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Related publications (65)

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Compressed sensing (CS) MP2RAGE versus standard MPRAGE: A of derived brain volume measurements

Tobias Kober, Tom Hilbert, Gian Franco Piredda

Purpose: T1 Magnetization Prepared Two Rapid Acquisition Gradient Echo (MP2RAGE) with compress sensing (CS) has been proposed as an improvement of the standard MPRAGE sequence with multiple advantages including reduced acquisition time needed to provide a ...

ELSEVIER SCI LTD2022

Simultaneous 3D acquisition of H-1 MRF and Na-23 MRI

Tom Hilbert

Purpose To develop a 3D MR technique to simultaneously acquire proton multiparametric maps (T-1, T-2, and proton density) and sodium density weighted images over the whole brain. Methods We implemented a 3D stack-of-stars MR pulse sequence which consists o ...

WILEY2022

Value of T-2 Mapping MRI for Prostate Cancer Detection and Classification

Tom Hilbert

Background Currently, multi-parametric prostate MRI (mpMRI) consists of a qualitative T-2, diffusion weighted, and dynamic contrast enhanced imaging. Quantification of T-2 imaging might further standardize PCa detection and support artificial intelligence ...

WILEY2022

Synthetic Contrasts in Musculoskeletal MRI A Review

Tobias Kober, Tom Hilbert

This review summarizes the existing techniques and methods used to generate synthetic contrasts from magnetic resonance imaging data focusing on musculoskeletal magnetic resonance imaging. To that end, the different approaches were categorized into 3 diffe ...

LIPPINCOTT WILLIAMS & WILKINS2023

Normative volumes and relaxation times at 3T during brain development

Tobias Kober, Bénédicte Marie Maréchal, Tom Hilbert, Ricardo Alberto Corredor Jerez, Samuele Caneschi

While research has unveiled and quantified brain markers of abnormal neurodevelopment, clinicians still work with qualitative metrics for MRI brain investigation. The purpose of the current article is to bridge the knowledge gap between case-control cohort ...

Nature Portfolio2024

Automated Quantitative Susceptibility and Morphometry MR Study: Feasibility and Interrelation Between Clinical Score, Lesion Load, Deep Grey Matter and Normal-Appearing White Matter in Multiple Sclerosis

Tobias Kober, Meritxell Bach Cuadra, Bénédicte Marie Maréchal, Tom Hilbert

Lesion load (LL), deep gray matter (DGM) and normal-appearing white matter (NAWM) susceptibility and morphometry may help in monitoring brain changes in multiple sclerosis (MS) patients. We aimed at evaluating the feasibility of a fully automated segmentat ...

2024

Accelerated MP2RAGE imaging using Cartesian phyllotaxis readout and compressed sensing reconstruction

Émilie Priscille Claire Mussard, Jean-Philippe Thiran, Reto Meuli, Tobias Kober, Tom Hilbert

Purpose MP2RAGE T-1-weighted imaging has been shown to be beneficial for various applications, mainly because of its good grey-white matter contrast, its B-1-robustness and ability to derive T(1)maps. Even using parallel imaging, the method requires long a ...

WILEY2020

Magnetization transfer in magnetic resonance fingerprinting

Tobias Kober, Tom Hilbert

Purpose To study the effects of magnetization transfer (MT, in which a semi-solid spin pool interacts with the free pool), in the context of magnetic resonance fingerprinting (MRF). Methods Simulations and phantom experiments were performed to study the im ...

WILEY2020

Compressed sensing with signal averaging for improved sensitivity and motion artifact reduction in fluorine-19 MRI

Tobias Kober, Tom Hilbert, Ruud van Heeswijk, Jérôme Yerly

Fluorine-19 (F-19) MRI of injected perfluorocarbon emulsions (PFCs) allows for the non-invasive quantification of inflammation and cell tracking, but suffers from a low signal-to-noise ratio and extended scan time. To address this limitation, we tested the ...

WILEY2020

MRI T2 Mapping of the Knee Providing Synthetic Morphologic Images: Comparison to Conventional Turbo Spin-Echo MRI

Tobias Kober, Tom Hilbert

Background: Use of a T2 mapping sequence in addition to the conventional knee MRI protocol increases sensitivity to early cartilage lesions but is time consuming. ...

