Non-Invasive Brain Stimulation: Historical Overview and Applications

In course

This course integrates knowledge in basic, systems, clinical and computational neuroscience, and engineering with the goal of translating this integrated knowledge into the development of novel methods, technology for the clinical application for patients ...

Description

This lecture provides a comprehensive overview of non-invasive brain stimulation (NIBS) techniques, focusing on their historical development and clinical applications. It begins with a historical perspective, tracing the origins of brain stimulation methods back to ancient practices, including early electrical treatments for headaches. The instructor discusses significant advancements in the field, particularly the introduction of transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), highlighting their mechanisms and effects on cortical excitability and neuroplasticity. The lecture emphasizes the importance of NIBS in neurorehabilitation, particularly for stroke recovery, and presents evidence from studies demonstrating its efficacy in enhancing motor function and cognitive abilities. The instructor also addresses the challenges of personalization in treatment protocols, advocating for tailored approaches based on individual patient profiles. Finally, the lecture explores future directions for NIBS, including the potential for home-based applications and the integration of advanced technologies to improve treatment outcomes.

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Instructors (4)

Grégoire Courtine

Grégoire Courtine was originally trained in Mathematics and Physics, but received his PhD degree in Experimental Medicine from the University of Pavia, Italy, and the INSERM Plasticity and Motricity, in France, in 2003. From 2004-2007, he held a Post-doctoral Fellow position at the Brain Research Institute, University of California at Los Angeles (UCLA) under the supervision of Dr. Reggie Edgerton, and was a research associate for the Christopher and Dana Reeve Foundation (CDRF). In 2008, he became Assistant Professor at the faculty of Medicine of the University of Zurich where he established his own research laboratory. In 2012, he was nominated Associate Professor at the Swiss Federal Institute of Technology Lausanne (EPFL) where he holds the International paraplegic foundation (IRP) chair in spinal cord repair at the Center for Neuroprosthetics and the Brain Mind Institute. He published several articles proposing radically new approaches for restoring function after spinal cord injury, which were discussed in national and international press extensively. He received numerous honors and awards such as the 2007 UCLA Chancellors award for excellence in post-doctoral research and the 2009 Schellenberg Prize for his innovative research in spinal cord injury awarded by the International Foundation of Research in Paraplegia.

Olaf Blanke

Friedhelm Christoph Hummel

Silvestro Micera

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