Course

BIO-480: Neuroscience: from molecular mechanisms to disease

Summary

The goal of the course is to guide students through the essential aspects of molecular neuroscience and neurodegenerative diseases. The student will gain the ability to dissect the molecular basis of disease in the nervous system in order to begin to understand and identify therapeutic strategies.

Lectures

Instructors (2)

Bernard Schneider

Teaching & PhD PhD Students Yesica Gloria, Christian Schellhaas Past EPFL PhD Students Vanessa Laversenne, Sameer Mohammad Khaleel Nazeeruddin, Emma Charlotta Källstig Past EPFL PhD Students as codirector Philippe Guillaume Coune, Emilda Pino, Elisabeth Anne Dirren, Aurélien Lathuilière, Wojciech Janusz Bobela, Lu Zheng, Cylia Cloé Rochat Courses Methods: from disease models to therapy BIOENG-518 This course will describe methods underlying translational approaches from disease modeling an

Anne-Laure Mahul Mellier

Expertise Cellular Biology: Cell culture of mammalian cell lines (U2OS, N2a, M17, SH-S5Y5, Cos, HeLa, HEK, MCF7), Astrocytic and neuronal primary cultures (hippocampus, cortex, striatum, midbrain) from P0 mouse or rat pups or from E16-E19 mice embryos, iPSC neuronal cultures (proliferation, passaging, differentiation in iNeurons or iDopaminergic neurons), Cellular transfection (DNA plasmid, siRNA, shRNA), Lentiviruses production and infection of neuronal primary cultures or mammalian cell lines, Samples pre

Official source

https://edu.epfl.ch/coursebook/en/neuroscience-from-molecular-mechanisms-to-disease-BIO-480

Moodle Page

http://go.epfl.ch/BIO-480

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Summary

Lectures

Instructors (2)

Bernard Schneider

Anne-Laure Mahul Mellier

Official source

https://edu.epfl.ch/coursebook/en/neuroscience-from-molecular-mechanisms-to-disease-BIO-480

Moodle Page

http://go.epfl.ch/BIO-480

Lectures in this course (22)

Neuroepigenetics: Molecular Mechanisms and Cognitive Implications

Investigates how maternal behavior shapes stress response through epigenetics and discusses genetic vs. epigenetic influences on traits.

Neuroepigenetics: Chromatin Structure & Inheritance

Delves into neuroepigenetics, covering chromatin structure, histone modifications, DNA methylation, and their impact on gene transcription and inheritance.

Genome-wide Association Studies

Explores Genome-wide Association Studies, focusing on identifying genetic variants associated with diseases and the impact on personalized medicine.

Brain Anatomy

Covers the divisions of the nervous system, brain structure, cranial nerves, and brain conditions.

Functional Brain Circuits

Explores brain circuits for sensory perception and external representation, covering thalamus communication, energy-saving mechanisms, inhibitory control, and time perception.

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