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Philippe Reymond

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Related publications (31)

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Pressure and Flow Wave Propagation in Patient-Specific Models of the Arterial Tree

Philippe Reymond

Blood flow in the arterial circulation induces hemodynamic forces that play an important role in various forms of vascular diseases. Temporal variation of the wall shear stress seems to play a significant role in atherogenesis and plaque stability. Flow in ...

EPFL2011

Validation of a patient-specific one-dimensional model of the systemic arterial tree

Nikolaos Stergiopoulos, François Lazeyras, Philippe Reymond

Reymond P, Bohraus Y, Perren F, Lazeyras F, Stergiopulos N. Validation of a patient-specific one-dimensional model of the systemic arterial tree. Am J Physiol Heart Circ Physiol 301: H1173-H1182, 2011. First published May 27, 2011; doi:10.1152/ajpheart.008 ...

2011

Validation of a one-dimensional model of the systemic arterial tree

Nikolaos Stergiopoulos, Philippe Reymond, Fabrice Merenda

A distributed model of the human arterial tree including all main systemic arteries coupled to a heart model is developed. The one-dimensional (1-D) form of the momentum and continuity equations is solved numerically to obtain pressures and flows throughou ...

2009

Numerical validation of a new method to assess aortic pulse wave velocity from a single recording of a brachial artery waveform with an occluding cuff

Nikolaos Stergiopoulos, Philippe Reymond, Bram Trachet

Recently a new method has been proposed as a tool to measure arterial pulse wave velocity (PWV), a measure of the stiffness of the large arteries and an emerging parameter used as indicator of clinical cardiovascular risk. The method is based on measuremen ...

Springer Verlag2010

Systolic Hypertension Mechanisms: Effect of Global and Local Proximal Aorta Stiffening on Pulse Pressure

Nikolaos Stergiopoulos, Philippe Reymond

Decrease in arterial compliance leads to an increased pulse pressure, as explained by the Windkessel effect. Pressure waveform is the sum of a forward running and a backward running or reflected pressure wave. When the arterial system stiffens, as a result ...

Springer US2012

Influence of inlet boundary conditions on the local haemodynamics of intracranial aneurysms

Nikolaos Stergiopoulos, Philippe Reymond

Haemodynamics is believed to play an important role in the initiation, growth and rupture of intracranial aneurysms. In this context, computational haemodynamics has been extensively used in an effort to establish correlations between flow variables and cl ...

2009

A coupled hydrodynamic model of the cardiovascular and cerebrospinal fluid system

Nikolaos Stergiopoulos, Philippe Reymond

Martin BA, Reymond P, Novy J, Baledent O, Stergiopulos N. A coupled hydrodynamic model of the cardiovascular and cerebrospinal fluid system. Am J Physiol Heart Circ Physiol 302: H1492-H1509, 2012. First published January 20, 2012; doi: 10.1152/ajpheart.006 ...

2012

Experimental evaluation of direct thromboaspiration efficacy according to the angle of interaction between the aspiration catheter and the clot

Mohamed Bouri, Philippe Reymond

Background Successful direct thromboaspiration (DTA) is related to several factors such as clot consistency, size, and location. It has also been demonstrated recently that the angle of interaction (AOI) formed by the aspiration catheter and the clot is re ...

2021

Generic and patient-specific models of the arterial tree

Nikolaos Stergiopoulos, Philippe Reymond, Orestis Vardoulis

Recent advance in imaging modalities used frequently in clinical routine can provide description of the geometrical and hemodynamical properties of the arterial tree in great detail. The combination of such information with models of blood flow of the arte ...

Springer Netherlands2012

Intracranial Stents Being Modeled as a Porous Medium: Flow Simulation in Stented Cerebral Aneurysms

Nikolaos Stergiopoulos, Philippe Reymond

Intracranial aneurysms may be treated by flow diverters, alternatively to stents and coils combination. Numerical simulation allows the assessment of the complex nature of aneurismal flow. Endovascular devices present a rather dense and fine strut network, ...

