Lecture

Single Molecule Mass Spectrometry: Electrostatic Actuation and Detection

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Description

This lecture discusses the principles of single molecule mass spectrometry, focusing on electrostatic actuation and detection methods. Topics include function value analysis, frequency shifts, oxidation, and reduction processes in mass spectrometry.

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Related concepts (19)

Complex analysis

Complex analysis, traditionally known as the theory of functions of a complex variable, is the branch of mathematical analysis that investigates functions of complex numbers. It is helpful in many branches of mathematics, including algebraic geometry, number theory, analytic combinatorics, applied mathematics; as well as in physics, including the branches of hydrodynamics, thermodynamics, quantum mechanics, and twistor theory. By extension, use of complex analysis also has applications in engineering fields such as nuclear, aerospace, mechanical and electrical engineering.

Mass spectrometry

Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a mass spectrum, a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is used in many different fields and is applied to pure samples as well as complex mixtures. A mass spectrum is a type of plot of the ion signal as a function of the mass-to-charge ratio.

Real-valued function

In mathematics, a real-valued function is a function whose values are real numbers. In other words, it is a function that assigns a real number to each member of its domain. Real-valued functions of a real variable (commonly called real functions) and real-valued functions of several real variables are the main object of study of calculus and, more generally, real analysis. In particular, many function spaces consist of real-valued functions. Let be the set of all functions from a set X to real numbers .

Real analysis

In mathematics, the branch of real analysis studies the behavior of real numbers, sequences and series of real numbers, and real functions. Some particular properties of real-valued sequences and functions that real analysis studies include convergence, limits, continuity, smoothness, differentiability and integrability. Real analysis is distinguished from complex analysis, which deals with the study of complex numbers and their functions.

Ion-mobility spectrometry–mass spectrometry

Ion mobility spectrometry–mass spectrometry (IMS-MS) is an analytical chemistry method that separates gas phase ions based on their interaction with a collision gas and their masses. In the first step, the ions are separated according to their mobility through a buffer gas on a millisecond timescale using an ion mobility spectrometer. The separated ions are then introduced into a mass analyzer in a second step where their mass-to-charge ratios can be determined on a microsecond timescale.

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