Jean-Paul Richard KneibExpertise
Cosmology, Gravitational Lensing, Redshift Survey, First Galaxies, Cluster of Galaxies, Fiber-positioner robotic system, Radio Astronomy, Space Sustainibility
Current work
- Former Principal investigator of the SDSS-IV eBOSS project. This is an international project assembling more than 150 participants located mainly in Europe, USA and China. This project will observe 1.5 million galaxy and quasars over 2014-2020 to accurately measure the expansion history of the Universe. * Member of the DESI co
Thibault Adrien KuntzerTeaching & PhD Courses Space mission design and operations EE-585 Space mission design and operations takes you through the necessary concepts to understand a mission mission, from planning to actually flying the spacecraft. We will focus on concepts and see many examples ranging historical probes to very topical missions.
Michaela HirschmannTeaching & PhD PhD Students Patrick Hirling, Jonathan Petersson, Lucie Scharré Courses Astrophysics III : galaxy formation and evolution PHYS-465 Galaxy formation & evolution is about studying how galaxies in our Universe come into existence, how they evolve and what shapes their properties. This course describes the observational facts of galaxies and the various processes of galaxy evolution as seen from theoretical/numerical models. General physics : thermodynamics (English) P
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
David Richard HarveyExpertise
CosmologyDark MatterGalaxy ClustersStrong Gravitational LensingWeak Gravitational Lensing
I am an observational and theoretical astrophysicist at EPFL. My main area of research is dark matter and trying to understand its properties and dynamics. I love to use deep learning in my work and understand how fondation models and generative AI can help us understand the Universe. I am a member of Euclid and ARRAKIHS and the lead of the self interacting dark matter Key Project in Euclid. Outside of my r
Eduardo SanchezTeaching & PhD Past EPFL PhD Students Christian Iseli, Emeka Mosanya, Jean-Michel Puiatti, Dominik Madon, Jacques-Olivier Haenni, Ralph Hoffmann, Yann Thoma, Andres Upegui, Fabien Vannel
Olivier SchneiderAfter his thesis defense in particle physics in 1989 at University of Lausanne, Olivier Schneider joins LBL, the Lawrence Berkeley Laboratory (California), to work on the CDF experiment at the Tevatron in Fermilab (Illinois), first as a research fellow supported by the Swiss National Science Foundation, and later as a post-doc at LBL. He participates in the construction and commissioning of the first silicon vertex detector to operate successfully at a hadron collider; this detector enabled the discovery of the sixth quark, named "top". Since 1994, he comes back to Europe and participates in the ALEPH experiment at CERN's Large Electron-Positron Collider, as CERN fellow and then as CERN scientific staff. He specializes in heavy flavour physics. In 1998, he becomes associate professor at University of Lausanne, then extraordinary professor at the Swiss Institute of Technology Lausanne (EPFL) in 2003, and finally full professor at EPFL in 2010. Having worked since 1997 on the preparation of the LHCb experiment at CERN's Large Hadron Collider, which started operation in 2009, he is now analyzing the first data. He also contributes since 2001 to the exploitation of the data recorded at the Belle experiment (KEK laboratory, Tsukuba, Japan). These two experiments study mainly the decays of hadrons containing a b quark, as well CP violation, i.e. the non-invariance under the symmetry between matter and antimatter.
Yves RevazYves Revaz is a scientist at LASTRO/EPFL. After successful studies in physics at EPFL, he accomplished his PhD entitled: "Dynamics of external regions of spiral galaxies and constraints on the dark matter", at the Geneva Observatory in the galactic dynamics group of Prof. D. Pfenniger. He then moved to the Paris Observatory to work at the LERMA (Laboratory for Studies of Radiation and Matter in Astrophysics) under the supervision of Prof. F. Combes on the understanding of cooling flows in galaxy clusters. He joined LASTRO at EPFL in 2007, where, in collaboration with Pascale Jablonka, he developed a new TreePM/SPH chemo-dynamical code called GEAR, designed to study the chemical evolution of galaxies. His current main research focus on the evolution of dwarf spheroidal galaxies and their link with the cosmology. Yves Revaz is also the author of pNbody, a parallelized python toolbox designed to manipulate large N-body systems.
Kathryn Hess BellwaldKathryn Hess Bellwald received her PhD from MIT in 1989 and held positions at the universities of Stockholm, Nice, and Toronto before moving to the EPFL.Her research focuses on algebraic topology and its applications, primarily in the life sciences, but also in materials science. She has published extensively on topics in pure algebraic topology including homotopy theory, operad theory, and algebraic K-theory. On the applied side, she has elaborated methods based on topological data analysis for high-throughput screening of nanoporous crystalline materials, classification and synthesis of neuron morphologies, and classification of neuronal network dynamics. She has also developed and applied innovative topological approaches to network theory, leading to a powerful, parameter-free mathematical framework relating the activity of a neural network to its underlying structure, both locally and globally.In 2016 she was elected to Swiss Academy of Engineering Sciences and was named a fellow of the American Mathematical Society and a distinguished speaker of the European Mathematical Society in 2017. In 2021 she gave an invited Public Lecture at the European Congress of Mathematicians. She has won several teaching prizes at EPFL, including the Crédit Suisse teaching prize and the Polysphère d’Or.
