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Concept

Cross-flow filtration

Related publications (25)

Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation

Christian Heinis, Alessandro Angelini, Alexander Lund Nielsen, Mischa Schüttel, Manuel Leonardo Merz, Xinjian Ji, Anne Sofie Luise Zarda, Ganesh Kumar Mothukuri, Zsolt Bognár, Edward Jeffrey Will

Macrocycles offer an attractive format for drug development due to their good binding properties and potential to cross cell membranes. To efficiently identify macrocyclic ligands for new targets, methods for the synthesis and screening of large combinator ...

Wiley-VCH Verlag GmbH2024

Development of methods for the synthesis of large combinatorial libraries of macrocyclic compounds

Mischa Schüttel

Macrocycles have raised much interest in the pharmaceutical industry due to their ability to bind challenging targets while often still being able to cross membranes to reach intracellular proteins. However, the development of macrocyclic ligands to new di ...

EPFL2023

Homogenization theory captures macroscopic flow discontinuities across Janus membranes

François Gallaire, Pier Giuseppe Ledda, Giuseppe Antonio Zampogna, Kevin Wittkowski

Janus membranes, thin permeable structures with chemical and geometrical asymmetric properties, show great potential in industrial separation processes. Yet the link between the micro- and macro-scale behaviours of these membranes needs to be established r ...

Cambridge University Press2023

Nature-Inspired Stalactite Nanopores for Biosensing and Energy Harvesting

Aleksandra Radenovic, Victor Carle Adrien Boureau, Andrey Chernev, Mukeshchand Thakur, Tzu-Heng Chen, Yunfei Teng, Vasily Artemov, Lucie Navratilova, Nianduo Cai

Nature provides a wide range of self-assembled structures from the nanoscale to the macroscale. Under the right thermodynamic conditions and with the appropriate material supply, structures like stalactites, icicles, and corals can grow. However, the natur ...

Wiley-V C H Verlag Gmbh2023

Pretreatment options for micropollutant abatement before aquifer recharge in drinking water production: Assessment of UV/H2O2 and dense membranes

Robin Wünsch

Micropollutants (MP) such as residues of pharmaceuticals, industrial chemicals or pesticides can be detected in almost all water resources. Various processes can be used to abate them in drinking water treatment, e.g., ozonation, advanced oxidation process ...

EPFL2022

Pressure-Induced Enlargement and Ionic Current Rectification in Symmetric Nanopores

Aleksandra Radenovic, Michal Daniel Macha, Sanjin Marion, Andrey Chernev, Sebastian James Davis

Nanopores in solid state membranes are a tool able to probe nanofluidic phenomena or can act as a single molecular sensor. They also have diverse applications in filtration, desalination, or osmotic power generation. Many of these applications involve chem ...

2020

Benchmarking protocols for the metagenomic analysis of stream biofilm viromes

Tom Ian Battin, Hannes Markus Peter, Massimo Bourquin, Jade Brandani, Meriem Bekliz

Viruses drive microbial diversity, function and evolution and influence important biogeochemical cycles in aquatic ecosystems. Despite their relevance, we currently lack an understanding of their potential impacts on stream biofilm structure and function. ...

PeerJ2019

Electrostatically gated nanofluidic membranes: Technological developments and use of electrochemically polarizable materials

Stefano Silvio Giovanni Varricchio

Solid-state nanoporous membranes able to control ionic flows at the molecular level could have important applications in fields of research such as water filtration, nanomedicine, energy production, drug delivery, and bio-chemical analysis. The ability to ...

EPFL2018

Single-layer MoS2 nanopores as nanopower generators

Aleksandra Radenovic, Andras Kis, Ke Liu, Dumitru Dumcenco, Michael Graf, Dmitry Ovchinnikov, Jiandong Feng

Making use of the osmotic pressure difference between fresh water and seawater is an attractive, renewable and clean way to generate power and is known as 'blue energy'(1-3). Another electrokinetic phenomenon, called the streaming potential, occurs when an ...

