Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Kamiar AminianKamiar Aminian received the M.S. degree in electrical engineering in 1982, the Ph.D degree in biomedical engineering in 1989 and the Postgraduate degree on technical computing in 1993 from Ecole Polytechnique Fédérale de Lausanne (EPFL). He was assistant professor (1994-1996) with Sharif University of Technology (Tehran). He joint EPFL in 1996 where he is currently Professor of medical instrumentation and the director of the Laboratory of Movement Analysis and Measurement in the Institute of Bioengineering of EPFL. His research interests include methodologies for human movement monitoring and analysis in real world conditions mainly based on wearable technologies and inertial sensors with emphasis on gait, physical activity and sport. His research aims to perform outcome evaluation in orthopaedics, to improve motor function and intervention programs in aging and patients with movement disorders and pain, and to identify metrics of performance in sport science.
Kamiar Aminian is a member of the International Society of Posture and Gait Research, the Institute of Electrical and Electronics Engineers, the European Society of Movement Analysis in Adults and Children, the Prevention of fall Network Europe, the Intentional Society of Biomechanics and the President of the 3D analysis of the human movement group. He is author or co-author of more than 450 scientific papers published in reviewed journals and presented at international conferences and holds 10 patents related to medical devices.
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ORCID
Bernard SchneiderTeaching & PhD PhD Students Yesica Gloria, Christian Schellhaas Past EPFL PhD Students Vanessa Laversenne, Sameer Mohammad Khaleel Nazeeruddin, Emma Charlotta Källstig Past EPFL PhD Students as codirector Philippe Guillaume Coune, Emilda Pino, Elisabeth Anne Dirren, Aurélien Lathuilière, Wojciech Janusz Bobela, Lu Zheng, Cylia Cloé Rochat Courses Methods: from disease models to therapy BIOENG-518 This course will describe methods underlying translational approaches from disease modeling an
Harald BruneOriginaire de Münich en Allemagne, né en 1961, Harald Brune obtient son diplôme en physique de l'Université Ludwig Maximilians en 1989. Après une thèse en chimie physique à l'Institut Fritz-Haber de la Société Max-Planck à Berlin il obtient son titre de docteur ès sciences en 1992. Dès cela, il rejoint le groupe du Prof. K. Kern à l'Institut de physique expérimentale à l'EPFL. En 1995 il est chercheur invité à Copenhague travaillant en modélisation chez le Prof. J. Nørskov. De retour à l'EPFL, il se voit décerné le prix Latsis EPFL 1996 pour ses études par microscopie à effet tunnel de processus atomiques déterminants la croissance cristalline de couches minces. En 1998 il obtient son habilitation (venia legendi) en Physique et est nommé Maître d'enseignement et de recherche (MER) en nanophysique à l'EPFL. La même année il recoit une offre de Professeur Ordinaire (C4) de l'Université Philipps de Marburg. Début 1999 il réfuse cette offre et accepte un poste de Professeur Extraordinaire à l'EPFL et s'installe au sein de l'Institut de la Physique des Nanostructures. Il est nommé Professeur Ordinaire en 2005. Sa recherche porte sur les propriétés physiques (en particulier le magnétisme et la structure électronique) de nouvelles formes de la matière condensée comme des nanostructures et des couches ultra-minces. Il s'intéresse également à la catalyse hétérogène sur des systèmes inspirés dans leur composition et taille par celle des sites actives dans les enzymes en biologie. Il enseigne la Physique Générale pour ingénieurs, la Physique des matériaux solides pour physiciens, les méthodes expérimentales pour physiciens, ainsi que la Physique des surfaces, interfaces et nanostrcutures à l'école doctorale.