Murat KuntMurat KUNT was born in Ankara, Turkey, on January 16, 1945. He received his M.S. in Physics and his Ph.D. in Electrical Engineering, both from the Swiss Federal Institute of Technology, Lausanne, Switzerland, in 1969 and 1974 respectively. From 1974 to 1976, he was a visiting scientist at the Research Laboratory of Electronics of the Massachusetts Institute of Technology where he developed compression techniques for Xray images and electronic image files. In 1976, he returned to the Swiss Federal Institute of Technology (EPFL) where, presently, he is Professor of Electrical Engineering and Director of the Signal Processing Institute, one of the largest at EPFL. He conducts teaching and research in digital signal and image processing with applications to modeling, coding, pattern recognition, scene analysis, industrial developments and biomedical engineering. His Laboratory participates in a large number of European projects under various programmes such as Esprit, Eureka, Race, HCM, Commett and Cost. He is the author or the co-author of more than two hundred research papers and fifteen books and holds seven patents. He supervised more than 60 Ph.D. students, some of them being today university professors. He has been the Editor-in-Chief of the Signal Processing Journal for 28 years and a founding member of EURASIP, the European Association for Signal Processing. He is now the Editorin-Chief of Signal, Images and Video Processing journal by Springer and serves as a chairman and/or a member of the Scientific Committees of several international conferences and on the editorial boards of the Proceedings of the IEEE, Pattern Recognition Letters and Traitement du Signal. He was the co-chairman of the first European Signal Processing Conference held in Lausanne in 1980 and the general chairman of the International Image Processing Conference (ICIP'96) held in Lausanne in 1996. He was the President of the Swiss Association for Pattern Recognition from its creation until 1997. He consults for governmental offices including the French General Assembly. He received the gold medal of EURASIP for meritorious services, the IEEE ASSP technical achievement award, the IEEE Third millennium Medal, an honorary doctorate from the Catholic University of Louvain, the technical achievement award of EURASIP and the imaging scientist of the year award of the IS&T and SPIE in 1983, 1997, 2000, 2001, 2003 and 2003 respectively. He retired in June 2008 and has been Professor Emeritus since then.
Please go to: http://lts5www.epfl.ch/kunt.html for more details Oliver MüllerEducation B.Sc. & M.Sc. in Physics | 2008 – 2014 University of Basel Ph.D. in Astronomy | 2014 – 2018 University of Basel Professionals experiences SNSF Postdoctoral Fellow 2018–2021 University of StrasbourgSenior Data Analyst 2021–2022 Google, SwitzerlandSNSF Ambizione Fellow 2022–2022 EPFL
Teaching & PhD Past EPFL PhD Students as codirector Nick Heesters
Awards Amerbach Prize University of Basel 2019 Edith Alice Müller Award Swiss Society for Astrophysics a
Auke IjspeertAuke Ijspeert is a full professor at the EPFL, and head of the Biorobotics Laboratory (BioRob). He has a B.Sc./M.Sc. in physics from the EPFL (1995), and a PhD in artificial intelligence from the University of Edinburgh (1999). He carried out postdocs at IDSIA and EPFL, and at the University of Southern California (USC). He then became a research assistant professor at USC, and an external collaborator at ATR (Advanced Telecommunications Research institute) in Japan. In 2002, he came back to the EPFL as an SNF assistant professor. He was promoted to associate professor in October 2009 and to full professor in April 2016. His primary affiliation is with the Institute of Bioengineering, and secondary affiliation with the Institute of Mechanical Engineering. His research interests are at the intersection between robotics, computational neuroscience, nonlinear dynamical systems, and machine learning. He is interested in using numerical simulations and robots to get a better understanding of sensorimotor coordination in animals, and in using inspiration from biology to design novel types of robots and adaptive controllers. (see for instance Ijspeert et al Science 2007, Ijspeert Science 2014, and Nyakatura et al Nature 2019). He is also investigating how to assist people with limited mobility using exoskeletons and assistive furniture. He is regularly invited to give talks on these topics (e.g. TED talk given at TED Global Geneva, Dec 8 2015). With his colleagues, he has received paper awards at ICRA2002, CLAWAR2005, IEEE Humanoids 2007, IEEE ROMAN 2014, CLAWAR 2015, SAB2018, and CLAWAR 2019. He is an IEEE Fellow, member of the Board of Reviewing Editors of Science magazine, and associate editor for the IEEE Transactions on Medical Robotics and Bionics and for the International Journal of Humanoid Robotics. He has acted as an associate editor for the IEEE Transactions on Robotics (2009-2013) and for Soft Robotics (2018-2021). He was a guest editor for the Proceedings of IEEE, IEEE Transactions on Biomedical Engineering, Autonomous Robots, IEEE Robotics and Automation Magazine, and Biological Cybernetics. He has been the organizer of 7 international conferences (BioADIT2004, SAB2004, AMAM2005, BioADIT2006, LATSIS2006, SSRR2016, AMAM2019), and a program committee member of over 50 conferences.
