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This lecture covers the principles of electrokinetic devices, focusing on leveraging nanoscale structures to improve device performance. Topics include nanoscale heat transfer, energy conversion, liquids transport properties, and the control of radiative heat transfer. The lecture also explores the benefits of nanostructures in energy conversion devices and the potential of electrokinetic devices. Various concepts such as thermoelectric devices, light-energy conversion devices, and the control of radiative heat transfer are discussed in detail.