Andrzej KulikExpertise
Experimental Biophysics,nanomechanics,nanomanipulation in 2D and 3D,nanotribology,Atomic Force Microscopy,Optical Tweezers,Photonic Force Microscopy,nano Infrared Spectroscopy (nanoIR),Acoustics,Ultrasound,
Expertise
Experimental Biophysics,nanomechanics,nanomanipulation in 2D and 3D,nanotribology,Atomic Force Microscopy,Optical Tweezers,Photonic Force Microscopy,nano Infrared Spectroscopy (nanoIR),Acoustics,Ultrasound,
Dominique PiolettiDominique Pioletti received his Master in Physics from the Swiss Federal Institute of Technology Lausanne (EPFL) in 1992. He pursued his education in the same Institution and obtained his PhD in biomechanics in 1997. He developed original constitutive laws taking into account viscoelasticity in large deformations. Then he spent two years at UCSD as post-doc fellow acquiring know-how in cell and molecular biology. He was interested in particular to gene expression of bone cells in contact to orthopedic implant. In April 2006, Dominique Pioletti was appointed Assistant Professor tenure-track at the EPFL and is director of the Laboratory of Biomechanical Orthopedics. His research topics include biomechanics and tissue engineering of musculo-skeletal tissues; mechano-transduction in bone; development of orthopedic implant as drug delivery system. Since 2013, he has been promoted to the rank of Associate Professor.
Alexandre TerrierExpertise
BiomechanicsJoint biomechanicsMecano-biologyOrthopaedic researchPatient-specific modellingContinuum mechanicsFinite Element AnalysisExperimental testingStatistical analyses
Expertise
BiomechanicsJoint biomechanicsMecano-biologyOrthopaedic researchPatient-specific modellingContinuum mechanicsFinite Element AnalysisExperimental testingStatistical analyses
Mission
Develop patient-specific models of human joints and their replacement, in parallel with a database of patients, in order to test statistic
Auke IjspeertAuke Ijspeert is a full professor at the EPFL, and head of the Biorobotics Laboratory (BioRob). He has a B.Sc./M.Sc. in physics from the EPFL (1995), and a PhD in artificial intelligence from the University of Edinburgh (1999). He carried out postdocs at IDSIA and EPFL, and at the University of Southern California (USC). He then became a research assistant professor at USC, and an external collaborator at ATR (Advanced Telecommunications Research institute) in Japan. In 2002, he came back to the EPFL as an SNF assistant professor. He was promoted to associate professor in October 2009 and to full professor in April 2016. His primary affiliation is with the Institute of Bioengineering, and secondary affiliation with the Institute of Mechanical Engineering. His research interests are at the intersection between robotics, computational neuroscience, nonlinear dynamical systems, and machine learning. He is interested in using numerical simulations and robots to get a better understanding of sensorimotor coordination in animals, and in using inspiration from biology to design novel types of robots and adaptive controllers. (see for instance Ijspeert et al Science 2007, Ijspeert Science 2014, and Nyakatura et al Nature 2019). He is also investigating how to assist people with limited mobility using exoskeletons and assistive furniture. He is regularly invited to give talks on these topics (e.g. TED talk given at TED Global Geneva, Dec 8 2015). With his colleagues, he has received paper awards at ICRA2002, CLAWAR2005, IEEE Humanoids 2007, IEEE ROMAN 2014, CLAWAR 2015, SAB2018, and CLAWAR 2019. He is an IEEE Fellow, member of the Board of Reviewing Editors of Science magazine, and associate editor for the IEEE Transactions on Medical Robotics and Bionics and for the International Journal of Humanoid Robotics. He has acted as an associate editor for the IEEE Transactions on Robotics (2009-2013) and for Soft Robotics (2018-2021). He was a guest editor for the Proceedings of IEEE, IEEE Transactions on Biomedical Engineering, Autonomous Robots, IEEE Robotics and Automation Magazine, and Biological Cybernetics. He has been the organizer of 7 international conferences (BioADIT2004, SAB2004, AMAM2005, BioADIT2006, LATSIS2006, SSRR2016, AMAM2019), and a program committee member of over 50 conferences.
