Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Priscilla TurelliPositions
2005-now: Research associate, Federal School of Life Sciences, Laboratory of Virology and Genetics, Lausanne, Switzerland
2001-2004: Research associate in Pr D. Tronos laboratory, Department of Microbiology, Geneva School of Medicine, Switzerland
1997-2001: Post-doctoral research fellow in Pr D. Tronos laboratory, Department of Microbiology, Geneva School of Medicine, Switzerland
Honors and fellowships
2004: Bristol-Myers Squibb AIDS AWARD
1997-1999: Human Frontier Science Program fellowship
Education
June 1997:
PhD in cellular biology.
Final mark:jury congratulations.
Université de la Méditerranée, France.
June 1993:
Post-graduate diploma in cellular biology and microbiology.
INSERM U372, Marseille-Luminy, université de Provence, France.
June 1992:
Master in cellular biology Specialty: genetic.
Final mark: Best master student of this year.
Université de la Méditerranée, France.
June 1987:
Scientific baccalaureate, France.
Teaching experience
2009-now: phD thesis co-director, School of Life Sciences, Lausanne, Switzerland.
2002: Tutor in virology for medical students, 2nd year, Geneva School of Medicine, Switzerland.
1996-1997: Tutor in molecular biology and biochemistry for under-graduate students,
Université de la Méditerranée, Aix Marseille II, France.
Bruno LemaitrePersonal Webpage
http://brunolemaitre.ch
Personal Webpage http://brunolemaitre.ch
Teaching & PhD PhD Students Blandine Ribotta, Yao Tian, Désirée Popelka, Prince Kumar Sah, Siqi Wang, Kenan Krakovic, Nathan Alexandre Klotz Past EPFL PhD Students Sveta Chakrabarti, Olivier Binggeli, Jeremy Keith Herren, Juan Camilo Paredes Escobar, Alfred Chng, Maroun Bou Sleiman, Jan Paul Dudzic, Mario Gonzalo Garcia Arraez, Claudia Melcarne, Alice Marra, Bianca Marie Petrignani, Mark Austin Hanson, Alexia Laurie Carboni Stewart ColeProfessor Stewart Cole is an international authority in bacterial molecular-genetics and genomics. He has made outstanding contributions in several fields including: bacterial anaerobic electron transport; genome analysis of retroviruses and papillomaviruses; antibiotic resistance mechanisms; and the molecular microbiology of toxigenic clostridia. His studies on isoniazid and multidrug resistance in Mycobacterium tuberculosis, together with his pioneering work on the pathogenicity, evolution and genomics of the tubercle and leprosy bacilli, have made him an undisputed leader in the field of mycobacterial research. The findings of his research are of direct relevance to public health and disease-control in both the developing world and the industrialised nations. He has published over 250 scientific papers and review articles, and holds many patents.
Kristina SchoonjansExpertise
Bile acid signalingNutrient sensingIntermediary metabolismMetabolic disorders
Teaching & PhD PhD Students Adrien Faure Past EPFL PhD Students Pan Xu, Ece Yildiz, Nadia Bresciani, Yu Sun, Francesca Pontanari, Alejandro Alonso Calleja Past EPFL PhD Students as codirector Mitsunori Nomura, Pan Xu, Katyayanee Neopane, Lucie Camille Chanvillard, Jakob Josef Langer, Bilge Sen Elçi Courses General Biology BIOENG-110 The purpose of the course is to provide a general overview of the biolo
Ute KochExpertise
SCIENTIFIC EXPERTISESCurrent Molecular Biology and Cloning, Developmental Biology, Cellular and Molecular Immunology, Lymphocyte Maturation and Lineage Commitment, Thymic Selection, Hematopoietic Stem Cell Biology, Bone Marrow Transplantation, Graft-versus-Host Disease, Skin Transplantation, T Lymphocyte Subset Induction (Th1 - Th2, Cytokine Regulation), Extensive Knowledge in Flow CytometryIT SKILLSMicrosoft-Office: Word, Excel, PowerPoint.File Maker Pro: Database design and management.Flow cytom
Giovanna AmbrosiniCurrent Position Senior Scientist, School of Life Sciences, Bioinformatics Competence Center, école Polythechnique Fédérale de Lausanne, Lausanne.Senior bioinformatician and software engineer with proven experience working in higher education institutions. Solid experience in scientific computing and web design. Proficient in physics and computational genomics, with a focus on high-throughput genomic sequencing data analysis (ChIP-seq, ATAC-seq, RNA-seq, scRNA-seq, and exome sequencing) and other types of
Florence PojerExpertise
MER and Head of Unit - Protein Production and Structure Reseach Core Facility within the Life Sciences School - PTPSP: Expertise in Integrative protein Structural Biology (mainly X-ray Crystallography and Cryo-EM) and production of macromolecules in mammalian and bacterial cells. Innovate4Life team member at SV: i4L supports the next generation of entrepreneurs through education, mentorship, and funding, to translate life sciences discoveries into technologies that benefit society. Education and
Vassily HatzimanikatisDr. Vassily Hatzimanikatis is currently Associate Professor of Chemical Engineering and Bioengineering at Ecole Polytechnique Federale de Lausanne (EPFL), in Lausanne, Switzerland. Vassily received a PhD and an MS in Chemical Engineering from the California Institute of Technology, and his Diploma in Chemical Engineering from the University of Patras, in Greece. After the completion of his doctoral studies, he held a research group leader position at the Swiss Federal Institute of Technology in Zurich (ETHZ), Switzerland. Prior to joining EPFL, Vassily worked for three years in DuPont, Cargill, and Cargill Dow, and he has been assistant professor at Northwestern University, at Illinois, USA.
Vassilys research interests are in the areas of computational systems biology, biotechnology, and complexity. He is associate editor of the journals Biotechnology & Bioengineering, Metabolic Engineering and Integrative Biology, and he serves on the editorial advisory board of the journals Bioprocess and Biosystems Engineering, Journal of Chemical Technology and Biotechnology, and Industrial Biotechnology. He has written over 70 technical publications and he is co-inventor in three patents and patent applications.
Vassily is a fellow of the American Institute for Medical and Biological Engineering (2010), he was a DuPont Young Professor (2001-2004), and he has also received the Jay Bailey Young Investigator Award in Metabolic Engineering (2000), and the ACS Elmar Gaden Award (2011).
Sandra Eloise KjeldsenPositions
2008- : Laborantine (Laboratoire du Pr D. Trono), Laboratoire de virologie et génétique, EPFL, Suisse.
2004-2008: Laborantine (Laboratoire du Pr A. Trumpp), ISREC, Suisse.
2004: Assistante de recherche (Laboratoire du Pr G. Corradin), Institut de Biochimie, Université de Lausanne, Suisse.
Éducation
1999 - 2004:
Diplôme en Biologie (spécialités : Immunologie, Biochimie et Pharmacologie)
Université de Lausanne, Suisse.
Juin 1999:
Baccalauréat Scientifique, France. Cristina Ramona Cudalbu MoldovanCristina Cudalbu obtained her Bachelors of Science degree in Medical Physics in 2002 and Masters of Science degree in Biophysics and Medical Physics in 2003, both from University Babes-Bolyai, Cluj-Napoca, Romania. In 2006 she obtained her PhD degree in Localized Proton MRS and time domain quantification of cerebral metabolites at 7T and 4.7T at University Lyon 1, RMN Laboratory, Villeurbanne, France.In 2007, she joined, as a Scientist, the Laboratory for Functional and Metabolic Imaging at EPFL, where she implemented new acquisition and quantification techniques for in vivo nitrogen, proton and carbon MRS for preclinical studies. Starting 2012, Cristina Cudalbu was appointed as Research Staff Scientist and 9.4T MRI Operational Manager at Centre d’Imagerie Biomédicale (CIBM) at EPFL. She is now developing new research lines at CIBM, being oriented towards new acquisition and quantification techniques for in vivo proton, phosphorous, carbon, nitrogen MRS and fast MRSI, diffusion weighted spectroscopy and brain macromolecules quantification. She is now applying these developments on chronic hepatic encephalopathy, a research area that she developed at CIBM (https://actu.epfl.ch/news/when-liver-disease-affects-the-brain/), and on different collaborative projects with researchers from the five partner institutions of CIBM. Laure MeninExpertise
Mass spectrometryLC-MS / GC-MSBiochemistryProteomicsToxinologyDrug discovery
Teaching & PhD Courses Mass spectrometry, principles and applications CH-728 The goal is to provide students with a complete overview of the principles and key applications of modern mass spectrometry and meet the current practical demand of EPFL researchers to improve structural analsis of molecules. Numerous instrumental aspects of mass spectrometry are described.
Bastien MangeatAddress
Bastien Mangeat, PhDGene Expression Core Facility (GECF)School of Life Sciences EPFL - Station 191015 LausanneSwitzerlandOffice: SV1535
Email for projects submissions and demands
Please use gecf@epfl.ch (one email per project)
Phone (email preferred)
Landline (only internal calls are answered): 37 113Mobile (important/urgent only): 41 79 752 20 86
Teaching & PhD Courses Methods: omics in biomedical research BIOENG-519 High-throughput methodologies broadly called Omics allow to charac Andrea KrappTeaching & PhD Past EPFL PhD Students as codirector Claudia Melcarne Courses Practical - Karthaus Lab BIO-616 Students will learn 1) how organoids can be used in biomedical research 2) How to perform organoid culture 3) How to perform basic genetic manipulations
