Lecture

Microbial Growth and Limiting Factors

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Description

This lecture covers the exponential growth of bacterial cells, biomass production, and the limitations imposed by substrate availability. It also discusses the relationship between glucose concentration and growth rate, as well as the concept of chemostats in continuous culture. The Law of the Minimum is explained through examples, illustrating how nutrient limitations affect biomass production. The lecture delves into the production of Polyhydroxyalkanoates (PHAs) by bacteria under nutrient-limiting conditions, and the applications of tailored PHA production. Various factors influencing microbial growth, such as carbon and nitrogen sources, are explored, along with the prediction of growth limitations in dual-limiting conditions.

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Official source

Ontological neighbourhood

Biology

Ecology: Ecosystems

Related concepts (29)

Liebig's law of the minimum

Liebig's law of the minimum, often simply called Liebig's law or the law of the minimum, is a principle developed in agricultural science by Carl Sprengel (1840) and later popularized by Justus von Liebig. It states that growth is dictated not by total resources available, but by the scarcest resource (limiting factor). The law has also been applied to biological populations and ecosystem models for factors such as sunlight or mineral nutrients.

Polyhydroxyalkanoates

Polyhydroxyalkanoates or PHAs are polyesters produced in nature by numerous microorganisms, including through bacterial fermentation of sugars or lipids. When produced by bacteria they serve as both a source of energy and as a carbon store. More than 150 different monomers can be combined within this family to give materials with extremely different properties. These plastics are biodegradable and are used in the production of bioplastics. They can be either thermoplastic or elastomeric materials, with melting points ranging from 40 to 180 °C.

Nitrogen cycle

The nitrogen cycle is the biogeochemical cycle by which nitrogen is converted into multiple chemical forms as it circulates among atmospheric, terrestrial, and marine ecosystems. The conversion of nitrogen can be carried out through both biological and physical processes. Important processes in the nitrogen cycle include fixation, ammonification, nitrification, and denitrification. The majority of Earth's atmosphere (78%) is atmospheric nitrogen, making it the largest source of nitrogen.

Biodegradable plastic

Biodegradable plastics are plastics that can be decomposed by the action of living organisms, usually microbes, into water, carbon dioxide, and biomass. Biodegradable plastics are commonly produced with renewable raw materials, micro-organisms, petrochemicals, or combinations of all three. While the words "bioplastic" and "biodegradable plastic" are similar, they are not synonymous. Not all bioplastics (plastics derived partly or entirely from biomass) are biodegradable, and some biodegradable plastics are fully petroleum based.

Nitrogen fixation

Nitrogen fixation is a chemical process by which molecular nitrogen (N2), which has a strong triple covalent bond, is converted into ammonia (NH3) or related nitrogenous compounds, typically in soil or aquatic systems but also in industry. The nitrogen in air is molecular dinitrogen, a relatively nonreactive molecule that is metabolically useless to all but a few microorganisms. Biological nitrogen fixation or diazotrophy is an important microbe-mediated process that converts dinitrogen (N2) gas to ammonia (NH3) using the nitrogenase protein complex (Nif).

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