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Lecture

Untitled

In course

NX-436: Advanced methods for human neuromodulation

Neuromodulation is an expending field especially in human translational neuroscience and neurotechnology. This course will introduce to different approaches / technologies for neuromodulation, their underlying mechanisms of action and application in humans ...

Instructor

Friedhelm Christoph Hummel

Official source

https://mediaspace.epfl.ch/media/0_3bj6qnoc

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Related concepts (18)

Neurostimulation

Neurostimulation is the purposeful modulation of the nervous system's activity using invasive (e.g. microelectrodes) or non-invasive means (e.g. transcranial magnetic stimulation or transcranial electric stimulation, tES, such as tDCS or transcranial alternating current stimulation, tACS). Neurostimulation usually refers to the electromagnetic approaches to neuromodulation.

Deep brain stimulation

Deep brain stimulation (DBS) is a neurosurgical procedure involving the placement of a medical device called a neurostimulator, which sends electrical impulses, through implanted electrodes, to specific targets in the brain (the brain nucleus) for the treatment of movement disorders, including Parkinson's disease, essential tremor, dystonia, and other conditions such as obsessive-compulsive disorder (OCD) and epilepsy. While its underlying principles and mechanisms are not fully understood, DBS directly changes brain activity in a controlled manner.

Transcranial direct-current stimulation

Transcranial direct current stimulation (tDCS) is a form of neuromodulation that uses constant, low direct current delivered via electrodes on the head. It was originally developed to help patients with brain injuries or neuropsychiatric conditions such as major depressive disorder. It can be contrasted with cranial electrotherapy stimulation, which generally uses alternating current the same way, as well as transcranial magnetic stimulation. Research shows increasing evidence for tDCS as a treatment for depression.

Transcranial magnetic stimulation

Transcranial magnetic stimulation (TMS) is a noninvasive form of brain stimulation in which a changing magnetic field is used to induce an electric current at a specific area of the brain through electromagnetic induction. An electric pulse generator, or stimulator, is connected to a magnetic coil connected to the scalp. The stimulator generates a changing electric current within the coil which creates a varying magnetic field, inducing a current within a region in the brain itself.

Neuromodulation (medicine)

Neuromodulation is "the alteration of nerve activity through targeted delivery of a stimulus, such as electrical stimulation or chemical agents, to specific neurological sites in the body". It is carried out to normalize – or modulate – nervous tissue function. Neuromodulation is an evolving therapy that can involve a range of electromagnetic stimuli such as a magnetic field (rTMS), an electric current, or a drug instilled directly in the subdural space (intrathecal drug delivery).

Related lectures (33)

Electrical Stimulation Circuit

Covers neurostimulation techniques and electrical stimulation circuits for neural stimulator chips.

Neuroplasticity and Brain Stimulation

Explores neuroplasticity, brain stimulation techniques, and their applications in various neuro-psychiatric disorders and motor learning.

Non-invasive Neuromodulation: Transcranial Stimulation

Explores the history, methods, and applications of non-invasive neuromodulation techniques.

Deep Brain Stimulation

Explores the evolution, principles, and applications of Deep Brain Stimulation, focusing on its history, mechanisms, electrode configurations, and future prospects.

History of Neuromodulation