Bénédicte Marie Maréchal

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Dementing neurodegenerative disorders have more and more prominent public health implications with the most frequent cause being the currently non reversible Alzheimer's Disease (AD). However, over the past 15 years, an abundant literature has demonstrated ...

Background: There is increasing evidence that children or young adults having acquired liver disease in childhood display neurocognitive impairment which may become more apparent as they grow older. The molecular, cellular and morphological underpinnings o ...

Background Acute methanol poisoning leads to optic neuropathy and necrotic lesions of basal ganglia (BG) and subcortical white matter. Survivors of methanol poisoning exhibit long-term executive and memory deficits. Associations between brain volumetry par ...

Objective: Pathology in multiple sclerosis is not homogenously distributed. Recently, it has been shown that structures adjacent to CSF are more severely affected. A gradient of brain tissue involvement was shown with more severe pathology in periventricul ...

Purpose: Although clinical 7T MRI offers various advantages compared to lower field strengths, achieving spatially uniform flip angle distributions remains a challenge. Sampling Perfection with Application optimized Contrast using different flip angle Evol ...

Purpose: Studies at 3T have shown that T-1 relaxometry enables characterization of brain tissues at the single-subject level by comparing individual physical properties to a normative atlas. In this work, an atlas of normative T-1 values at 7T is introduce ...

Background: Small-vessel disease (SVD) plays a crucial role in cardiac and brain ischemia, but little is known about potential interrelation between both. We retrospectively evaluated 370 patients, aiming at assessing the interrelation between cardiac and ...

With the rise of open data, identifiability of individuals based on 3D renderings obtained from routine structural magnetic resonance imaging (MRI) scans of the head has become a growing privacy concern. To protect subject privacy, several algorithms have ...

BackgroundTo assess the performance of plasma neurofilament light (NfL) and phosphorylated tau 181 (p-tau181) to inform about cerebral Alzheimer's disease (AD) pathology and predict clinical progression in a memory clinic setting.MethodsPlasma NfL and p-ta ...

The relation of white matter hyperintense lesions to episodic memory impairment in patients with Parkinson's disease (PD) is still controversial. We aimed at evaluating the relation between white matter hyperintense lesions and episodic memory decline in p ...

Neurofilament light chain (NfL) has been demonstrated to correlate with multiple sclerosis disease severity as well as treatment response. Nevertheless, additional serum biomarkers are still needed to better differentiate disease activity from disease prog ...

Background: Age-related white matter lesions (WML) are common, impact neuronal connectivity, and affect motor function and cognition. In addition to pathological nigrostriatal losses, WML are also common co morbidities in Parkinson's disease (PD) that affe ...

The translational potential of MR-based connectivity modelling is limited by the need for advanced diffusion imaging, which is not part of clinical protocols for many diseases. In addition, where diffusion data is available, brain connectivity analyses rel ...

Fully automated machine learning methods based on structural magnetic resonance imaging data can assist radiologists in the diagnosis of Alzheimer's disease (AD). These algorithms require large data sets to learn the separation of subjects with and without ...

Background Early infratentorial and focal spinal cord lesions on magnetic resonance imaging (MRI) are associated with a higher risk of long-term disability in patients with multiple sclerosis (MS). The role of diffuse spinal cord lesions remains less under ...

Background: Basal ganglia lesions are typical findings on magnetic resonance imaging (MRI) of the brain in survivors of acute methanol poisoning. However, no data are available on the association between the magnitude of damaged brain regions, serum concen ...

Background: Amnestic syndrome of the hippocampal type (ASHT) in Memory Clinics is a presentation common to Alzheimer's disease (AD). However, ASHT can be found in other neurodegenerative disorders. Objective: To compare brain morphometry including hippocam ...

Objectives This study introduced a tailored MP2RAGE-based brain acquisition for a comprehensive assessment of the normal maturing brain. Methods Seventy normal patients (35 girls and 35 boys) from 1 to 16 years of age were recruited within a prospective mo ...

Objective In brain volume assessment with MR imaging, it is of interest to know the effects of the pulse sequence and software used, to determine whether they provide equivalent data. The aim of this study was to compare cross-sectional volumes of subcorti ...

In patients with parkinsonian syndromes, and particularly during the early stages of the clinical disease, differentiating between idiopathic Parkinson's disease and progressive supranuclear palsy is challenging. Imaging plays an important role in early di ...

Bénédicte Marie Maréchal

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Toward Reliable MR-Based Brain Structure Morphometry : Importance of Rigorous Quality Control

High field brain proton magnetic resonance spectroscopy and volumetry in children with chronic, compensated liver disease-A pilot study

Methanol Poisoning as an Acute Toxicological Basal Ganglia Lesion Model: Evidence from Brain Volumetry and Cognition

Periventricular gradient of T1 tissue alterations in multiple sclerosis

Individually optimized dynamic parallel transmit pulses for 3D high‐resolution SPACE imaging at 7T

Submillimeter T-1 atlas for subject-specific abnormality detection at 7T

Interrelation between cardiac and brain small-vessel disease: a pilot quantitative PET and MRI study

Fast refacing of MR images with a generative neural network lowers re-identification risk and preserves volumetric consistency

Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer's disease pathology and clinical disease progression

Episodic memory decline in Parkinson' s disease: relation with white matter hyperintense lesions and influence of quantification method

Serum GFAP in multiple sclerosis: correlation with disease type and MRI markers of disease severity

Clinical correlates of white matter lesions in Parkinson's disease using automated multi-modal segmentation measures

Validating atlas-based lesion disconnectomics in multiple sclerosis: A retrospective multi-centric study

Effects of hardware heterogeneity on the performance of SVM Alzheimer's disease classifier

Brainstem lesions are associated with diffuse spinal cord involvement in early multiple sclerosis

MRI-based brain volumetry and retinal optical coherence tomography as the biomarkers of outcome in acute methanol poisoning

Amnestic Syndrome in Memory Clinics: Similar Morphological Brain Patterns in Older Adults with and without Alzheimer's Disease

Normal volumetric and T1 relaxation time values at 1.5 T in segmented pediatric brain MRI using a MP2RAGE acquisition

Quantitative comparison of subcortical and ventricular volumetry derived from MPRAGE and MP2RAGE images using different brain morphometry software

A method for fast automated assessment of the magnetic resonance parkinsonism index