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François Lazeyras

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Related publications (44)

Connectivity and tissue microstructural alterations in right and left temporal lobe epilepsy revealed by diffusion spectrum imaging

Jean-Philippe Thiran, Nicolas Kunz, François Lazeyras, Alia Lemkaddem, Alessandro Daducci

Focal epilepsy is increasingly recognized as the result of an altered brain network, both on the structural and functional levels and the characterization of these widespread brain alterations is crucial for our understanding of the clinical manifestation ...

2014

Robust T1-Weighted Structural Brain Imaging and Morphometry at 7T Using MP2RAGE

Patric Hagmann, François Lazeyras, Gunnar Krüger, Tobias Kober, José Pedro Rebelo Ferreira Marques, Alexis Roche, Kieran O'Brien

Purpose To suppress the noise, by sacrificing some of the signal homogeneity for numerical stability, in uniform T1 weighted (T1w) images obtained with the magnetization prepared 2 rapid gradient echoes sequence (MP2RAGE) and to compare the clinical utilit ...

Public Library of Science2014

Assessing white matter microstructure of the newborn with multi-shell diffusion MRI and biophysical compartment models

Nicolas Kunz, François Lazeyras, Kieran O'Brien, Hui Zhang

Brain white matter connections have become a focus of major interest with important maturational processes occurring in newborns. To study the complex microstructural developmental changes in-vivo, it is imperative that non-invasive neuroimaging approaches ...

Elsevier2014

Structural Graph Analysis of Left and Right Temporal Lobe Epilepsy using Diffusion Spectrum Imaging

Jean-Philippe Thiran, François Lazeyras, Alia Lemkaddem, Alessandro Daducci

Patients with Temporal Lobe Epilepsy (TLE) suffer from widespread subtle white matter abnormalities and abnormal functional connectivity extending beyond the affected lobe, as revealed by volumetric and functional MRI studies. Diffusion Magnetic Resonance ...

2014

Dielectric pads and low- B1+ adiabatic pulses: Complementary techniques to optimize structural T1w whole-brain MP2RAGE scans at 7 tesla

François Lazeyras, Gunnar Krüger, Tobias Kober, José Pedro Rebelo Ferreira Marques, Kieran O'Brien

Purpose To evaluate the combination of low-B1+ adiabatic pulses and high permittivity (εr ≈ 165) dielectric pads effectiveness to reproducibly improve the inversion efficiency for whole-brain MP2RAGE scans, at ultra-high field. Materials and Methods Two lo ...

Wiley-Blackwell2014

Micro-Structural Brain Alterations in Aviremic HIV+ Patients with Minor Neurocognitive Disorders: A Multi-Contrast Study at High Field

Djalel Eddine Meskaldji, Reto Meuli, François Lazeyras, Gunnar Krüger, Tobias Kober, Cristina Granziera, Alessandro Daducci, Alexis Roche

Objective Mild neurocognitive disorders (MND) affect a subset of HIV+ patients under effective combination antiretroviral therapy (cART). In this study, we used an innovative multi-contrast magnetic resonance imaging (MRI) approach at high-field to assess ...

Public Library of Science2013

Mapping interictal epileptic discharges using mutual information between concurrent EEG and fMRI

Dimitri Nestor Alice Van De Ville, François Lazeyras

Objective: The mapping of haemodynamic changes related to interictal epileptic discharges (IED) in simultaneous electroencephalography (EEG) and functional MRI (fMRI) studies is usually carried out by means of EEG-correlated fMRI analyses where the EEG inf ...

Elsevier2013

Total activation: fMRI deconvolution through spatio-temporal regularization

Dimitri Nestor Alice Van De Ville, François Lazeyras, Fikret Isik Karahanoglu

Confirmatory approaches to fMRI data analysis look for evidence for the presence of pre-defined regressors modeling contributions to the voxel time series, including the BOLD response following neuronal activation. As more complicated questions arise about ...

Elsevier2013

3D Residual Eddy Current Field Characterisation: applied to Diffusion Weighted Magnetic Resonance Imaging

François Lazeyras, Rolf Gruetter, Gunnar Krüger, Alessandro Daducci, Kieran O'Brien

Clinical use of the Stejskal-Tanner diffusion weighted images is hampered by the geometric distortions that result from the large residual 3D eddy current field induced. In this work we aimed to predict, using linear response theory, the residual 3D eddy c ...

