Fixed point (mathematics)hatnote|1=Fixed points in mathematics are not to be confused with other uses of "fixed point", or stationary points where math|1=f(x) = 0. In mathematics, a fixed point (sometimes shortened to fixpoint), also known as an invariant point, is a value that does not change under a given transformation. Specifically for functions, a fixed point is an element that is mapped to itself by the function. Formally, c is a fixed point of a function f if c belongs to both the domain and the codomain of f, and f(c) = c.
Fixed-point iterationIn numerical analysis, fixed-point iteration is a method of computing fixed points of a function. More specifically, given a function defined on the real numbers with real values and given a point in the domain of , the fixed-point iteration is which gives rise to the sequence of iterated function applications which is hoped to converge to a point . If is continuous, then one can prove that the obtained is a fixed point of , i.e., More generally, the function can be defined on any metric space with values in that same space.
Fixed-point theoremIn mathematics, a fixed-point theorem is a result saying that a function F will have at least one fixed point (a point x for which F(x) = x), under some conditions on F that can be stated in general terms. The Banach fixed-point theorem (1922) gives a general criterion guaranteeing that, if it is satisfied, the procedure of iterating a function yields a fixed point.
Kakutani fixed-point theoremIn mathematical analysis, the Kakutani fixed-point theorem is a fixed-point theorem for set-valued functions. It provides sufficient conditions for a set-valued function defined on a convex, compact subset of a Euclidean space to have a fixed point, i.e. a point which is mapped to a set containing it. The Kakutani fixed point theorem is a generalization of the Brouwer fixed point theorem. The Brouwer fixed point theorem is a fundamental result in topology which proves the existence of fixed points for continuous functions defined on compact, convex subsets of Euclidean spaces.
Brouwer fixed-point theoremBrouwer's fixed-point theorem is a fixed-point theorem in topology, named after L. E. J. (Bertus) Brouwer. It states that for any continuous function mapping a nonempty compact convex set to itself there is a point such that . The simplest forms of Brouwer's theorem are for continuous functions from a closed interval in the real numbers to itself or from a closed disk to itself. A more general form than the latter is for continuous functions from a nonempty convex compact subset of Euclidean space to itself.
Gene expression profilingIn the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell. Several transcriptomics technologies can be used to generate the necessary data to analyse.
Gene expressionGene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, and ultimately affect a phenotype. These products are often proteins, but in non-protein-coding genes such as transfer RNA (tRNA) and small nuclear RNA (snRNA), the product is a functional non-coding RNA.
Regulation of gene expressionRegulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA). Sophisticated programs of gene expression are widely observed in biology, for example to trigger developmental pathways, respond to environmental stimuli, or adapt to new food sources. Virtually any step of gene expression can be modulated, from transcriptional initiation, to RNA processing, and to the post-translational modification of a protein.
Serial analysis of gene expressionSerial Analysis of Gene Expression (SAGE) is a transcriptomic technique used by molecular biologists to produce a snapshot of the messenger RNA population in a sample of interest in the form of small tags that correspond to fragments of those transcripts. Several variants have been developed since, most notably a more robust version, LongSAGE, RL-SAGE and the most recent SuperSAGE. Many of these have improved the technique with the capture of longer tags, enabling more confident identification of a source gene.
Spatiotemporal gene expressionSpatiotemporal gene expression is the activation of genes within specific tissues of an organism at specific times during development. Gene activation patterns vary widely in complexity. Some are straightforward and static, such as the pattern of tubulin, which is expressed in all cells at all times in life. Some, on the other hand, are extraordinarily intricate and difficult to predict and model, with expression fluctuating wildly from minute to minute or from cell to cell.
Hilbert curveThe Hilbert curve (also known as the Hilbert space-filling curve) is a continuous fractal space-filling curve first described by the German mathematician David Hilbert in 1891, as a variant of the space-filling Peano curves discovered by Giuseppe Peano in 1890. Because it is space-filling, its Hausdorff dimension is 2 (precisely, its image is the unit square, whose dimension is 2 in any definition of dimension; its graph is a compact set homeomorphic to the closed unit interval, with Hausdorff dimension 2).
