Publications by Georg Fantner | EPFL Graph Search

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Cancer cells enriched in cholesterol in their plasma membrane impair T-cell-mediated cytotoxicity, which can be augmented by stiffening the cancer cells via cholesterol depletion, as shown in mouse models of adoptive T-cell immunotherapy. Malignant transfo ...

NOVELTY - The scanning method involves generating data signal using a sensor. The first component based on a motion in a first direction of an actuator configured to provide motion between a sample and a probe in the first direction, the first direction su ...

High-resolution live-cell imaging is necessary to study complex biological phenomena. Modern fluorescence microscopy methods are increasingly combined with complementary, label-free techniques to put the fluorescence information into the cellular context. ...

How molecular-level understanding of the crystal growth mechanisms and their relation to lattice bonds informs the rational design of crystals with desired shapes and properties has remained elusive. Here we employ theophylline crystals and drive them into ...

Centrioles are evolutionarily conserved multi-protein organelles essential for forming cilia and centrosomes. Centriole biogenesis begins with self-assembly of SAS-6 proteins into 9-fold symmetrical ring polymers, which then stack into a cartwheel that sca ...

The membrane attack complex (MAC) is a hetero-oligomeric protein assembly that kills pathogens by perforating their cell envelopes. The MAC is formed by sequential assembly of soluble complement proteins C5b, C6, C7, C8 and C9, but little is known about th ...

The bacterial cell envelope is essential for viability, the environmental gatekeeper and first line of defense against external stresses. For most bacteria, the envelope biosynthesis is also the site of action of some of the most important groups of antibi ...

A novel method to design data-driven, fixed-structure controllers with H2 and H∞ performance objectives is presented. The control design problem is transformed into a convex optimization problem with linear matrix inequality constraints, which can be solve ...

Time-lapse light microscopy combined with in vitro neuronal cultures has provided a significant contribution to the field of Developmental Neuroscience. The establishment of the neuronal polarity, i.e., formation of axons and dendrites, key structures resp ...

Increasing the scanning speed in Atomic Force Microscopy (AFM) relies on improving the tracking performance in the vertical direction of motion. The lightly damped resonances of piezo-actuators utilized in AFM nano-positioning stages hinder the maximum ach ...

High-speed atomic force microscopy has proven to be a valuable tool for the study of biomolecular systems at the nanoscale. Expanding its application to larger biological specimens such as membranes or cells has, however, proven difficult, often requiring ...

In this study, we employed traditional methods and deep learning models to improve resolution and quality of low-resolution AFM images made under standard ambient scanning. Both traditional methods and deep learning models were benchmarked and quantified r ...

Understanding hierarchical self-assembly of biological structures requires real time measurement of the self-assembly process over a broad range of length- and timescales. The success of high-speed atomic force microscopy (HS-AFM) in imaging small scale mo ...

In this paper, we present a new architecture for analog amplitude demodulation in high-speed atomic force microscopy (AFM) applications. It features single-cycle capabilities and the possibility to work with elevated cantilever resonance frequencies up to ...

Multifrequency atomic force microscopy imaging has been recently demonstrated as a powerful technique for quickly obtaining information about the mechanical properties of a sample. Combining this development with recent gains in imaging speed through small ...

NOVELTY - The test probe (100) is inserted through periosteum and/or soft tissue on a bone, such that the test probe contacts the bone. The test probe is inserted multiple times into same location of the bone, to create one or more microscopic fractures in ...

Mechanisms to control cell division are essential for cell proliferation and survival. Bacterial cell growth and division require the coordinated activity of peptidoglycan synthases and hydrolytic enzymes to maintain mechanical integrity of the cell wall. ...

Microcantilevers are popular transducers thanks to their simple design and a high sensitivity. In many applications, the cantilevers need to be actuated, either to induce a controlled deflection or to excite the resonance. This can be achieved with integra ...

Dynamic atomic force microscopy (AFM) modes that operate at frequencies far away from the resonance frequency of the cantilever (off-resonance tapping (ORT) modes) can provide high-resolution imaging of a wide range of sample types, including biological sa ...

Hexagonal boron nitride (hBN) has emerged as a promising material platform for nanophotonics and quantum sensing, hosting optically active defects with exceptional properties such as high brightness and large spectral tuning. However, precise control over ...

Georg Fantner

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Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy

Method for scanning sample involves providing compensatory signal to actuator after generating compensatory signal on first component of data signal generated by sensor

Correlative 3D microscopy of single cells using super-resolution and scanning ion-conductance microscopy

Lattice bond chains administer kink anisotropy and inform strategies of theophylline crystal self-healing

Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly

Single-molecule kinetics of pore assembly by the membrane attack complex

Scratching the Surface: Bacterial Cell Envelopes at the Nanoscale

Data-Driven Controller Design for Atomic-Force Microscopy

Label-Free Long-Term Methods for Live Cell Imaging of Neurons: New Opportunities

Data-driven control in atomic force microscopy using a genetic algorithm

Studying biological membranes with extended range high-speed atomic force microscopy

Deep learning for enhancement of low-resolution and noisy scanning probe microscopy images

Large‐Range HS‐AFM Imaging of DNA Self‐Assembly through In Situ Data‐Driven Control

An analog high-speed single-cycle lock-in amplifier for next generation AFM experiments

High-frequency multimodal atomic force microscopy

Bone fracture risk assessing method involves inserting test probe through periosteum and soft tissue on bone, so as to evaluate resistance of bone to microscopic fracture

Overlapping and essential roles for molecular and mechanical mechanisms in mycobacterial cell division

Fabrication of fluid-compatible trilayer cantilevers with integrated piezoelectric actuators

Enhanced feedback performance in off-resonance AFM modes through pulse train sampling

Engineering Optically Active Defects in Hexagonal Boron Nitride Using Focused Ion Beam and Water