Institute of Electrical and Electronics Engineers2013

A simple method to denoise MP2RAGE

François Lazeyras, Rolf Gruetter, Gunnar Krüger, Alexis Roche, Kieran O'Brien

2013

Hyperpolarization of 129Xe by sublimation DNP using photo-activated radical precursors

Arnaud Comment, Christophe Roussel, François Lazeyras, Tim Rolf Eichhorn, Jean-Noël Hyacinthe, Najat Salameh, Andrea Capozzi

2013

High-field diffusion tensor imaging characterization of cerebral white matter injury in lipopolysaccharide-exposed fetal sheep

François Lazeyras, Yohan Van de Looij

BACKGROUND: In gyrencephalic species such as sheep, precise anatomical and microstructural characterization of the consequences of fetal inflammation remains scarce. The goal of this study was to characterize changes in white matter (WM) structure using ad ...

Lippincott, Williams & Wilkins2012

Morphology-driven automatic segmentation of MR images of the neonatal brain

Michel Kocher, François Lazeyras, Laura Ioana Gui, Radoslaw Lisowski

The segmentation of MR images of the neonatal brain is an essential step in the study and evaluation of infant brain development. State-of-the-art methods for adult brain MRI segmentation are not applicable to the neonatal brain, due to large differences i ...

Elsevier Science Bv2012

Patient-specific mean pressure drop in the systemic arterial tree, a comparison between 1-D and 3-D models

Nikolaos Stergiopoulos, Philippe Reymond, François Lazeyras

One-dimensional models of the systemic arterial tree are useful tools for studying wave propagation phenomena, however, their formulation for frictional losses is approximate and often based on solutions for developed flow in straight non-tapered arterial ...

Elsevier2012

Whole-brain structural connectivity in temporal lobe epilepsy: a Diffusion Spectrum Imaging study

Jean-Philippe Thiran, François Lazeyras, Alia Lemkaddem, Alessandra Griffa, Alessandro Daducci

Introduction: Medial Temporal Lobe Epilepsy (mTLE) with hippocampal sclerosis is the most frequent cause of drug-resistant focal epilepsy in adults. These patients suffer from widespread subtle white matter abnormalities and abnormal functional connectivit ...

2012

A multi-center study: Intra-scan and inter-scan variability of Diffusion Spectrum Imaging

Jean-Philippe Thiran, François Lazeyras, Alia Lemkaddem, Gunnar Krüger, Alessandro Daducci, Kieran O'Brien

The objective of this study was to investigate whether it is possible to pool together diffusion spectrum imaging data from four different scanners, located at three different sites. Two of the scanners had identical configuration whereas two did not. To m ...

Elsevier2012

Graph theory to analyse developmental plasticity in connectivity of preterm children

Jean-Philippe Thiran, François Lazeyras, Alessandra Griffa, Elda Fischi Gomez, Alessandro Daducci

2012

Validation of a patient-specific one-dimensional model of the systemic arterial tree

Nikolaos Stergiopoulos, Philippe Reymond, Yvette Bohraus, François Lazeyras

Reymond P, Bohraus Y, Perren F, Lazeyras F, Stergiopulos N. Validation of a patient-specific one-dimensional model of the systemic arterial tree. Am J Physiol Heart Circ Physiol 301: H1173-H1182, 2011. First published May 27, 2011; doi:10.1152/ajpheart.008 ...

2011

Testing the variability of Diffusion Spectrum Imaging (DSI): Inter- and intra-site comparison on "identical" 3T scanners

Jean-Philippe Thiran, Reto Meuli, François Lazeyras, Alia Lemkaddem, Gunnar Krüger, Alessandro Daducci

Multi-center neuroimaging studies have more power than smaller ones to conduct sophisticated studies of basic neuroanatomy and clinical disorders. One important confound of combining images obtained from different scanners is the potential for scanner effe ...

2011

Activelets: Wavelets for sparse representation of hemodynamic responses

Michaël Unser, Dimitri Nestor Alice Van De Ville, François Lazeyras, Ildar Khalidov

We propose a new framework to extract the activity-related component in the BOLD functional magnetic resonance imaging (fMRI) signal. As opposed to traditional fMRI signal analysis techniques, we do not impose any prior knowledge of the event timing. Inste ...

Elsevier2011

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