Livan Bladimir Alonso Sarduy

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We studied the flocculation mechanism at the molecular level by determining the atomic structures of N-Flo1p and N-Lg-Flo1p in complex with their ligands. We show that they have similar ligand binding mechanisms but distinct carbohydrate specificities and ...

Recently, atomic force microscope (AFM) manufacturers have begun producing instruments specifically designed to image biological specimens. In most instances, they are integrated with an inverted optical microscope, which permits concurrent optical and AFM ...

The aim of this thesis was to explore the topoisomerase-DNA interactions using atomic force microscopy (AFM) in a liquid environment. Firstly, we present a programmable microcontroller-driven injection system for the exchange of an imaging medium while usi ...

The antigen-presenting cell-expressed CD40 is implied in the regulation of counteractive immune responses such as induction of pro-inflammatory and anti-inflammatory cytokines interleukin (IL)-12 and IL-10, respectively. The mechanism of this duality in CD ...

Cancer is a major health issue that absorbs the attention of a large part of the biomedical research. Intercalating agents bind to DNA molecules and can inhibit their synthesis and transcription; thus, they are increasingly used as drugs to fight cancer. I ...

Interaction of the atomic force microscopy (AFM) tip with the sample can be invasive for soft samples. Frequency Modulation (FM) AFM is gentler because it allows scanning in the non-contact regime where only attractive forces exist between the tip and the ...

We present a programmable microcontroller-driven injection system for the exchange of imaging medium during atomic force microscopy. Using this low-noise system, high-resolution imaging can be performed during this process of injection without disturbance. ...

AFM; DNA topology; Human topoisomerase II; Binding geometry; Time-lapse imaging; Protein–DNA interaction ...

The widespread misuse of drugs has increased the number of multiresistant bacteria1, and this means that tools that can rapidly detect and characterize bacterial response to antibiotics are much needed in the management of infections. Various techniques, s ...

Motion detector comprising a flexible support (1,5) adapted to hold at least one object (6-9), a sensor (4) for measuring the displacement of said support (1) and processing means for differentiating the fluctuations of said support (1) from those induced ...

Livan Bladimir Alonso Sarduy

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Molecular Mechanism of Flocculation Self-Recognition in Yeast and Its Role in Mating and Survival

A universal fluid cell for the imaging of biological specimens in the atomic force microscope

Study of Topoisomerase-DNA Interaction Using Atomic Force Microscopy

Differential peptide binding to CD40 evokes counteractive responses

Time-Lapse AFM Imaging of DNA Conformational Changes Induced by Daunorubicin

FM-AFM constant height imaging and force curves: high resolution study of DNA-tip interactions

Microcontroller-driven fluid-injection system for atomic force microscopy

Human topoisomerase II-DNA interaction study by using atomic force microscopy

Rapid detection of bacterial resistance to antibiotics using AFM cantilevers as nanomechanical sensors

Differential peptide binding to CD40 evokes counteractive responses (vol 73, pg 465, 2012)

Nanoscale motion detector