Publications by Jean-Vincent Le Bé

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The neocortex is the most computationally advanced portion of the brain. It is currently assumed to be composed of a large number of "cortical columns" – intricate arrangements of cortical neurons approximately 300-500 µm in diameter and 2-5 mm in height i ...

Neocortical pyramidal cells (PCs) project to various cortical and subcortical targets. In layer V, the population of thick tufted PCs (TTCs) projects to subcortical targets such as the tectum, brainstem, and spinal cord. Another population of layer V PCs p ...

The local microcircuitry of the neocortex is structurally a tabula rasa, with the axon of each pyramidal neuron having numerous submicrometer appositions with the dendrites of all neighboring pyramidal neurons, but is functionally highly selective, with sy ...

A single intra-peritoneal injection of valproic acid (VPA) on embryonic day (ED) 11.5 to pregnant rats has been shown to produce severe autistic-like symptoms in the offspring. Previous studies showed that the microcircuitry is hyperreactive due to hyperco ...

Jean-Vincent Le Bé

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Structure and dynamics of the neocortical microcircuit connectivity

Morphological, electrophysiological, and synaptic properties of corticocallosal pyramidal cells in the neonatal rat neocortex

Spontaneous and evoked synaptic rewiring in the neonatal neocortex

Enhanced long-term microcircuit plasticity in the valproic Acid animal model of autism

Un nouveau mécanisme de mémoire : connexions et déconnexions de neurones dans le néocortex de jeunes rats [A new mechanism for memory: neuronal networks rewiring in the young rat neocortex]