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Irene Taurino

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Related publications (40)

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A wearable electrochemical sensing system for non-invasive monitoring of lithium drug in bipolar disorder

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo

Lithium represents the main drug for the treatment of Bipolar Disorder (BD) as it acts as a mood stabilizer. However, because of its narrow therapeutic window, psychiatric patients are obliged to frequent tests in hospital to control their lithium blood co ...

2021

A Differential Electrochemical Readout ASIC with Heterogeneous Integration of Bio-nano Sensors for Amperometric Sensing

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Seyedeh Sara Ghoreishizadeh

A Monolithic biosensing platform is presented for miniaturized amperometric electrochemical sensing in CMOS. The system consists of a fully-integrated current readout circuit for differential current measurement as well as on-die sensors developed by growi ...

2017

Mixed gold and platinum nanostructured layers for all-solid-state ion sensors

Giovanni De Micheli, Sandro Carrara, Danilo Demarchi, Irene Taurino, Francesca Criscuolo

The great interest in portable and wearable monitoring systems has promoted in recent years a major expansion of all-solid-state Ion-Selective Electrodes (ISEs). Nanostructured Solid-Contacts (SCs) have shown a promising potential in order to eliminate the ...

IEEE2018

Study on the bio-functionalization of memristive nanowires for optimum memristive biosensors

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Ioulia Tzouvadaki

Semiconductor nanowires are emerging as promising building blocks for biosensors enabling direct electrical detection of various biomolecules. In this framework, two-terminal Schottky-barrier silicon (Si) nanowire arrays that exhibit memristive electrical ...

Royal Society of Chemistry2016

Electrochemical nanostructured biosensors: carbon nanotubes versus conductive and semi-conductive nanoparticles

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Nima Aliakbarinodehi, Gianluca Piccinini

The aim of this work was to demonstrate that various types of nanostructures provide different gains in terms of sensitivity or detection limit albeit providing the same gain in terms of increased area. Commercial screen printed electrodes (SPEs) were func ...

De Gruyter Open Ltd2015

A Current-Mode Potentiostat for Multi-Target Detection Tested with Different Lactate Biosensors

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Seyedeh Sara Ghoreishizadeh

Real-time and multi-target detection by wireless implantable devices is of increasing interest for chronic patients. In this work, electrode sharing is proposed to minimize the size of the implantable device when several three-electrode-based sensing sites ...

2012

Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators

Sandro Carrara, Danilo Demarchi, Irene Taurino

Google Glass is a recently designed wearable device capable of displaying information in a smartphone-like hands-free format by wireless communication. The Glass also provides convenient control over remote devices, primarily enabled by voice recognition c ...

Nature Research2016

Platinum nanopetal-based potassium sensors for acute cell death monitoring

Giovanni De Micheli, Sandro Carrara, Irene Taurino

Growing interest in the role of ions as cell death regulators has led to the consideration of K+, which plays a major role in events such as necrosis, apoptosis and osmotic shock. These mechanisms induce effluxes of K+, which can be m ...

RSC Publishing2016

Direct growth of nanotubes and graphene nanoflowers on electrochemical platinum electrodes

Giovanni De Micheli, László Forró, Sandro Carrara, Arnaud Magrez, Irene Taurino, Federico Matteini

Multi-walled carbon nanotubes and graphene nanoflowers were grown by a catalytic chemical vapor deposition process on metal surfaces. Electrodeposition was used as a versatile technique to obtain three different iron catalyst coatings on platinum microelec ...

2013

Wireless Monitoring in Intensive Care Units by a 3D-Printed System with Embedded Electronics

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Stradolini, Danilo Demarchi, Stefano Riario

The design, realization, and preliminary test of a portable wireless system for measuring key metabolites (e.g., glucose, lactate, calcium, potassium, etc..) in intensive cure monitoring is presented. The system is composed by a 3D-Printed case, which incl ...

