Publications by Loay Awad | EPFL Graph Search

Related publications (9)

Synthesis of chemical tools to improve water solubility and promote the delivery of salinomycin to cancer cells

Chemotherapy and radiation are unable to eliminate all cancer cells, particularly apoptosis-resistant cancer cells, despite their ability to kill cancer cluster cells. Thus, it is important to identify methods that eliminate all cancer cells in order to pr ...

SPANDIDOS PUBL LTD2020

Rational Design of Indoleamine 2,3-Dioxygenase Inhibitors

Pierre Vogel, Loay Awad

Indoleamine 2,3-dioxygenase (IDO) is an important therapeutic target for the treatment of diseases such as cancer that involve pathological immune escape. We have used the evolutionary docking algorithm EADock to design new inhibitors of this enzyme. First ...

2010

Seasonal and spatial variation in total trihalomethane formation potential in groundwater in Tulkarm and Hebron, Palestine

Loay Awad

Water disinfection using processes such as chlorination is required to kill bacteria and harmful biological components. During chlorination, organic components in water react with chlorine, forming harmful disinfection by-products such as trihalomethanes ( ...

SPRINGER HEIDELBERG2019

A C-Linked Disaccharide Analogue of Thomsen-Friedenreich Epitope Induces a Strong Immune Response in Mice

Pierre Vogel, Loay Awad, Annabelle Gillig, Maria Kolympadi

2012

Silyl methallylsulfinates: efficient and powerful agents for the chemoselective silylation of alcohols, polyols, phenols and carboxylic acids

Pierre Vogel, Loay Awad, Cotinica Craita, Xiaogen Huang

Alcohols, phenols and carboxylic acids are silylated with very good yields in the presence of silyl methallylsulfinates under non- basic conditions and with the formation of volatile co-products. ...

Royal Society of Chemistry2005

C-linked disaccharide analogue of the Thomsen-Friedenreich (T)-epitope alpha-O-conjugated to L-serine

Pierre Vogel, Loay Awad

Condensation of a silylated beta-D-galactopyranosylaldehyde (3) with isolevoglucosenone (4) in the presence of Et(2)AII provided bicyclic enone 5. Subsequent addition of BnNHOMe gave adduct 6, which was converted into 4-O-acetyl-1,6-anhydro-3-C-[ R)1.3,4,5 ...

2005

Chemical strategies for controlling protein folding and elucidating the molecular mechanisms of amyloid formation and toxicity

Hilal Lashuel, Bruno Claude Daniel Fauvet, Loay Awad, Mirva Hejjaoui

It has been more than a century since the first evidence linking the process of amyloid formation to the pathogenesis of Alzheimer's disease. During the last three decades in particular, increasing evidence from various sources (pathology, genetics, cell c ...

Elsevier2012

Improving Water Use Efficiency Using Sensors and Communication System for Irrigation of Greenhouse Tomato in Tulkarm, Palestine

Loay Awad, Clémence Noëlie Marie Ranquet Bouleau

In Palestine, water is one of the major challenges for farmers as water costs are prohibitive and the availability is limited. Innovative technologies and strategies are required improve crop yields, efficient irrigation to produce more nutritious food wit ...

SPRINGER INDIA2022

Synthesis of a C-linked disaccharide analogue of the Thomsen Friedenreich (TF)-epitope a-O-conjugated to L-serine and formation of a cluster as potential anticancer vaccine

Loay Awad

Cell surface glycoproteins and glycolipids are responsible for cellular recognition processes. Vaccination is the procedure whereby the immune system is induced to create antibodies against a foreign molecule involved in disease or viral infection. In many ...

EPFL2005