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Concept

Tropical disease

Related publications (28)

Heterogeneity in schistosomiasis transmission dynamics

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Francisco Javier Perez Saez

Simple models of disease propagation often disregard the effects of transmission heterogeneity on the ecological and epidemiological dynamics associated with host-parasite interactions. However, for some diseases like schistosomiasis, a widespread parasiti ...

Academic Press Ltd- Elsevier Science Ltd2017

Apparatus and methods for treating excess intraocular fluid

Nikolaos Stergiopoulos, Stéphane Bigler

An ocular drainage system is provided for treating diseases that produce elevated intraocular pressures, such as glaucoma, wherein the system includes an implantable device and an external control unit, the implantable device includes a non-invasively adju ...

2017

Modeling Key Drivers of Cholera Transmission Dynamics Provides New Perspectives for Parasitology

Andrea Rinaldo, Enrico Bertuzzo, Melanie Blokesch, Lorenzo Mari

Hydroclimatological and anthropogenic factors are key drivers of waterborne disease transmission. Information on human settlements and host mobility on waterways along which pathogens and hosts disperse, and relevant hydroclimatological processes, can be a ...

2017

Red squirrels in the British Isles are infected with leprosy bacilli

Stewart Cole, Andrej Benjak, Charlotte Avanzi, Philippe Busso, Jérémie Piton

Leprosy, caused by infection with Mycobacterium leprae or the recently discovered Mycobacterium lepromatosis, was once endemic in humans in the British Isles. Red squirrels in Great Britain (Sciurus vulgaris) have increasingly been observed with leprosy-li ...

American Association for the Advancement of Science2016

Mycobacterium lepromatosis Infections in Nuevo Leon, Mexico

Stewart Cole, Andrej Benjak, Charlotte Avanzi, Philippe Busso, Pushpendra Singh

The frequency of infection caused by the recently described pathogen Mycobacterium lepromatosis is unknown. Here, we describe the demographics, clinical characteristics, and therapeutic outcomes of five lepromatous leprosy patients suffering from M. leprom ...

American Society for Microbiology2015

Institutions, Innovation and Public Health

Viviana Carolina Munoz Tellez de Kieffer

This study concerns the economics of innovation in the area of medical innovation -new diagnostics, medicines and vaccines-, and in particular how innovation contributes to meeting public health needs. Significant advances have taken place in medical scien ...

EPFL2015

Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis

Stewart Cole, Andrej Benjak, Charlotte Avanzi, Philippe Busso, Pushpendra Singh

Mycobacterium lepromatosis is an uncultured human pathogen associated with diffuse lepromatous leprosy and a reactional state known as Lucio's phenomenon. By using deep sequencing with and without DNA enrichment, we obtained the near-complete genome sequen ...

National Academy of Sciences2015

Genome-wide re-sequencing of multidrug-resistant Mycobacterium leprae Airaku-3

Stewart Cole, Jacques Rougemont, Andrej Benjak, Charlotte Avanzi, Philippe Busso, Pushpendra Singh

Genotyping and molecular characterization of drug resistance mechanisms in Mycobacterium leprae enables disease transmission and drug resistance trends to be monitored. In the present study, we performed genome-wide analysis of Airaku-3, a multidrug-resist ...

Wiley-Blackwell2014