Lectures related to Drug Targets: Nuclear Receptors

Nuclear Receptors: Drug Targets

Explores nuclear receptors, their role in drug pharmacology, and physiological functions in adipose tissue and glucose homeostasis.

Regulation Mechanisms Overview

Covers phosphorylation, ubiquitinylation, methylation, and more in biological regulation.

Pharmacodynamics: Acid-sensing ion channels and Drug Targets

Explores acid-sensing ion channels, drug targets, and ligand-receptor binding.

Eukaryotic Transcription: Initiation and Elongation

Explores eukaryotic transcription initiation, elongation, and gene regulation complexity.

Prokaryotic Transcription: Operons and Sigma Factors

Explores prokaryotic transcription, operons, sigma factors, gene regulation, and DNA loops in bacteria.

Heat Shock Transcription Factors: Regulation and Targets

Explores Heat Shock Transcription Factors' regulation and targets in response to stress, including HSF2's dynamic expression and impact on cell adhesion.

Cellular Communication and Metabolism: Energy Transformation Principles

Discusses cellular communication, metabolism, energy transformation, and the role of enzymes in biochemical reactions.

Altered Metabolism in Cancer: Warburg Effect and MYC Regulation

Explores altered cancer metabolism, MYC regulation, Rb and p53 pathways, AKT re-activation, and protein-protein interactions.

Myc-Max: Protein Interactions and Cell Proliferation

Explores the interactions between Myc, Max, and Miz proteins in cell proliferation.

Gene Regulation: Transcription Mechanisms and Chromatin Accessibility MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores gene regulation through transcription mechanisms and chromatin accessibility, emphasizing the importance of transcription factors and gene regulatory networks.

Drug Targets: Adrenergic Signaling

Explores drug targets and adrenergic signaling, covering receptors, enzymes, and transporter proteins.

Pharmacodynamics: Ligand-Receptor Interactions and Drug Effects

Explores ligand-receptor interactions, drug effects, modulation mechanisms, and factors influencing drug responses.

RNA Functions: Transcription and Translation

Explores RNA functions in transcription, translation, and gene regulation, including defense mechanisms and viral infections.

Gene Regulatory Networks MOOC: Neuroscience Reconstructed: Genetics and Brain Development

Explores how gene regulatory networks encode changes in cell development and the importance of interactions between different regulatory networks.

Neuroepigenetics: Chromatin Structure & Inheritance

Delves into neuroepigenetics, covering chromatin structure, histone modifications, DNA methylation, and their impact on gene transcription and inheritance.

Ubiquitination: Protein Degradation

Explores ubiquitination, protein degradation, and cellular regulation through ubiquitin tagging, covering various cellular processes and pathways.

DNA Structure and Gene Expression

Explores DNA structure, gene expression, RNA transcription, and protein manufacturing in cells, including the crucial role of RNA polymerase.

Nuclear Receptors: Signalling and Health Implications Log in to Mediaspace to watch this video

Explores nuclear receptors, JAK-STAT pathway, growth factors, endocrine disruptors, and estrogen receptors.

Nuclear Receptors: Core Signaling Log in to Mediaspace to watch this video

Explores nuclear receptors' core signaling and the impact of endocrine disruptors on the endocrine system, including the inhibitory effects of compounds like eugenol on the estrogen receptor.

Genetic Circuits: Synthetic Biology Log in to Mediaspace to watch this video

Explores genetic circuits design in synthetic biology, from regulatory mechanisms to plasmid construction.