Mediaspace scheduled maintenance: Aug 25, 2026 07:00 - 12:00 AM. During this time, videos will be temporarily unavailable. Check status updates.

Lecture

Low-dose STEM Imaging of Beam-Sensitive Materials

Description

This lecture covers the challenges of imaging beam-sensitive materials using low-dose 2D and 4D STEM techniques, focusing on hybrid perovskites. It discusses the principles of 4D STEM, dose control, and intelligent data processing for signal extraction. The presentation explores the effects of beam damage on materials, growth processes, and the use of pixelated detectors for efficient detection. Additionally, it delves into the application of ptychography for achieving atom resolution imaging and the reconstruction methods for complex nanostructures. The lecture concludes with a discussion on the optimal transfer functions, signal-to-noise spectrum, and the benefits of noise-normalized transfer functions in ptychography.

This video is available exclusively on Mediaspace for a restricted audience. Please log in to MediaSpace to access it if you have the necessary permissions.

Watch on Mediaspace

Official source

Ontological neighbourhood

Biological engineering

Biomedical engineering: Tissue engineering

Related concepts (31)

Stem cell

In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type.

Adult stem cell

Adult stem cells are undifferentiated cells, found throughout the body after development, that multiply by cell division to replenish dying cells and regenerate damaged tissues. Also known as somatic stem cells (from Greek σωματικóς, meaning of the body), they can be found in juvenile, adult animals, and humans, unlike embryonic stem cells. Scientific interest in adult stem cells is centered around two main characteristics.

Embryonic stem cell

Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre-implantation embryo. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells. Isolating the inner cell mass (embryoblast) using immunosurgery results in destruction of the blastocyst, a process which raises ethical issues, including whether or not embryos at the pre-implantation stage have the same moral considerations as embryos in the post-implantation stage of development.

Induced pluripotent stem cell

Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell. The iPSC technology was pioneered by Shinya Yamanaka and Kazutoshi Takahashi in Kyoto, Japan, who together showed in 2006 that the introduction of four specific genes (named Myc, Oct3/4, Sox2 and Klf4), collectively known as Yamanaka factors, encoding transcription factors could convert somatic cells into pluripotent stem cells.

Stem-cell therapy

Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition. , the only established therapy using stem cells is hematopoietic stem cell transplantation. This usually takes the form of a bone-marrow transplantation, but the cells can also be derived from umbilical cord blood. Research is underway to develop various sources for stem cells as well as to apply stem-cell treatments for neurodegenerative diseases and conditions such as diabetes and heart disease.

Related lectures (32)

Stem Cell Biology: Essentials and Applications

Covers the essentials of stem cell biology, including major types, properties, and applications, as well as challenges in research.

Stem Cell Applications: Models, Therapy, and Cloning

Explores the applications of embryonic stem cells in biomedical research, disease modeling, and potential therapeutic interventions, including the types of stem cells and the challenges they face.

Stem Cells: Types, Regulation, and Applications

Covers the basic notions about stem cells, their types, regulation, and potential applications in regenerative medicine.

Stem Cells: Basics and Applications

Explores the basics of stem cells, their types, applications, and challenges in research.

Stem Cells and Organoid Engineering