TI-BASICTI-BASIC is the official name of a BASIC-like language built into Texas Instruments (TI)'s graphing calculators. TI-BASIC is a language family of three different and incompatible versions, released on different products: TI-BASIC 83 (on Z80 processor) for TI-83 series, TI-84 Plus series TI-BASIC 89 (on 68k processor) for TI-89 series, TI-92 series, Voyage 200 TI-BASIC Nspire (on ARM processor) for TI-Nspire and TI-Nspire CAS TI rarely refers to the language by name, but the name TI-BASIC has been used in some developer documentation.
TI-83 seriesThe TI-83 series is a series of graphing calculators manufactured by Texas Instruments. The original TI-83 is itself an upgraded version of the TI-82. Released in 1996, it was one of the most popular graphing calculators for students. In addition to the functions present on normal scientific calculators, the TI-83 includes many features, including function graphing, polar/parametric/sequence graphing modes, statistics, trigonometric, and algebraic functions, along with many useful applications.
TI-Nspire seriesThe TI-Nspire is a graphing calculator line made by Texas Instruments, with the first version released in July 2007. The calculators feature a non-QWERTY keyboard and a different key-by-key layout than Texas Instruments's previous flagship calculators such as the TI-89 series. The original TI-Nspire was developed out of the TI PLT SHH1 prototype calculator (which itself was derived from the Casio ClassPad 300), the TI-92 series of calculators released in 1995, and the TI-89 series of calculators released in 1998.
TI-92 seriesThe TI-92 series of graphing calculators are a line of calculators produced by Texas Instruments. They include: the TI-92 (1995), the TI-92 II (1996), the TI-92 Plus (1998, 1999) and the Voyage 200 (2002). The design of these relatively large calculators includes a QWERTY keyboard. Because of this keyboard, it was given the status of a "computer" rather than "calculator" by American testing facilities and cannot be used on tests such as the SAT or AP Exams while the similar TI-89 can be.
Cas9Cas9 (CRISPR associated protein 9, formerly called Cas5, Csn1, or Csx12) is a 160 kilodalton protein which plays a vital role in the immunological defense of certain bacteria against DNA viruses and plasmids, and is heavily utilized in genetic engineering applications. Its main function is to cut DNA and thereby alter a cell's genome. The CRISPR-Cas9 genome editing technique was a significant contributor to the Nobel Prize in Chemistry in 2020 being awarded to Emmanuelle Charpentier and Jennifer Doudna.
Lefschetz fixed-point theoremIn mathematics, the Lefschetz fixed-point theorem is a formula that counts the fixed points of a continuous mapping from a compact topological space to itself by means of traces of the induced mappings on the homology groups of . It is named after Solomon Lefschetz, who first stated it in 1926. The counting is subject to an imputed multiplicity at a fixed point called the fixed-point index. A weak version of the theorem is enough to show that a mapping without any fixed point must have rather special topological properties (like a rotation of a circle).
GeneIn biology, the word gene (from γένος, génos; meaning generation or birth or gender) can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function.
CRISPRCRISPR (ˈkrɪspər) (an acronym for clustered regularly interspaced short palindromic repeats) is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. These sequences are derived from DNA fragments of bacteriophages that had previously infected the prokaryote. They are used to detect and destroy DNA from similar bacteriophages during subsequent infections. Hence these sequences play a key role in the antiviral (i.e. anti-phage) defense system of prokaryotes and provide a form of acquired immunity.
MKS system of unitsThe MKS system of units is a physical system of measurement that uses the metre, kilogram, and second (MKS) as base units. The modern International System of Units (SI) was originally created as a formalization of the MKS system, and although the SI has been redefined several times since then and is now based entirely on fundamental physical constants, it still closely approximates the original MKS system for most practical purposes. By the mid-19th century, there was a demand by scientists to define a coherent system of units.
