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Concept

Matrix (biology)

Related publications (31)

The social nature of mitochondria: Implications for human health

Maria del Carmen Sandi Perez

Sociality has profound evolutionary roots and is observed from unicellular organisms to multicellular animals. In line with the view that social principles apply across levels of biological complexity, a growing body of data highlights the remarkable socia ...

2021

Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis

Matteo Dal Peraro, Françoise Gisou van der Goot Grunberg, Luciano Andres Abriata, Laurence Gouzi Abrami, Béatrice Kunz, Shixu Yan

Capillary morphogenesis gene 2 (CMG2/ANTXR2) is a cell surface receptor for both collagen VI and anthrax toxin. Biallelic loss-of-function mutations in CMG2 lead to a severe condition, hyaline fibromatosis syndrome (HFS). We have here dissected a network o ...

Cell Press - Elsevier2020

Adamts18 Function in Mammary Gland Development

Dalya Ataca

Ovarian hormones control mammary gland development and impinge on breast carcinogenesis acting via their cognate receptors in the luminal epithelium. The extracellular matrix has a key role in physiology and disease but how the two are linked is poorly und ...

EPFL2019

Quantitative intrinsic auto-cathodoluminescence can resolve spectral signatures of tissue-isolated collagen extracellular matrix

Jeffrey Alan Hubbell, Peter Frey, Hans Mattias Larsson, Elif Vardar, Marcin Stefan Zielinski

By analyzing isolated collagen gel samples, we demonstrated in situ detection of spectrally deconvoluted auto-cathodoluminescence signatures of specific molecular content with precise spatial localization over a maximum field of view of 300 mu m. Correlati ...

2019

Decentralized Stochastic Optimization and Gossip Algorithms with Compressed Communication

Martin Jaggi, Sebastian Urban Stich, Anastasiia Koloskova

We consider decentralized stochastic optimization with the objective function (e.g. data samples for machine learning task) being distributed over n machines that can only communicate to their neighbors on a fixed communication graph. To reduce the communi ...

2019

Implementation of Functional Microfluidic Dispensing Tools Enabling Enhanced Control in Extrusion Bioprinting

Ludovic Serex

Inspired from additive manufacturing's success, the structuring of biocompatible materials through bioprinting has become a growing field of research in the past fifteen years. It opened the door to a plethora of applications ranging from the fabrication o ...

EPFL2019

Characterization of a B16-F10 melanoma model locally implanted into the ear pinnae of C57BL/6 mice

Esra Güç

The common experimental use of B16-F10 melanoma cells focuses on exploring their metastatic potential following intravenous injection into mice. In this study, B16-F10 cells are used to develop a primary tumor model by implanting them directly into the ear ...

2018

Slow dynamics in structured neural network models

Samuel Pavio Muscinelli

Humans and some other animals are able to perform tasks that require coordination of movements across multiple temporal scales, ranging from hundreds of milliseconds to several seconds. The fast timescale at which neurons naturally operate, on the order of ...

EPFL2018

Podosomes, But not the Maturation status, Determine the Protease-Dependent 3D Migration in human Dendritic cells

Romain Guiet

Dendritic cells (DC) are professional Antigen-Presenting Cells scattered throughout antigen-exposed tissues and draining lymph nodes, and survey the body for pathogens. Their ability to migrate through tissues, a 3D environment, is essential for an effecti ...

2018

Fighting preterm birth with novel surgical tools and biomaterials engineering

Yannick Robert Devaud

With advances in fetal diagnosis and therapy, fetoscopy has become a good option to treat a series of life threatening diseases like twin-to-twin transfusion syndrome or severe congenital diaphragmatic hernia. The efficacy of fetoscopy for those types of d ...

EPFL2017

Case-Control Discrimination Through Effective Brain Connectivity

Functional and structural connectivity convey different information about the brain. The integration of these different approaches is receiving growing attention from the research community, as it can shed new light on brain functions. This manuscript prop ...

Ieee2017