Bruno LemaitrePersonal Webpage
http://brunolemaitre.ch
Personal Webpage http://brunolemaitre.ch
Teaching & PhD PhD Students Blandine Ribotta, Yao Tian, Désirée Popelka, Prince Kumar Sah, Siqi Wang, Kenan Krakovic, Nathan Alexandre Klotz Past EPFL PhD Students Sveta Chakrabarti, Olivier Binggeli, Jeremy Keith Herren, Juan Camilo Paredes Escobar, Alfred Chng, Maroun Bou Sleiman, Jan Paul Dudzic, Mario Gonzalo Garcia Arraez, Claudia Melcarne, Alice Marra, Bianca Marie Petrignani, Mark Austin Hanson, Alexia Laurie Carboni Romain GuietExpertise
Development of BioImage Analysis workflows and algorithms to extract quantitative data from microscopy images.BioSample Preparation : in vitro cell, organoid, time-lapse, fixation, staining strategies, actin, mitochondria, fluorescent protein expressionBioImage Acquisition : Widefield, Confocal, Whole Slide Imaging, Super-resolution (SIM, STORM, STED), FRET, FRAP, FLIMBioImage Analysis: Colocalisation analysis, Deconvolution, Time-lapse , Whole Slide ImagingTools & Software: ImageJ/Fiji, QuPath, i
Georges WagnièresGeorges Wagnières received his diploma degree (MSc) in physics from the University of Lausanne, Switzerland, in 1986. He obtained his doctorate in science (PhD) in physics (Biomedical optics) from the Swiss Federal Institute of Technology at Lausanne (EPFL) in 1992 and did a postdoctoral work in the Wellman Laboratories of Photomedicine (Harvard Medical School), Boston, USA, from 1993 to 1994. He also obtained a Master degree in Management of Technology delivered by the Ecole des Hautes Etudes Commerciales (HEC) of Lausanne University and the EPFL in 2001. Georges Wagnières manages a research group active in the fields of: - Detection of early superficial cancers by fluorescence imaging. - Characterization of early superficial cancers by high magnification narrow band imaging. - In vivo and in vitro measurement of the vascular and tissular oxygen concentration by time-resolved luminescence spectroscopy and imaging. - Preclinical and clinical study of new photosensitizers for photodynamic therapy (PDT). - Treatment of neurodegenerative conditions (Alzheimer, Parkinson's diseases) by photobiomodulation. - Preclinical and clinical photodynamic therapy of inflammatory bowel diseases and atheroscerotic plaque. - Improvement of the selective vascular extravasation of chemotherapeutic agents by PDT. - Monitoring the light dosimetry during PDT by fluorescence spectroscopy and imaging. - Monitoring laser treatments of the retina by reflectance imaging. - Light dosimetry and tissue optical spectroscopy. - Radiometry. - Development of light delivery systems for biomedical applications. Georges Wagnières is also co-founder and was chairman of one spin-off companies: - Medlight SA, founded in July 1997, which develops, produces and commercializes light distributors for photodynamic therapy. Georges Wagnières has currently authored more than 235 papers (more than 150 in international journals with review board) and is inventor of 18 patents. He supervised 12 PhD students up to now, and currently teaches biomedical optics and photomedicine in master programs and doctoral schools. In addition, he gives the course entitled "Physique Générale I" to biology first year students registered to the Biology School of the Lausanne's University. MAIN PUBLICATIONS Please visit: https://www.epfl.ch/labs/lifmet/wagnieres/publications/ Demetri PsaltisResearch group
Teaching & PhD PhD Students Victoria Fay, Colin Nikhil Christian Past EPFL PhD Students Wuzhou Song, Alexandre Goy, Julien Cuennet, Ioannis Papadopoulos, Xin Yang, Grégoire Pierre Jean Laporte, Thomas Jean Victor Marie Lanvin, Seyyed Mohammad Hosseini Hashemi, Nicolino Stasio, Morteza Hasani Shoreh, Marilisa Romito, Pooria Hadikhani, Eirini Kakkava, Joowon Lim, Giulia Panusa, Ahmed Bassam Sayed Ayoub Mohamed Ayoub, Amirhossein Saba, Niyazi Ulas Dinç Past EPFL PhD
Maria BrbicMaria Brbic is an assistant professor in computer science at EPFL. Prior to joining EPFL, Maria was a postdoctoral researcher in Computer Science at Stanford University working with Jure Leskovec. She received her PhD degree from University of Zagreb in 2019, while also researching at Stanford University and University of Tokyo. Her research was awarded with the Fulbright Scholarship, L’Oreal UNESCO for Women in Science Scholarship, Branimir Jernej award for outstanding publication in biology and biomedicine, and Josip Loncar Silver Plaque award for the best doctoral dissertation. She has been named a Rising Star in EECS by MIT in 2021. Her research is focused on developing new machine learning methods and applying her methods to advance biomedical research.
Stewart ColeProfessor Stewart Cole is an international authority in bacterial molecular-genetics and genomics. He has made outstanding contributions in several fields including: bacterial anaerobic electron transport; genome analysis of retroviruses and papillomaviruses; antibiotic resistance mechanisms; and the molecular microbiology of toxigenic clostridia. His studies on isoniazid and multidrug resistance in Mycobacterium tuberculosis, together with his pioneering work on the pathogenicity, evolution and genomics of the tubercle and leprosy bacilli, have made him an undisputed leader in the field of mycobacterial research. The findings of his research are of direct relevance to public health and disease-control in both the developing world and the industrialised nations. He has published over 250 scientific papers and review articles, and holds many patents.
