Anne-Laure Mahul MellierExpertise
Cellular Biology: Cell culture of mammalian cell lines (U2OS, N2a, M17, SH-S5Y5, Cos, HeLa, HEK, MCF7), Astrocytic and neuronal primary cultures (hippocampus, cortex, striatum, midbrain) from P0 mouse or rat pups or from E16-E19 mice embryos, iPSC neuronal cultures (proliferation, passaging, differentiation in iNeurons or iDopaminergic neurons), Cellular transfection (DNA plasmid, siRNA, shRNA), Lentiviruses production and infection of neuronal primary cultures or mammalian cell lines, Samples pre
Quentin BarraudExpertise
Translational neuroscience · Neuromodulation · Spinal cord injury & Parkinson’s disease · Multi-omics (single-cell, spatial transcriptomics, 3D cleared-tissue imaging) · Preclinical platform management
Mission
To develop, coordinate, and supervise the preclinical activities of .NeuroRestore at EPFL, integrating innovative neuromodulation, gene therapy, and multi-omic strategies. To ensure regulatory compliance of all animal work, support scientific teams in experimental design, and build bridges b
Romain GuietExpertise
Development of BioImage Analysis workflows and algorithms to extract quantitative data from microscopy images.BioSample Preparation : in vitro cell, organoid, time-lapse, fixation, staining strategies, actin, mitochondria, fluorescent protein expressionBioImage Acquisition : Widefield, Confocal, Whole Slide Imaging, Super-resolution (SIM, STORM, STED), FRET, FRAP, FLIMBioImage Analysis: Colocalisation analysis, Deconvolution, Time-lapse , Whole Slide ImagingTools & Software: ImageJ/Fiji, QuPath, i
Stéphanie LacourStéphanie P. Lacour holds the Bertarelli Foundation Chair in Neuroprosthetic Technology in the School of Engineering at EPFL and leads the Laboratory for Soft Bioelectronic Interfaces. She received her PhD in Electrical Engineering from INSA de Lyon, France, and completed postdoctoral research at Princeton University and the University of Cambridge. She is the recipient of the 2006 MIT TR35, a University Research Fellowship of the Royal Society, European Research Council ERC Starting and POC Grants, and a SNSF-ERC Consolidator Grant. She was elected a 2015 Young Global Leader by the World Economic Forum.
Katia GalanExpertise
Histology, genomics, cosec and BSO
Elisa OricchioExpertise
Cancer geneticsMouse modelsTherapyStem cellsLymphoma
Teaching & PhD PhD Students Vamsi Krishna Polavarapu, Asli Ece Kasapoglu, Konstantina Georgakopoulou, Eleni Balli Past EPFL PhD Students Maria Christine Donaldson, Elena Battistello, Daniel Pereira Duarte, Frédérica Schyrr, Ruxandra-Andreea Lambuta, Aaron Simone Petruzzella, Jixing Zhong, Justine Epiney Courses Cancer biology I BIO-471 The course covers in detail molecular mechanisms of cancer development with emphasis on cell
Silvestro MiceraShort biographical sketch Silvestro Micera received the University degree (Laurea) in Electrical Engineering from the University of Pisa, in 1996, and the Ph.D. degree in Biomedical Engineering from the Scuola Superiore Sant'Anna, in 2000. From 2000 to 2009, he has been an Assistant Professor of BioRobotics at the Scuola Superiore Sant'Anna where he is now the Head of the Neural Engineering group. In 2007 he was a Visiting Scientist at the Massachusetts Institute of Technology, Cambridge, USA with a Fulbri
Marwan Muhammad Ahmed AbdellahMarwan Abdellah, a self-motivated engineer born in Cairo, Egypt in 1987. He received his B.Sc. and M.Sc. degrees in Biomedical Engieering with distinction with honor from the Systems & Biomedical Engineering Department (SBME), Faculty of Engineering at Cairo University in 2009 and 2012 respectively. After graduation, he worked as a Research Engineer at IBE Technologies's R&D Department in a 4D ultrasound machines project. Then he moved to work as an Associate Software Engineer at the Biomedical Department in Symbyo Technologies. Afterwards, he joined the Multimedia Laboratory in the Swiss Federal Institute of Technology, Lausanne (EPFL) to conduct a research on H.264 & Reconfigurable Video Coding. Currently, he is working as a Scentific Visualization Engineer in the Blue Brain Project led by Prof. Henery Markram in the Brain Mind Institute at the Swiss Federal Institute of Technology, Lausanne (EPFL). Along with his professional career, Abdellah worked as an instructor at NILES (National Institute of Laser Enhanced Science) in Cairo University. He taught two courses in the areas of Computer Graphics and High Performance Computing. He focused in his M.Sc. thesis research on implementing high performance volume rendering techniques for large scale medical data on heterogeneous platforms. He succeeded in constructing a high performance Fourier Volume Render running entirely on CUDA-enable GPUs. Among his research intersets are High Perfromance Computing, Heterogenous Comuting, Visualization, Scalable Rendering, Computer Graphics & Modelling, Medical Image Processing, Video Processing & Reconfigurable Video Coding, Abdellah has been awarded a graphics card from NVIDIA during attending a workshop in High Performance Computing at the Intenational Center of Theoritical Physics (ICTP) in Trieste, Italy. His graduation project was honored by ITIDA and Egyptian Ministres of Telecommunications & Higher Education during a celebration organized by ITIDA in March 2010.
Grégoire CourtineGrégoire Courtine was originally trained in Mathematics and Physics, but received his PhD degree in Experimental Medicine from the University of Pavia, Italy, and the INSERM Plasticity and Motricity, in France, in 2003. From 2004-2007, he held a Post-doctoral Fellow position at the Brain Research Institute, University of California at Los Angeles (UCLA) under the supervision of Dr. Reggie Edgerton, and was a research associate for the Christopher and Dana Reeve Foundation (CDRF). In 2008, he became Assistant Professor at the faculty of Medicine of the University of Zurich where he established his own research laboratory. In 2012, he was nominated Associate Professor at the Swiss Federal Institute of Technology Lausanne (EPFL) where he holds the International paraplegic foundation (IRP) chair in spinal cord repair at the Center for Neuroprosthetics and the Brain Mind Institute. He published several articles proposing radically new approaches for restoring function after spinal cord injury, which were discussed in national and international press extensively. He received numerous honors and awards such as the 2007 UCLA Chancellors award for excellence in post-doctoral research and the 2009 Schellenberg Prize for his innovative research in spinal cord injury awarded by the International Foundation of Research in Paraplegia.
Werner Alfons Hilda Van GeitWerner is the Group Leader of the Cells team within the Simulation Neuroscience Division in Blue Brain.
The goal of his team is to build the single cell models which are the building blocks of the larger network models used in the Blue Brain Project. The first step when building these cell models consists of reconstructing, analysing and artificially recreating neuron morphologies. Next, a biophysically detailed electrical model for the different cell types is built. For the latter the team uses automated parameter optimisation tools like Blue Brain’s open source BluePyOpt tool, but they are also active in extending and developing other Blue Brain software packages related to single cells.