Nature Publishing Group2016

Reversible supramolecular modification of surfaces

Negar Moridi

Enzymes are biocatalysts widely used in a large number of industrial biotech processes as they offer clear advantages over their chemical counterparts. Indeed, enzymes often show high substrate selectivity along with elevated turnover rates. Enzymatic cata ...

EPFL2015

Influencing Flow Patterns and Bed Morphology in Open Channels and Rivers by Means of an Air-Bubble Screen

Anton Schleiss, Koen Blanckaert, Violaine Dugué

The ability of a bubble screen to redistribute the flow field and bed morphology in shallow rivers and open channels has been investigated in laboratory experiments. Rising air bubbles generated by a pressurized porous tube situated on the bed induced seco ...

American Society of Civil Engineers2014

A new type of flow structure in cocurrent adiabatic vertically downward air-water flow: Membrane flow

John Richard Thome, Navid Borhani, Marco Milan

A new type of flow structure has been observed in cocurrent adiabatic vertically downward air-water flow and is described here. Membranes, in the form of thin liquid films spanning the channel cross-section and horizontally dividing the gas core were visua ...

Elsevier2014

Characterization of Annular Two-Phase Down Flow Using Non Intrusive Optical Techniques for Flow Patterns, Entrainment, Film Thickness and Velocity Profile

Marco Milan

In this study, adiabatic vertical cocurrent downward air-water flow in an 8.8 mm internal diameter channel was investigated using non intrusive optical techniques. Flow pattern tests were performed to assess the influence of the inlet device, of the test s ...

EPFL2012

A case study of the effect of grain size on the oxygen permeation flux of BSCF disk-shaped membrane fabricated by thermoplastic processing

Stefan Diethelm

Oxygen permeability measurements of Ba0.5Sr0.5Co0.8Fe0.2O3−δ (BSCF) disk shaped membranes fabricated by thermoplastic processing and sintered at different temperatures (1000–1100 °C), showed no influence of the grain size on the oxygen permeation fluxes. T ...

Elsevier2011

Selective Visualization of Fluorescent Sterols in Caenorhabditis elegans by Bleach-Rate-Based Image Segmentation

Daniel Sage

The nematode Caenorhabditis elegans is a genetically tractable model organism to investigate sterol transport. In vivo imaging of the fluorescent sterol, dehydroergosterol (DHE), is challenged by C. elegans' high autofluorescence in the same spectral regio ...

Wiley InterScience2010

New lives for old reverse osmosis (RO) membranes

The overall objective of the present work was to estimate by membrane autopsy the level of performances degradation of old reverse osmosis (RO) membranes/modules in order to envisage their reuse A mechanistic approach using the Spiegler-Kedem-Karchalsky mo ...

2010

Pharmaceuticals and Personal Care Products (PPCPs) in Effluent Matrices: A Survey of Transformation and Removal during Wastewater Treatment and Implications for Wastewater Management

Tamar Kohn

Pharmaceuticals and personal care products (PPCPs) represent pollutants of emerging concern, originating in surface and drinking waters largely from their persistence in wastewater effluent. Accordingly, a wealth of recent investigations has examined PPCP ...

Royal Society of Chemistry2010

Modeling of amino acid nanofiltration by irreversible thermodynamics

Starting from the classical Kedem-Katchalsky model for filtration through membranes, we derive an equation to compute the permeate flux and the rejection of diprotic amino acid compounds. We discuss the influence of the pH, the viscosity and the feed conce ...

2009

Separation properties of supported ionic liquid-polydimethylsiloxane membrane in pervaporation process

Zhaofu Fei

Pervaporation separation properties of water-butan-l-of binary mixtures were measured with the use of three supported liquid membranes at 37 C, namely PDMS, 1-ethenyl-3-ethyl-imidazolium hexafluorophosphate-PDMS, and tetrapropyl-ammonium tetracyanoborate-P ...

2009

Modeling of batch and semi-batch membrane filtration processes

A mathematical frame for modeling batch and semi-batch membrane filtration processes is provided. The approach followed in this work uses the feed concentrations as a basis for the calculations, rather than the concentration factor. A practical computation ...

2009