Lecture

Post-Genomics and Health Challenges

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In course

HUM-125(b): Health B: Innovation, Equity, Sustainability

Le cours propose une approche interdisciplinaire des grands enjeux de santé mondiale, axée sur les innovations biomédicales, la durabilité, les médicaments, la santé mentale et les politiques de santé. Il développe des compétences de recherche critiques es ...

Description

This lecture by Dr. Luca Chiapperino explores the implications of post-genomics on health and society, focusing on the first 20 years of sequencing the human genome, the paradigm shift in post-genomics, and the molecularization of our biography, experiences, and living environment through epigenetics. The lecture delves into the impact of genomics on medicine, the ethical and societal dimensions of genomic research, and the challenges of personalized medicine. It also discusses the global stakes in health, the role of science and technology studies in defining analytical approaches, and the complexities of genetic testing and gene patenting.

Instructors (4)

Neeraj Dhar

Delphine Preissmann

Teaching & PhD Courses Brain, mind and society HUM-256 This course aims to address topics related to research on brain causes of human actions. The course will introduce to fundamental concepts in psychology, cognitive and social neurosciences and the links between brain and mental illness. Health A: Innovation, Equity, Sustainability HUM-125(a) The course provides an interdisciplinary examination of key global health challenges, focusing on biomedical innovations, pharmaceut

Luca Chiapperino

Expertise Social Studies of Science; Science and Technology Studies; Public Health Ethics; Applied Philosophy; Sustainability Transitions Teaching & PhD Courses Health A: Innovation, Equity, Sustainability HUM-125(a) The course provides an interdisciplinary examination of key global health challenges, focusing on biomedical innovations, pharmaceuticals, sustainability, mental health, and health policies. It offer a critical skillset to engineering students approaching these complex health ch

Thomas David

Teaching & PhD PhD Students Joel Swai Praz Courses Health B: Innovation, Equity, Sustainability HUM-125(b) The course provides an interdisciplinary examination of key global health challenges, focusing on biomedical innovations, pharmaceuticals, sustainability, mental health, and health policies. It offer a critical skillset to engineering students approaching these complex health challenges.

Official source

Ontological neighbourhood

Biology

Genetics: Genomics, Human genetics

Related concepts (32)

Genetic testing

Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, or through biochemical analysis to measure specific protein output. In a medical setting, genetic testing can be used to diagnose or rule out suspected genetic disorders, predict risks for specific conditions, or gain information that can be used to customize medical treatments based on an individual's genetic makeup.

DNA sequencing

DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has become indispensable for basic biological research, DNA Genographic Projects and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics.

Genetic genealogy

Genetic genealogy is the use of genealogical DNA tests, i.e., DNA profiling and DNA testing, in combination with traditional genealogical methods, to infer genetic relationships between individuals. This application of genetics came to be used by family historians in the 21st century, as DNA tests became affordable. The tests have been promoted by amateur groups, such as surname study groups or regional genealogical groups, as well as research projects such as the Genographic Project. about 30 million people had been tested.

Exome sequencing

Exome sequencing, also known as whole exome sequencing (WES), is a genomic technique for sequencing all of the protein-coding regions of genes in a genome (known as the exome). It consists of two steps: the first step is to select only the subset of DNA that encodes proteins. These regions are known as exons—humans have about 180,000 exons, constituting about 1% of the human genome, or approximately 30 million base pairs. The second step is to sequence the exonic DNA using any high-throughput DNA sequencing technology.

Genetic counseling

Genetic counseling is the process of investigating individuals and families affected by or at risk of genetic disorders to help them understand and adapt to the medical, psychological and familial implications of genetic contributions to disease. This field is considered necessary for the implementation of genomic medicine.

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