Dimitrios LignosProf. Lignos joined the École Polytechnique Féderale de Lausanne (EPFL) in 2016 from McGill University in Canada where he was a tenured Associate Professor and a William Dawson Scholar for Infrastructure Resilience. He holds a diploma (National Technical University of Athens, NTUA, 2003), M.S. (Stanford University, 2004) and Ph.D. (Stanford University, 2008). In addition, he was a post-doctoral scientist at Stanford University (2009) and in Kyoto University (2010). Prof. Lignos teaches graduate and undergraduate courses in seismic design, nonlinear behaviour of steel and composite structures as well as supplemental damping systems, Structural Stability, Nonlinear Analysis and Performance-based Earthquake Engineering. His awards for teaching, research and service in Civil Engineering include the 2011 Outstanding Teaching Award (Faculty of Engineering, McGill University), as well as the Outstanding reviewer (2012, 2013) award from ASCE, the 2013 State-of-the-Art in Civil Engineering Award by ASCE and the 2014 Christophe Pierre Award for Research Excellence - Early Career. Just recently, he received the 2019 Walter L. Huber Civil Engineering Research Prize from ASCE for significant contributions in developing state of the art methods to simulate extreme limit states in steel structures.Prof. Lignos is a member of ASCE and the Earthquake Engineering Research Institute. He acts as an Associate Editor for Metal Structures and Seismic Effects of the ASCE Journal of Structural Engineering. He joined the Editorial Board of Earthquake Spectra and Earthquake Engineering and Structural Dynamics International journals. He serves as an acting member of the CEN/TC 250/SC 8/WG 2 and has been selected as a member of the Project Team (PT2) for the Eurocode 8-Part 1 Current Revisions for Steel and Composite Structures. He is also a member of the Canadian Standards Association (CSA) S16 technical committee for Steel Structures. Prof. Lignos is involved as a NEHRP consultant in numerous research-to-practice projects related to the behaviour and nonlinear modelling and analysis of structures applicable to the engineering practice through the Applied Technology Council (ATC). Detailed Curriculum Vitae (last update September 2018)
Jean-François MolinariProfessor J.F. Molinari is the director of the Computational Solid Mechanics Laboratory (http://lsms.epfl.ch) at EPFL, Switzerland. He holds an appointment in the Civil Engineering institute, which he directed from 2013 to 2017, and a joint appointment in the Materials Science institute. He started his tenure at EPFL in 2007, and was promoted to Full Professor in 2012. He is currently an elected member of the Research Council of the Swiss National Science Foundation in Division 2 (Mathematics, Natural and Engineering Sciences), and co editor in chief of the journal Mechanics of Materials. J.F. Molinari graduated from Caltech, USA, in 2001, with a M.S. and Ph.D. in Aeronautics. He held professorships in several countries besides Switzerland, including the United States with a position in Mechanical Engineering at the Johns Hopkins University (2000-2006), and France at Ecole Normale Supérieure Cachan in Mechanics (2005-2007), as well as a Teaching Associate position at the Ecole Polytechnique de Paris (2006-2009). The work conducted by Prof. Molinari and his collaborators takes place at the frontier between traditional disciplines and covers several length scales from atomistic to macroscopic scales. Over the years, Professor Molinari and his group have been developing novel multiscale approaches for a seamless coupling across scales. The activities of the laboratory span the domains of damage mechanics of materials and structures, nano- and microstructural mechanical properties, and tribology. Guillaume AnciauxResearchResearch Topics My research can be decomposed in three main blocks:First, the main goal of my current research is the physical description of contact interactions. I performed numerous studies of this topic using different models from the continuum scale down to atomistic scale. Since atomic phenomena and macroscopic observations are linked, the physics of contact needs the simultaneous consideration of several scales. For instance, plasticity is a theory defined for the macroscopic scale whereas t
Simon GuilloudExpertise
My main domains of research are proof assistants and algorithms for logic-related problems.I also have interests in various areas of computer science and mathematics and their applicability in proof systems such as probabilistic proofs, type theory, quantum computing and more.
Expertise
My main domains of research are proof assistants and algorithms for logic-related problems.I also have interests in various areas of computer science and mathematics and their applicability in proof systems such as
Viktor KuncakViktor Kunčak joined EPFL in 2007, after receiving a PhD degree from MIT. Since then has been leading the Laboratory for Automated Reasoning and Analysis and supervised at least 12 completed PhD theses. His works on languages, algorithms and systems for verification and automated reasoning. He served as an initiator and one of the coordinators of a European network (COST action) in the area of automated reasoning, verification, and synthesis. In 2012 he received a 5-year single-investigator European Research Council (ERC) grant of 1.5M EUR. His invited talks include those at Lambda Days, Scala Days, NFM, LOPSTR, SYNT, ICALP, CSL, RV, VMCAI, and SMT. A paper on test generation he co-authored received an ACM SIGSOFT distinguished paper award at ICSE. A PLDI paper he co-authored was published in the Communications of the ACM as a Research Highlight article. His Google Scholar profile reports an over-approximate H-index of 38. He was an associate editor of ACM Transactions on Programming Languages and Systems (TOPLAS) and served as a co-chair of conferences on Computer-Aided Verification (CAV), Formal Methods in Computer Aided Design (FMCAD), Workshop on Synthesis (SYNT), and Verification, Model Checking, and Abstract Interpretation (VMCAI). At EPFL he teaches courses on functional and parallel programming, compilers, and verification. He has co-taught the MOOC "Parallel Programming" that was visited by over 100'000 learners and completed by thousands of students from all over the world.
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
