Publications by Dominique Pioletti

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Tendon afflictions are very common, and their negative impact is high both at the workplace and in leisure activities. Tendinopathies are increasing in prevalence and can lead to tendon ruptures, where healing is a long process with outcomes that are often ...

Une étude in vivo de stimulation mécanique de tibia de souris est en cours au LBO actuellement. Nous comparons la réponse métabolique des souris C57BL6 wild type ou betaArrestin2 KO. betaArrestin2 est une molécule associée à l'internalisation de la Parathyroid Hormone. Les souris betaArrestin2 KO développent une ossature plus petite que les wild type. C'est pourquoi il est nécessaire de calibrer la force mécanique appliquée sur les tibias en fonction de la souche génétique pour que la contrainte ressentie s

L'os est constamment remodelé et s'adapte en particulier afin d'optimiser sa structure aux sollicitations mécaniques. Il semble de plus en plus évident que les cellules osseuses de type osteocytes sont utilisées par le corps comme capteur du stimulus mécanique qui est ensuite traduit en réponse biologique. Cependant, on connait beaucoup moins bien le processus par lequel les cellules "sentent" le stimulus mécanique pour le traduire en réponse biologique, phénomène appelé "mecanotransduction". Un des projets

Temperature has been extensively explored as a trigger to control the delivery of a payload from environment-sensitive polymers. The need for an external heat source only allows limited spatiotem- poral control over the delivery process. We propose a new a ...

Dominique Pioletti

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Redesigning commercial total hip replacement instruments: an educational project

Stability enhancement using hyaluronic acid gels for delivery of human fetal progenitor tenocytes

Baseplate compression screw force of a reversed shoulder prosthesis

Chondrogenic modulation by thermogenesis

Development of a nano-composite drug eluting bone plug enhancing fixation of screws in low quality bone

Comparaison du stimulus mécanique appliqué in vivo sur un tibia de souris entre une souris C57BL6 wild type et une souris C57BL6 betaArrestin2 KO

Modélisation du stimulus mécanique appliqué in vivo sur un tibia de souris

Total joint replacement and aseptic loosening

Development Of A 3D Piezo-Biomaterial To Study Cartilage Electro-Mechanobiology

Controlled release from a mechanically-stimulated thermosensitive self-heating composite hydrogel

Human fetal bone cells for tissue engineering.

Characterization of human fetal bone cells for bone tissue engineering.

Effect of the scapulo-humeral rhythm on anatomical and reverse shoulder prostheses.

Theoretical framework for the design of orthopedic implants as drug delivery systems

Matrix production by human fetal cartilage and spine cells

A multidisciplinary approach to quantitatively assess cutaneous reconstructions and skin grafts.

Estimation of biomechanical stimulus in bone scaffolds in vivo: multi-scale finite element model.

Calcium phosphate cement augmentation of cancellous bone screws can compensate for the loss of cortical fixation.

Fetal epiphyseal chondrocyte master cell banking for osteochondral repair and regeneration.

Finite element model of the human anterior cruciate ligament