2015

Fully Integrated Biochip Platforms for Advanced Healthcare

Giovanni De Micheli, Sandro Carrara, Catherine Dehollain, Irene Taurino, Camilla Baj-Rossi, Andrea Cavallini, Jacopo Olivo, Seyedeh Sara Ghoreishizadeh, Wayne Burleson

Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers. Continuous monitoring ...

Mdpi Ag2012

Highly-stable Li + ion-selective electrodes based on noble metal nanostructured layers as solid-contacts

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Stradolini, Francesca Criscuolo

Nowadays the development of stable and highly efficient Solid-Contact Ion-Selective Electrodes (SC-ISEs) attracts much attention in the research community because of the great expansion of portable analytical devices. In this work, we present highly stable ...

2018

Wearable multifunctional sweat-sensing system for efficient healthcare monitoring

Simone Aiassa, Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo, Nicolò Oliva, Mandresy Ivan Ny Hanitra

Despite the huge expansion in recent years of sweat sensing and wearable technologies, several challenges are still open, including poor sample collection, separate sampling and analysis, low multi-sensing capabilities and materials toxicity. In this work, ...

Elsevier2020

Performance of Carbon Nano-Scale Allotropes in Detecting Midazolam and Paracetamol in Undiluted Human Serum

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Stradolini, Ioulia Tzouvadaki, Nima Aliakbarinodehi, Sattar Akbari Nakhjavani

Nano-materials are highly exploited to enhance sensing performance of electrochemical electrodes by increasing the Electro-Active Surface Area (EASA). In this work, an analytical calculation of the deposited EASA is presented and experimentally validated b ...

2018

Comparative study of three lactate oxidases from Aerococcus viridans for biosensing applications

Giovanni De Micheli, Sandro Carrara, Irene Taurino

A comparison between engineered and commercially available L-lactate oxidases from Aerococcus viridans was conducted for biosensing applications. Enzymes were adsorbed onto the surfaces of graphite electrodes modified with multi-walled carbon nanotubes. Th ...

Elsevier2013

Wireless Monitoring of Endogenous and Exogenous Biomolecules on an Android Interface

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Camilla Baj-Rossi, Francesca Stradolini, Cristina Boero, Grégoire Casimir Joseph Surrel, Stefano Riario

Monitoring patients in intensive care units is generally expensive and time consuming. A prompter medical intervention for those critical patients is a key factor for their safety. Therefore, a system that offers immediate visualization of the monitored da ...

Institute of Electrical and Electronics Engineers2016

Direct and selective synthesis of a wide range of carbon nanomaterials by CVD at CMOS compatible temperatures

Giovanni De Micheli, László Forró, Sandro Carrara, Arnaud Magrez, Irene Taurino

Biosensors benefit from specific nano- to monitor human metabolites [1], [2]. Moreover, small structuration of the active bio-interface layer. In this electrodes allow us to design many sensing sites, each perspective, a wide range of carbon nanomaterials ...

2014

Efficient voltammetric discrimination of free bilirubin from uric acid and ascorbic acid by a CVD nanographite-based microelectrode

Giovanni De Micheli, László Forró, Sandro Carrara, Arnaud Magrez, Irene Taurino

We report a novel electrochemical sensor based on nanographite grown on platinum microelectrodes for the determination of bilirubin in the presence of normal concentrations of albumin. The albumin is a protein with an intrinsic ability to bind the bilirubi ...

Elsevier Science Bv2014

Carbon and Platinum Nanostructured Electrodes on Miniaturized Devices for Biomedical Diagnostics

Irene Taurino

Nowadays, medical devices face several limitations concerning rapid, reliable and simultaneous quantification of a set of ions and metabolites from a micro-nanoliter volume of undiluted samples. The development of minimally-sized devices is, therefore, of ...

EPFL2015

A novel electrochemical sensor for non-invasive monitoring of lithium levels in mood disorders

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo

Lithium is the main drug for the treatment of mood disorders. Due to its narrow therapeutic window, Therapeutic Drug Monitoring (TDM) is a norm during therapy in order to avoid adverse effects. Consequently, patients are obliged to frequent check-ups in ho ...

2018