Springer US2011

Methodologies to assess blood flow in cerebral aneurysms: Current state of research and perspectives

Nikolaos Stergiopoulos, Mohamed Farhat, Philippe Reymond

With intracranial aneurysms disease bringing a weakened arterial wall segment to initiate, grow and potentially rupture an aneurysm, current understanding of vessel wall biology perceives the disease to follow the path of a dynamic evolution and increasing ...

2009

Computational Hemodynamics in Cerebral Aneurysms: The Effects of Modeled Versus Measured Boundary Conditions

Philippe Reymond

Modeling of flow in intracranial aneurysms (IAs) requires flow information at the model boundaries. In absence of patient-specific measurements, typical or modeled boundary conditions (BCs) are often used. This study investigates the effects of modeled ver ...

2011

Reproducibility of haemodynamical simulations in a subject-specific stented aneurysm model - A report on the Virtual Intracranial Stenting Challenge 2007

Philippe Reymond

This paper presents the results of the Virtual Intracranial Stenting Challenge (VISC) 2007, an international initiative whose aim was to establish the reproducibility of state-of-the-art haemodynamical simulation techniques in subject-specific stented mode ...

2008

Transient Neurovascular Interface for Minimally Invasive Neural Recording and Stimulation

Diego Ghezzi, Philippe Reymond, Laura Ferlauto, Adele Fanelli, Elodie Geneviève Zollinger

Neural interfaces are used to mitigate the burden of traumatic injuries, neurodegenerative diseases, and mental disorders. However, the transient or permanent placement of an interface in close contact with the neural tissue requires invasive surgery, pote ...

Wiley2021

Patient-specific mean pressure drop in the systemic arterial tree, a comparison between 1-D and 3-D models

Nikolaos Stergiopoulos, François Lazeyras, Philippe Reymond

One-dimensional models of the systemic arterial tree are useful tools for studying wave propagation phenomena, however, their formulation for frictional losses is approximate and often based on solutions for developed flow in straight non-tapered arterial ...

Elsevier2012

How Flow Reduction Influences the Intracranial Aneurysm Occlusion: A Prospective 4D Phase-Contrast MRI Study

Mohamed Farhat, Philippe Reymond, Pierre Bouillot

BACKGROUND AND PURPOSE: Flow-diverter stents are widely used for the treatment of wide-neck intracranial aneurysms. Various parameters may influence intracranial aneurysm thrombosis, including the flow reduction induced by flow-diverter stent implantation, ...

American Society of Neuroradiology (ASNR)2019

3D simulation of the aqueous flow in the human eye

Nikolaos Stergiopoulos, Philippe Reymond, Sylvain Roy, Orestis Vardoulis, Adan Villamarin

Glaucoma results in an increase in the resistance of the aqueous humor outflow, which in turn leads to an increase of the intraocular pressure (IOP). Several treatments are proposed to reduce and stabilize the IOP that include medications, filtering surger ...

Elsevier Sci Ltd2012

Near-wall hemodynamic parameters quantification in in vitro intracranial aneurysms with 7 T PC-MRI

Antoine Michel Sache, Mohamed Farhat, Philippe Reymond

ObjectiveWall shear stress (WSS) and its derived spatiotemporal parameters have proven to play a major role on intracranial aneurysms (IAs) growth and rupture. This study aims to demonstrate how ultra-high field (UHF) 7 T phase contrast magnetic resonance ...

SPRINGER2023

A 1D model of the arterial circulation in mice

Nikolaos Stergiopoulos, Bram Trachet, Philippe Reymond, Lydia Aslanidou

At a time of growing concern over the ethics of animal experimentation, mouse models are still an indispensable source of insight into the cardiovascular system and its most frequent pathologies. Nevertheless, reference data on the murine cardiovascular an ...

2016

Fluid Structure Interaction Simulations of Physiological Blood Flow in the Aorta

Dimitrios Kontaxakis, Alfio Quarteroni, Nikolaos Stergiopoulos, Simone Deparis, Philippe Reymond, Paolo Crosetto

The numerical tools to simulate blood flow in the cardiovascular system are constantly developing due to the great clinical interest and to scientific advances in mathematical models and computational power. The present work aims to address and validate ne ...

Elsevier2011