Connective tissueConnective tissue is one of the four primary types of animal tissue, along with epithelial tissue, muscle tissue, and nervous tissue. It develops from the mesenchyme, derived from the mesoderm, the middle embryonic germ layer. Connective tissue is found in between other tissues everywhere in the body, including the nervous system. The three meninges, membranes that envelop the brain and spinal cord, are composed of connective tissue. Most types of connective tissue consists of three main components: elastic and collagen fibers, ground substance, and cells.
SystoleSystole (ˈsɪstəli ) is the part of the cardiac cycle during which some chambers of the heart contract after refilling with blood. The term originates, via Neo-Latin, from Ancient Greek συστολή (sustolē), from συστέλλειν (sustéllein 'to contract'; from σύν sun 'together' + στέλλειν stéllein 'to send'), and is similar to the use of the English term to squeeze. The mammalian heart has four chambers: the left atrium above the left ventricle (lighter pink, see graphic), which two are connected through the mitral (or bicuspid) valve; and the right atrium above the right ventricle (lighter blue), connected through the tricuspid valve.
Smooth muscleSmooth muscle is an involuntary non-striated muscle, so-called because it has no sarcomeres and therefore no striations (bands or stripes). It is divided into two subgroups, single-unit and multiunit smooth muscle. Within single-unit muscle, the whole bundle or sheet of smooth muscle cells contracts as a syncytium. Smooth muscle is found in the walls of hollow organs, including the stomach, intestines, bladder and uterus. In the walls of blood vessels, and lymph vessels, (excluding blood and lymph capillaries) it is known as vascular smooth muscle.
EndotheliumThe endothelium (: endothelia) is a single layer of squamous endothelial cells that line the interior surface of blood vessels and lymphatic vessels. The endothelium forms an interface between circulating blood or lymph in the lumen and the rest of the vessel wall. Endothelial cells form the barrier between vessels and tissue and control the flow of substances and fluid into and out of a tissue. Endothelial cells in direct contact with blood are called vascular endothelial cells whereas those in direct contact with lymph are known as lymphatic endothelial cells.
Blood pressureBlood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure" refers to the pressure in a brachial artery, where it is most commonly measured. Blood pressure is usually expressed in terms of the systolic pressure (maximum pressure during one heartbeat) over diastolic pressure (minimum pressure between two heartbeats) in the cardiac cycle.
CollagenCollagen (ˈkɒlədʒən) is the main structural protein in the extracellular matrix found in the body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole-body protein content. Collagen consists of amino acids bound together to form a triple helix of elongated fibril known as a collagen helix. It is mostly found in connective tissue such as cartilage, bones, tendons, ligaments, and skin.
DiastoleDiastole (daɪˈæstəli ) is the relaxed phase of the cardiac cycle when the chambers of the heart are re-filling with blood. The contrasting phase is systole when the heart chambers are contracting. Atrial diastole is the relaxing of the atria, and ventricular diastole the relaxing of the ventricles. The term originates from the Greek word διαστολή (diastolē), meaning "dilation", from διά (diá, "apart") + στέλλειν (stéllein, "to send"). A typical heart rate is 75 beats per minute (bpm), which means that the cardiac cycle that produces one heartbeat, lasts for less than one second.
Indiana University BloomingtonIndiana University Bloomington (IU Bloomington, Indiana University, IU, or simply Indiana) is a public research university in Bloomington, Indiana. It is the flagship campus of Indiana University and its largest campus with over 40,000 students. Indiana University is a member of the Association of American Universities and is classified among "R1: Doctoral Universities – Very high research activity".
Indiana UniversityIndiana University (IU) is a system of public universities in the U.S. state of Indiana. Indiana University has two core campuses, five regional campuses, and two regional centers under the administration of IUPUI. Indiana University Bloomington (IU Bloomington) is the flagship campus of Indiana University.
Indiana University School of MedicineThe Indiana University School of Medicine (IUSM) is a major, multi-campus medical school located throughout the U.S. state of Indiana and is the graduate medical school of Indiana University. There are nine campuses throughout the state; the principal research, educational, and medical center is located on the Indiana University–Purdue University Indianapolis (IUPUI) campus in Indianapolis. With 1,452 MD students, 203 PhD students, and 1,356 residents and fellows in the 2022–23 academic year, IUSM is the largest medical school in the United States.
Indiana University–Purdue University Fort WayneIndiana University–Purdue University Fort Wayne (IPFW) was a public university in Fort Wayne, Indiana. Founded in 1964, IPFW was a cooperatively-managed regional campus of two state university systems: Indiana University and Purdue University. IPFW hit its highest enrollment in 2014, with 13,459 undergraduate and postgraduate students in nine colleges and schools, including a branch of the Indiana University School of Medicine. During its last academic year (2017–2018), IPFW had a total enrollment of 10,414 students.
Indiana University Robert H. McKinney School of LawThe Indiana University Robert H. McKinney School of Law (IU McKinney) is located on the campus of Indiana University – Purdue University Indianapolis (IUPUI) in Indianapolis, Indiana, the urban campus of Indiana University. In the summer of 2001, the school moved to its new building, Lawrence W. Inlow Hall. IU McKinney is one of two law schools operated by Indiana University, the other being the Indiana University Maurer School of Law (IU Maurer) in Bloomington.
