Lecture

Supramolecular Chemistry: Coordination and Topology

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In course

CH-424: Supramolecular chemistry

The course provides an introduction to supramolecular chemistry. In addition, current trends are discussed using recent publications in this area. ...

Description

This lecture covers the principles of supramolecular chemistry, focusing on coordination complexes and molecular topology. Topics include the formation of metal ion arrays, helicates, molecular grids, rotaxanes, catenanes, and knots. The instructor emphasizes the self-assembly processes and the unique properties of mechanically interlocked molecules found in nature.

Instructor

Kay Severin

Kay Severin was born in Germany in 1967. He obtained his Ph.D. in 1995 with a thesis in the group of Prof. W. Beck, University of Munich. Subsequently, he joined the group of Prof. M. R. Ghadiri as a postdoctoral fellow. In 1997, he started independent research projects ("Habilitation") at the Department of Chemistry, University of Munich. In 2001, he became assistant professor at the Institute of Chemical Sciences and Engineering at the Swiss Federal Institute of Technology, Lausanne (EPFL). Since 2009, he is full professor at the same institute. Awards: Bayerischer Habilitations Förderpreis (1997), ADUC award of the year (2001), Heinz Maier-Leibnitz award of the DFG (2001), award of the Karl-Ziegler foundation (2001), Arnold Sommerfeld award of the Bavarian Academy of Science (2001), Werner Prize of The Swiss Chemical Society (2003), Otto Roelen Medal of the DECHEMA (2005), award for chemistry of the Academy of Sciences, Göttingen (2007), Dalton Transactions European Lectureship (2008).

Official source

Ontological neighbourhood

Chemical engineering

Nanotechnology: Topics in nanotechnology

Related concepts (31)

Mechanically interlocked molecular architectures

In chemistry, mechanically interlocked molecular architectures (MIMAs) are molecules that are connected as a consequence of their topology. This connection of molecules is analogous to keys on a keychain loop. The keys are not directly connected to the keychain loop but they cannot be separated without breaking the loop. On the molecular level, the interlocked molecules cannot be separated without the breaking of the covalent bonds that comprise the conjoined molecules; this is referred to as a mechanical bond.

Supramolecular assembly

In chemistry, a supramolecular assembly is a complex of molecules held together by noncovalent bonds. While a supramolecular assembly can be simply composed of two molecules (e.g., a DNA double helix or an inclusion compound), or a defined number of stoichiometrically interacting molecules within a quaternary complex, it is more often used to denote larger complexes composed of indefinite numbers of molecules that form sphere-, rod-, or sheet-like species.

Molecular self-assembly

In chemistry and materials science, molecular self-assembly is the process by which molecules adopt a defined arrangement without guidance or management from an outside source. There are two types of self-assembly: intermolecular and intramolecular. Commonly, the term molecular self-assembly refers to the former, while the latter is more commonly called folding. Molecular self-assembly is a key concept in supramolecular chemistry. This is because assembly of molecules in such systems is directed through non-covalent interactions (e.

Self-assembly of nanoparticles

Nanoparticles are classified as having at least one of three dimensions be in the range of 1-100 nm. The small size of nanoparticles allows them to have unique characteristics which may not be possible on the macro-scale. Self-assembly is the spontaneous organization of smaller subunits to form larger, well-organized patterns. For nanoparticles, this spontaneous assembly is a consequence of interactions between the particles aimed at achieving a thermodynamic equilibrium and reducing the system’s free energy.

Molecular machine

Molecular machines are a class of molecules typically described as an assembly of a discrete number of molecular components intended to produce mechanical movements in response to specific stimuli, mimicking macromolecular devices such as switches and motors. Naturally occurring or biological molecular machines are responsible for vital living processes such as DNA replication and ATP synthesis. Kinesins and ribosomes are examples of molecular machines, and they often take the form of multi-protein complexes.

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