Lecture

Biomedical Microrobots: Precision Medicine and Tissue Mechanics

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Description

This lecture explores the development of biomedical microrobots for precision medicine, focusing on accessing tissues with microengineered instruments. It delves into the challenges of navigating inside the human body, particularly in small vessels, and presents innovative solutions like flow-driven navigation and magnetic steering. The talk also covers the application of microrobots in clinical settings, such as retinoblastoma treatment, and discusses the potential of acoustic actuation as an alternative to magnetics. Furthermore, it delves into contractile tissue mechanics, including force fields in living tissues, cell migration, and tissue flow, aiming to understand and control tissue morphogenesis through experimental and theoretical approaches.

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Related concepts (32)

Morphogenesis

Morphogenesis (from the Greek morphê shape and genesis creation, literally "the generation of form") is the biological process that causes a cell, tissue or organism to develop its shape. It is one of three fundamental aspects of developmental biology along with the control of tissue growth and patterning of cellular differentiation. The process controls the organized spatial distribution of cells during the embryonic development of an organism.

Navigation

Navigation is a field of study that focuses on the process of monitoring and controlling the movement of a craft or vehicle from one place to another. The field of navigation includes four general categories: land navigation, marine navigation, aeronautic navigation, and space navigation. It is also the term of art used for the specialized knowledge used by navigators to perform navigation tasks. All navigational techniques involve locating the navigator's position compared to known locations or patterns.

Morphogen

A morphogen is a substance whose non-uniform distribution governs the pattern of tissue development in the process of morphogenesis or pattern formation, one of the core processes of developmental biology, establishing positions of the various specialized cell types within a tissue. More specifically, a morphogen is a signaling molecule that acts directly on cells to produce specific cellular responses depending on its local concentration.

Radio navigation

Radio navigation or radionavigation is the application of radio frequencies to determine a position of an object on the Earth, either the vessel or an obstruction. Like radiolocation, it is a type of radiodetermination. The basic principles are measurements from/to electric beacons, especially Angular directions, e.g. by bearing, radio phases or interferometry, Distances, e.g. ranging by measurement of time of flight between one transmitter and multiple receivers or vice versa, Distance differences by measurement of times of arrival of signals from one transmitter to multiple receivers or vice versa Partly also velocity, e.

Developmental biology

Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. The main processes involved in the embryonic development of animals are: tissue patterning (via regional specification and patterned cell differentiation); tissue growth; and tissue morphogenesis.

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