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Explores the regulatory environment for quality compliance in drug development and emphasizes the importance of preventative measures and documentation.
Delves into the molecular basis of genetic diseases, discussing specific examples like Phenylketonuria and Haemophilia A, and the development of small molecule drugs for genetic disorders.
Explores the EXSCALATE4COV project, focusing on computational drug discovery for COVID-19 treatments and the collaboration between academia and industry.
Explores the selection and rationale of preclinical animal models in drug development, emphasizing the 10 to 15-year path to a marketed small-molecule drug.
Explores the historical aspects of drug development, regulatory agencies, and ethical principles in pharmacology, emphasizing the importance of informed consent and human subject protection.
Delves into identifying drug targets, ensuring efficacy, and maintaining safety in medical chemistry, covering genetic tests, chirality, stereochemistry, drug resistance, and drug-likeness rules.
Explores the activation, signalling cascades, and regulatory mechanisms of receptor tyrosine kinases, with a focus on disease implications and therapeutic strategies.
Explores the COVID-19 outbreak, its terminology, transmission, severity, and global impact, emphasizing the importance of mitigation strategies and digital epidemiology.
Explores organoids, miniature tissue constructs mimicking living tissues, covering derivation methods, applications, and bridging in vitro and in vivo models.
Explores the regulation of therapeutic products, covering classification, manufacturing, authorization, and advertising, emphasizing the importance of proper authorization for medicines.
Explores kinase inhibitors, enzyme inhibition methods, transition state analog drugs, and the significance of covalent drugs in pharmaceutical research.