Andrea AblasserTeaching & PhD PhD Students Ekaterina Gorbacheva, Iris Arianna Dorschel, Tieliang Gan, Yu Meng Past EPFL PhD Students Simone Margret Haag, Sélène Glück, Marilena Wischnewski, Sophie Rivara, Natasha Samson Courses Immunology - advances and therapeutic implications BIO-479 The students acquire advanced level knowledge regarding the functioning of the (vertebrate) immune system. A strong focus is placed on the molecular mechanisms underlying innate and adaptive immune responses and their impl
Stéphanie LacourStéphanie P. Lacour holds the Bertarelli Foundation Chair in Neuroprosthetic Technology in the School of Engineering at EPFL and leads the Laboratory for Soft Bioelectronic Interfaces. She received her PhD in Electrical Engineering from INSA de Lyon, France, and completed postdoctoral research at Princeton University and the University of Cambridge. She is the recipient of the 2006 MIT TR35, a University Research Fellowship of the Royal Society, European Research Council ERC Starting and POC Grants, and a SNSF-ERC Consolidator Grant. She was elected a 2015 Young Global Leader by the World Economic Forum.
Francesco StellacciFrancesco Stellacci graduated in Materials Engineering at the Politecnico di Milano in 1998 with a thesis on photochromic polymers with Prof. Giuseppe Zerbi and Mariacarla Gallazzi. In 1999 he moved to the Chemistry Department of the University of Arizona for as a post-doc in the group of Joe Perry in close collaboration with the group of Seth Marder. In 2002 he moved to the Department of Materials Science and Engineering at the Massachusetts Institute of Technology as an assistant professor. He was then promoted to associate without (2006) and with tenure (2009). In 2010 he moved to the Institute of Materials at EPFL as a full Professor. He holds the Alcan EP Chair. Francesco was one of the recipients of the Technology Review TR35 "35 Innovator under 35" award in 2005, and the Popular Science Magazine "Brilliant 10" award in 2007. He has been a Packard Fellow starting 2005.
Quy Ong KhacExpertise
Nanoparticle characterizationSurface and interface scienceAnalytical ultracentrifugationCryogenic electron tomographyScanning tunneling microscopy
Current Work
Cryogenic Transmission Electron Tomography (Cryo-ET): Developed Cryo-ET methods as quantitative thermodynamic tools. Studied interaction potentials and other thermodynamic properties of nanoparticles and proteins. Key publications: Ong Q. et al. Materials Horizons, 2022Ekaterina P., Ong, Q. et al. ACS Nano, 2026Analytical Ultracentrifugatio
Bruno Emanuel Ferreira De Sousa CorreiaThroughout my PhD and postdoctoral studies I was trained in world-renowned laboratories and institutions in the United States of America (University of Washington and The Scripps Research Institute). Very early in my scientific career I found out my fascination about protein structure and function. My PhD studies evolved in the direction of immunogen design and vaccine engineering which sparked my interest in the many needs and opportunities in vaccinology and translational research. My efforts resulted in an enlightening piece of work where for the first time, computationally designed immunogens elicited potent neutralizing antibodies. During my postdoctoral studies I joined a chemical biology laboratory at the Scripps Research Institute. In this stage I developed novel chemoproteomics methods for the identification of protein-small molecule interaction sites in complex proteomes. In March 2015, I joined the École Polytechnique Fédérale de Lausanne (EPFL) – Switzerland as a tenure track assistant professor. The focus of my research group is to develop computational tools for protein design with particular emphasis in applying these strategies to immunoengineering (e.g. vaccine and cancer immunotherapy). The activities in my laboratory focus on computational design methods development and experimental characterization of the designed proteins. Our laboratory has been awarded with 2 prestigious research grants from the European Research Council. Lastly, I have been awarded the prize for best teacher of Life sciences in 2019.
Alexandre Louis André PersatExpertise
bacterial biophysics and bioengineeringmicrofluidicscellular biomechanics
Teaching & PhD PhD Students Jann Lukas Ledergerber, Dea Mariette Müller, Marin Paul Geoffroy Marie Ollagnon, Han-Yi Huang, Alice Pellegrino, Shiro Otaki, Chia-Ni Tsai, Po-Long Hsiao Past EPFL PhD Students Lorenzo Anton-Louis Talà, Xavier Pierrat, Tamara Rossy, Alice Cont, Jeremy Wong, Sourabh Monnappa Kuppanda Jafri, Tania Distler Past EPFL PhD Students as codirector Gabriele Gambardella Courses Fluid mechanics (for SV)
Laure MeninExpertise
Mass spectrometryLC-MS / GC-MSBiochemistryProteomicsToxinologyDrug discovery
Teaching & PhD Courses Mass spectrometry, principles and applications CH-728 The goal is to provide students with a complete overview of the principles and key applications of modern mass spectrometry and meet the current practical demand of EPFL researchers to improve structural analsis of molecules. Numerous instrumental aspects of mass spectrometry are described.
Li TangEducation and Training Postdoctoral Fellow, Massachusetts Institute of Technology, 2013 - 2016 Ph.D., University of Illinois at Urbana-Champaign, 2007 - 2012 B.S., Peking University, 2003-2007
