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Concept

Memory and aging

Related publications (28)

Pleiotropic effects of mitochondria in aging

Johan Auwerx, Adrienne Joëlle Laurence Mottis, Yang Li, Tanes Imamura de Lima

Aging is typified by a progressive decline in mitochondrial activity and stress resilience. Here, we review how mitochondrial stress pathways have pleiotropic effects on cellular and systemic homeostasis, which can comprise protective or detrimental respon ...

SPRINGERNATURE2022

Impact of interhemispheric inhibition on bimanual movement control in young and old

Friedhelm Christoph Hummel, Takuya Morishita

Interhemispheric interactions demonstrate a crucial role for directing bimanual movement control. In humans, a well-established paired-pulse transcranial magnetic stimulation paradigm enables to assess these interactions by means of interhemispheric inhibi ...

SPRINGER2022

Treatment and prevention of aging related-disease and/or aging by the inhibition of sphingolipids

Johan Auwerx, Pirkka-Pekka Untamo Laurila

The present invention relates to an inhibitor of sphingolipids for use in the treatment or prevention of an aging related-disease and/or aging. ...

2021

Large-Scale Graph Processing on FPGAs with Caches for Thousands of Simultaneous Misses

Paolo Ienne, Mikhail Asiatici

Efficient large-scale graph processing is crucial to many disciplines. Yet, while graph algorithms naturally expose massive parallelism opportunities, their performance is limited by the memory system because of irregular memory accesses. State-of-the-art ...

IEEE COMPUTER SOC2021

Reward biases spontaneous neural reactivation during sleep

Dimitri Nestor Alice Van De Ville

Sleep favors the reactivation and consolidation of newly acquired memories. Yet, how our brain selects the noteworthy information to be reprocessed during sleep remains largely unknown. From an evolutionary perspective, individuals must retain information ...

Nature Research2021

Differential Susceptibility to the Impact of the COVID-19 Pandemic on Working Memory, Empathy, and Perceived Stress: The Role of Cortisol and Resilience

Maria del Carmen Sandi Perez

There are important individual differences in adaptation and reactivity to stressful challenges. Being subjected to strict social confinement is a distressful psychological experience leading to reduced emotional well-being, but it is not known how it can ...

2021

Learning continuous-time working memory tasks with on-policy neural reinforcement learning

Davide Zambrano

An animals' ability to learn how to make decisions based on sensory evidence is often well described by Reinforcement Learning (RL) frameworks. These frameworks, however, typically apply to event-based representations and lack the explicit and fine-grained ...

2021

Brain structural and functional substrates of ADGRL3 (latrophilin 3) haplotype in attention-deficit/hyperactivity disorder

Erick Jorge Canales Rodriguez

Previous studies have shown that the gene encoding the adhesion G protein-coupled receptor L3 (ADGRL3; formerly latrophilin 3, LPHN3) is associated with Attention-Deficit/Hyperactivity Disorder (ADHD). Conversely, no studies have investigated the anatomica ...

Nature Research2021