bart Deplancke, Esther Amstad, Riccardo Dainese, Johannes Julius Bues, Marjan Biocanin

Single-cell RNA-sequencing (scRNA-seq) has revolutionized biomedical research by enabling the in-depth analysis of cell-to-cell heterogeneity of tissues with unprecedented resolution. One of the catalyzing technologies is single cell droplet microfluidics, ...

2019

Single emulsion drops for photocatalytic water splitting as a membrane-free approach to product separation

Sophia Haussener, Esther Amstad, Gaia De Angelis, Swarnava Nandy, Sangram Ashok Savant

The coevolution of hydrogen and oxygen during photocatalytic water splitting presents a challenge for efficient product separation. Here, we demonstrate membrane-free, drop-based photocatalytic water splitting with inherent product separation and competiti ...

2023

Stabilization of the Amorphous Structure of Spray-Dried Drug Nanoparticles

Esther Amstad

The bioavailability of hydrophobic drugs strongly increases if they are formulated as amorphous materials because the solubility of the amorphous phase is much higher than that of the crystal. Moreover, the stability of these particles against crystallizat ...

Amer Chemical Soc2016

Influence of the Degree of Swelling on the Stiffness and Toughness of Microgel-Reinforced Hydrogels

Esther Amstad, John Martin Kolinski, Michael David Kessler, Tianyu Yuan

The stiffness and toughness of conventional hydrogels decrease with increasing degree of swelling. This behavior makes the stiffness-toughness compromise inherent to hydrogels even more limiting for fully swollen ones, especially for load-bearing applicati ...

WILEY-V C H VERLAG GMBH2023

Black Lipid Membranes: Challenges in Simultaneous Quantitative Characterization by Electrophysiology and Fluorescence Microscopy

Esther Amstad

Horizontal black lipid membranes (BLMs) enable optical microscopy to be combined with the electrophysiological measurements for studying ion channels, peptide pores, and ionophores. However, a careful literature review reveals that simultaneous fluorescenc ...

AMER CHEMICAL SOC2019

Microfluidics of binary liquid mixtures with temperature-dependent miscibility

Esther Amstad, Stefan Guldin

Liquid-liquid microfluidic systems rely on the intricate control over the fluid properties of either miscible or immiscible mixtures. Herein, we report on the use of partially miscible binary liquid mixtures that lend their microfluidic properties from a h ...

ROYAL SOC CHEMISTRY2020

The Investigation of Flory-Huggins Interaction Parameters for Amorphous Solid Dispersion Across the Entire Temperature and Composition Range

Esther Amstad

Amorphous solid dispersion (ASD) is one of the most promising enabling formulations featuring significant water solubility and bioavailability enhancements for biopharmaceutical classification system (BCS) class II and IV drugs. An accurate thermodynamic u ...

2019

Tailored Double Emulsions Made Simple

Esther Amstad

Double emulsions, such as water-in-oil-in-water droplets, are important material platforms for conducting fundamental research and for technological applications. To date, well-defined double-emulsion droplets consisting of a single water core and a thin o ...

Wiley-V C H Verlag Gmbh2021

Rheological Properties of Ionically Crosslinked Viscoelastic 2D Films vs. Corresponding 3D Bulk Hydrogels

Esther Amstad, Gaia De Angelis

Ionically crosslinked hydrogels containing metal coordination motifs have piqued the interest of researchers in recent decades due to their self-healing and adhesive properties. In particular, catechol-functionalized bulk hydrogels have received a lot of a ...

AMER CHEMICAL SOC2023

Electrostatically Reinforced Double Network Granular Hydrogels

Esther Amstad, John Martin Kolinski, Tianyu Yuan, Chenzhuo Li

Rapid advances in biomedical applications and soft robotics demand load-bearing soft materials that can be processed into complex 3D shapes. Direct ink writing (DIW) enables the fabrication of customizable shapes with locally varying compositions. Hydrogel ...

WILEY2025