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Publication

Mycobacterium lepromatosis Infections in Nuevo Leon, Mexico

Stewart Cole, Andrej Benjak, Charlotte Avanzi, Philippe Busso, Pushpendra Singh
2015
Journal Articles

Abstract

The frequency of infection caused by the recently described pathogen Mycobacterium lepromatosis is unknown. Here, we describe the demographics, clinical characteristics, and therapeutic outcomes of five lepromatous leprosy patients suffering from M. lepromatosis infection in Nuevo Leon, Mexico. Diagnosis was facilitated by a new highly specific PCR procedure.

Official source

https://infoscience.epfl.ch/entities/publication/9fa1bbd7-72fc-4fce-ab98-c987ccbdc3ad

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Stewart Cole, Andrej Benjak, Charlotte Avanzi, Philippe Busso, Pushpendra Singh
2015
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/9fa1bbd7-72fc-4fce-ab98-c987ccbdc3ad

About this result

Related concepts (7)

Leprosy

Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria Mycobacterium leprae or Mycobacterium lepromatosis. Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. This nerve damage may result in a lack of ability to feel pain, which can lead to the loss of parts of a person's extremities from repeated injuries or infection through unnoticed wounds. An infected person may also experience muscle weakness and poor eyesight.

Mycobacterium leprae

Mycobacterium leprae (also known as the leprosy bacillus or Hansen's bacillus) is one of the two species of bacteria that cause Hansen’s disease (leprosy), a chronic but curable infectious disease that damages the peripheral nerves and targets the skin, eyes, nose, and muscles. It is an acid-fast, Gram-positive, rod shaped bacterium and an obligate intracellular parasite, which means, unlike its relative Mycobacterium tuberculosis, it cannot be grown in cell-free laboratory media.

Mycobacterium

Mycobacterium is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis (M. tuberculosis) and leprosy (M. leprae) in humans. The Greek prefix myco- means 'fungus', alluding to this genus' mold-like colony surfaces. Since this genus has cell walls with a waxy lipid-rich outer layer that contains high concentrations of mycolic acid, acid-fast staining is used to emphasize their resistance to acids, compared to other cell types.

Related publications (29)

Mycobacterium lepromatosis Infections in Nuevo Leon, Mexico

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