RADIOLOGICAL SOC NORTH AMERICA2019

Fast model-based T-2 mapping using SAR-reduced simultaneous multislice excitation

Jean-Philippe Thiran, Tobias Kober, José Pedro Rebelo Ferreira Marques, Gunnar Krüger, Tom Hilbert

Purpose To obtain whole-brain high-resolution T-2 maps in 2 minutes by combining simultaneous multislice excitation and low-power PINS (power independent of number of slices) refocusing pulses with undersampling and a model-based reconstruction. Methods A ...

WILEY2019

Comparison of 2D simultaneous multi-slice and 3D GRASE readout schemes for pseudo-continuous arterial spin labeling of cerebral perfusion at 3 T

Tobias Kober, Bénédicte Marie Maréchal, Tom Hilbert

Objective In this perfusion magnetic resonance imaging study, the performances of different pseudo-continuous arterial spin labeling (PCASL) sequences were compared: two-dimensional (2D) single-shot readout with simultaneous multislice (SMS), 2D single-sho ...

SPRINGER2021

Comparison of T2 Quantification Strategies in the Abdominal-Pelvic Region for Clinical Use

Tom Hilbert

Objectives The aim of the study was to compare different magnetic resonance imaging (MRI) acquisition strategies appropriate for T2 quantification in the abdominal-pelvic area. The different techniques targeted in the study were chosen according to 2 main ...

LIPPINCOTT WILLIAMS & WILKINS2022

Simulated Half-Fourier Acquisitions Single-shot Turbo Spin Echo (HASTE) of the Fetal Brain: Application to Super-Resolution Reconstruction

Tobias Kober, Meritxell Bach Cuadra, Patric Hagmann, Reto Meuli, Tom Hilbert, Thomas Yu

Accurate characterization of in utero human brain maturation is critical as it involves complex interconnected structural and functional processes that may influence health later in life. Magnetic resonance imaging is a powerful tool complementary to the u ...

SPRINGER INTERNATIONAL PUBLISHING AG2021

Clinical equivalence assessment of T2 synthesized pediatric brain magnetic resonance imaging

Tobias Kober, Tom Hilbert, Jocelyn Philippe

Background and purpose. - Automated synthetic magnetic resonance imaging (MRI) provides qualitative, weighted image contrasts as well as quantitative information from one scan and is well-suited for various applications such as analysis of white matter dis ...

MASSON EDITEUR2019

Tom Hilbert

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Compressed sensing (CS) MP2RAGE versus standard MPRAGE: A of derived brain volume measurements

Simultaneous 3D acquisition of H-1 MRF and Na-23 MRI

Value of T-2 Mapping MRI for Prostate Cancer Detection and Classification

Synthetic Contrasts in Musculoskeletal MRI A Review

Normative volumes and relaxation times at 3T during brain development

Automated Quantitative Susceptibility and Morphometry MR Study: Feasibility and Interrelation Between Clinical Score, Lesion Load, Deep Grey Matter and Normal-Appearing White Matter in Multiple Sclerosis

Accelerated MP2RAGE imaging using Cartesian phyllotaxis readout and compressed sensing reconstruction

Magnetization transfer in magnetic resonance fingerprinting

Compressed sensing with signal averaging for improved sensitivity and motion artifact reduction in fluorine-19 MRI

MRI T2 Mapping of the Knee Providing Synthetic Morphologic Images: Comparison to Conventional Turbo Spin-Echo MRI

Fast model-based T-2 mapping using SAR-reduced simultaneous multislice excitation

Comparison of 2D simultaneous multi-slice and 3D GRASE readout schemes for pseudo-continuous arterial spin labeling of cerebral perfusion at 3 T

Comparison of T2 Quantification Strategies in the Abdominal-Pelvic Region for Clinical Use

Simulated Half-Fourier Acquisitions Single-shot Turbo Spin Echo (HASTE) of the Fetal Brain: Application to Super-Resolution Reconstruction

Clinical equivalence assessment of T2 synthesized pediatric brain magnetic resonance imaging

Periventricular gradients of T-1 z-scores correlate with disability in early multiple sclerosis

Deep multiple sclerosis lesion phenotyping using multimodal quantitative MRI

Towards better characterization of spinal cord pathology in early stages of multiple sclerosis using T1 mapping

First evidence on the utility of T-1 mapping of the optic nerve to investigate differences between MS and NMOSD

Personalized pathology maps to quantify diffuse and focal brain damage