Cristina Ramona Cudalbu Moldovan

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Creatine de fi ciency syndromes (CDS), caused by mutations in GATM (AGAT), GAMT , and SLC6A8 , mainly affect the central nervous system (CNS). CDS show brain creatine (Cr) de fi ciency, intellectual disability with severe speech delay, behavioral troubles, ...

The recent developments in high magnetic field (13) C magnetic resonance spectroscopy with improved localization and shimming techniques have led to important gains in sensitivity and spectral resolution of (13) C in vivo spectra in the rodent brain, enabl ...

Accurate assessment of the macromolecule contributions in short echo-time proton MRS spectra is important for a reliable quantification of the neurochemical profile. The aim of the present study was to assess two approaches based on using LCModel, which ta ...

1H MRS in the cerebellum was used to study the effect of 2-octynohydroxamic acid (2-octynoHA) treatment on the brain of bile duct ligated (BDL) rats (type C hepatic encephalopathy). The study included four groups of rats: negative control group (rats recei ...

The translation of MRS to clinical practice has been impeded by the lack of technical standardization. There are multiple methods of acquisition, post-processing, and analysis whose details greatly impact the interpretation of the results. These details ar ...

OBJECT: To determine the single spin-echo T 2 relaxation times of uncoupled and J-coupled metabolites in rat brain in vivo at 14.1 T and to compare these results with those previously obtained at 9.4 T. MATERIALS AND METHODS: Measurements were performed on ...

Cristina Ramona Cudalbu Moldovan

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The Beneficial Effect of Oral Cr Supplementation in an Early Childhood Rat Model of Chronic Hepatic Encephalopathy: In Vivo Longitudinal 1H and 31P Magnetic Resonance Spectroscopy Study

Central Nervous System Oxidative Stress interplay with inflammation in a rat model of Type C Hepatic Encephalopathy - brothers in arms?

Brain Regional Susceptibility to Oxidative Stress in a Rat Model of Chronic Hepatic Encephalopathy: In-Vivo 1H MRS, Ex-Vivo ESR Spectroscopy and Histology Findings

Assessment Of Cerebral Osmotic Regulation In A Rat Model Of Biliary Cirrhosis Using MR Spectroscopy

Rescue of myocytes and locomotion through AAV2/9-2YF intracisternal gene therapy in a rat model of creatine transporter deficiency

Differences in CNS metabolism between pups and adults in an animal model of biliary cirrhosis: longitudinal, non-invasive in vivo study

Which prior knowledge? Quantification of in vivo brain (13) C MR spectra following (13) C glucose infusion using AMARES

In vivo longitudinal 1H Spectroscopic Imaging and Diffusion Tensor Imaging studies at 9.4T in a rat model of chronic liver failure

Comparison of two approaches to model the macromolecule spectrum for the quantification of short TE H-1 MRS spectra

Age Dependence of Neurometabolic Changes in a Rat Pup Model of Type C Hepatic Encephalopathy

Neurochemical profile differentiation of glioma induced by cancer stem cells expressing WIF1: a 1H-MRS longitudinal study at 14.1T

Neurometabolic profiles of bile duct ligated rats after the treatment with an urease inhibitor – 1H MRS dataset

Glutamine synthesis rate in the hyperammonaemic rat brain using simultaneous localized in vivo H-1 and N-15 MRS

Editorial for the special issue on Brain Biochemistry in Liver Disease

Hippocampal and Cerebellar Astrocytes Morphological Alterations in a Rat Model of Chronic Hepatic Encephalopathy

Impact of the prior knowledge on the quantification of in vivo 13C spectra using two different algorithms: LCModel and AMARES

Minimum Reporting Standards for in vivo Magnetic Resonance Spectroscopy (MRSinMRS): Experts' consensus recommendations

MEASUREMENT OF GLUTAMINE SYNTHESIS RATE IN THE HYPERAMMONAEMIC RAT BRAIN USING IN VIVO 1H AND 15N MRS

In vivo Magnetic Resonance Spectroscopy (MRS) studies of brain metabolism during ammonia infusion

Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain