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Rolf Gruetter

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Related publications (418)

Direct in vivo measurement of glycine and the neurochemical profile in the rat medulla oblongata

Rolf Gruetter, Giulio Gambarota, Lijing Xin, João Miguel das Neves Duarte

The medulla oblongata (MO) contains a high density of glycinergic synapses and a particularly high concentration of glycine The aims of this study were to measure directly in vivo the neurochemical profile, including glycine, in MO using a spin-echo-based ...

Wiley-Blackwell2010

Imaging glutamine synthesis rates in the hyperammonemic rat brain

Bernard Lanz, Rolf Gruetter, Hanne Frenkel, Cristina Ramona Cudalbu

2010

Investigation of spatial distribution of metabolites in rat brain at elevated plasma glucose levels

Rolf Gruetter, Hanne Frenkel, Cristina Ramona Cudalbu

2010

Feasibility of in vivo N-15 MRS detection of hyperpolarized N-15 labeled choline in rats

Arnaud Comment, Rolf Gruetter, Sami Jannin, Ruud van Heeswijk, Fiodar Kurdzesau, Cristina Ramona Cudalbu

The increase of total choline in tumors has become an important biomarker in cancer diagnosis. Choline and choline metabolites can be measured in vivo and in vitro using multinuclear MRS. Recent in vivo C-13 MRS studies using labeled substrates enhanced vi ...

2010

Effects of Lactoferrin on altered brain metabolism in pup rats after prenatal exposure to Dexamethasone

Rolf Gruetter, Yohan Van de Looij

2010

Localized 31P saturation transfer in rat brain

Yves Pilloud, Rolf Gruetter, Cristina Ramona Cudalbu

2010

Quantification of brain glycogen concentration and turnover through localized C-13 NMR of both the C1 and C6 resonances

Rolf Gruetter, Ruud van Heeswijk, Lijing Xin

We have recently shown that at isotopic steady state C-13 NMR can provide a direct measurement of glycogen concentration changes, but that the turnover of glycogen was not accessible with this protocol. The aim of the present study was to design, implement ...

Wiley-Blackwell2010

In vivo hyperpolarized 89Y studies in a 9.4T animal scanner

Arnaud Comment, Rolf Gruetter, Mor-Miri Mishkovsky, Tian Cheng

2010

Lactoferrin Supplementation Protects Brain Development in Rat Pups Exposed to Prenatal Dexamethasone

Rolf Gruetter, Yohan Van de Looij

Lippincott, Williams & Wilkins2010

Neurochemical profile of the mouse hypothalamus using in vivo1H MRS at 14.1T

Rolf Gruetter, Hongxia Lei, Carole Poitry-Yamate

The hypothalamus plays an essential role in the central nervous system of mammals by among others regulating glucose homeostasis, food intake, temperature, and to some extent blood pressure. Assessments of hypothalamic metabolism using, e.g. 1H MRS in mous ...

Wiley-Blackwell2010

Effects of diffusion time on diffusion tensor derived parameters measured on the rat brain at ultrahigh magnetic field

Nicolas Kunz, Rolf Gruetter, Yohan Van de Looij

2010

BOLD responses to trigeminal nerve stimulation

Carl Petersen, Rolf Gruetter, Nathalie Just

The current study investigates a new model of barrel cortex activation using stimulation of the infraorbital branch of the trigeminal nerve. A robust and reproducible activation of the rat barrel cortex was obtained following trigeminal nerve stimulation. ...

2010

Eddy current effects on a clinical 7T-68 cm bore scanner

Rolf Gruetter, Wietske Van der Zwaag, Gunnar Krüger, Tobias Kober, José Pedro Rebelo Ferreira Marques

Eddy currents induced by switching of magnetic field gradients can lead to distortions in short echo-time spectroscopy or diffusion weighted imaging. In small bore magnets, such as human head-only systems, minimization of eddy current effects is more deman ...

2010

Cerebellar Cortical Layers: In Vivo Visualization with Structural High-Field-Strength MR Imaging

Rolf Gruetter, Wietske Van der Zwaag, Gunnar Krüger, José Pedro Rebelo Ferreira Marques, Cristina Granziera

Purpose: To perform in vivo imaging of the cerebellum with an in-plane resolution of 120 mm to observe its cortical granular and molecular layers by taking advantage of the high signal-to-noise ratio and the increased magnetic susceptibility-related contra ...

2010

Spread spectrum for compressed sensing techniques in magnetic resonance imaging

Jean-Philippe Thiran, Pierre Vandergheynst, Dimitri Nestor Alice Van De Ville, Rolf Gruetter, Yves Wiaux, Gilles Puy

Magnetic resonance imaging (MRI) probes signals through Fourier measurements. Accelerating the acquisition process is of major interest for various MRI applications. The recent theory of compressed sensing shows that sparse or compressible signals may be r ...

IEEE Signal Process. Soc.2010

Scavenging Free Radicals To Preserve Enhancement and Extend Relaxation Times in NMR using Dynamic Nuclear Polarization

Arnaud Comment, Geoffrey Bodenhausen, Sandrine Gerber, Rolf Gruetter, Sami Jannin, Riddhiman Sarkar, Paul Romeo Vasos, Puneet Ahuja, Pascal Miéville, Mor-Miri Mishkovsky

Vitamin C for longer lifetimes: N-oxide radicals that are widely used for dynamic nuclear polarization can be reduced by scavengers such as sodium ascorbate (vitamin C) during the dissolution process, thus diminishing losses of polarization during the tran ...

Wiley-Blackwell2010

RETRACTED: Marker-independent identification of glioma-initiating cells

Rolf Gruetter, Cristina Ramona Cudalbu

Tumor-initiating cells with stem cell properties are believed to sustain the growth of gliomas, but proposed markers such as CD133 cannot be used to identify these cells with sufficient specificity. We report an alternative isolation method purely based on ...

Nature Publishing Group2010

Diffusion-Weighted Spectroscopy: A Novel Approach to Determine Macromolecule Resonances in Short-Echo Time H-1-MRS

Nicolas Kunz, Rolf Gruetter, Cristina Ramona Cudalbu

Quantification of short-echo time proton magnetic resonance spectroscopy results in >18 metabolite concentrations (neurochemical profile). Their quantification accuracy depends on the assessment of the contribution of macromolecule (MM) resonances, previou ...

Wiley-Blackwell2010

Where sound position influences sound object representations: A 7-T fMRI study

Stephanie Clarke, Rolf Gruetter, Wietske Van der Zwaag

Evidence from human and non-human primate studies supports a dual-pathway model of audition, with partially segregated cortical networks for sound recognition and sound localisation, referred to as the What and Where processing streams. In normal subjects, ...

Elsevier2010

In vivo simultaneous measurement of glutamine synthetase and glutamate dehydrogenase activity in the hyperammonemic rat brain using localized 1H and 15N MRS

Yves Pilloud, Bernard Lanz, Rolf Gruetter, Paul Romeo Vasos, Cristina Ramona Cudalbu

2010

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