Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Rolf GruetterAwards:
1999 Young Investigator Award Plenary Lectureship
, International Society for Neurochemistry
2011 Fellow
, ESMRMB
2011 Teaching Award
, Section Sciences de la Vie, EPFL
Marco MattavelliTeaching & PhD Past EPFL PhD Students Christophe Clerc, Ruohua Zhou, Beilu Shao, Christophe Lucarz, Richard Thavot, Ab Al Hadi Bin Ab Rahman, Endri Bezati, Simone Casale Brunet, Malgorzata Michalska, Ana Angelica Hernandez Lopez, Aurélien Bloch, Mustafa Besirli, Ünsal Öztürk Past EPFL PhD Students as codirector Sylvain Aguirre Courses Systems and architectures for signal processing EE-555 Study of the essential components and implementation technologies of digital signal processing and commu
Diego Ruben BarrettinoDiego Barrettino (S’93–M’98–SM’06) received the Dipl.-Ing. degree in Electronic Engineering from the University of Buenos Aires, Argentina, in 1997, and the Ph.D. degree in Electrical Engineering from the Swiss Federal Institute of Technology Zurich (ETHZ) in 2004.
He worked at Allegro MicroSystems Inc., from 1997 to 2000, where he was an Analog IC Designer of Hall-effect magnetic sensors. From 2000 to 2004, he was a Ph.D. student and Research Assistant at ETHZ, where he designed chemical and mechanical sensors. In 2004, he moved to the USA where he designed biomedical devices first as a Post-Doctoral Research Associate in the University of Washington, and then as an Assistant Professor in the University of Hawaii. In 2006, he returned to Europe where he joined the Swiss Federal Institute of Technology Lausanne (EPFL) as a Senior Research Scientist for the design and development of biosensors using organic nanotransistors. From 2007 to 2009, he was a Senior Lecturer in the University of Glasgow, U.K., and in the University College Cork, Republic of Ireland, where he designed ultra-low power biomedical devices. From 2009 to 2017, he was Full Professor and Head of the Laboratory of Microelectronics, Bioelectronics and Sensor Systems (LMBS) at the University of Applied Sciences of Southern Switzerland (SUPSI), where he designed smart contact lenses and eye implants. In 2017, he joined both the Lucerne University of Applied Sciences (HSLU) and EPFL as a part-time Senior Research Scientist to continue his work on smart sensor systems.
His research interests are in the fields of physical, chemical, and biomedical microsensors; sensor fusion algorithms; analog and mixed-signal IC design; MEMS; embedded systems; avionics and bioelectronics.
Diego Barrettino is a senior member of the Institute of Electrical and Electronics Engineers (IEEE), a member of the American Institute of Aeronautics and Astronautics (AIAA) and a member of the American Association for the Advancement of Science (AAAS).
Nathalie JustExpertise
OncologyMRI, fMRI, fMRS, Diffusion MRS,Animal ModelsAnimal physiologyOptogenetics, Chemogenetics
Current work
-Functional magnetic Resonance imaging in rats and mice -Manganese-enhanced MRI: High Resolution MR Imaging -Functional MR Spectroscopy in small animals - New contrasts for MRI and MRS
Mission
I am interested in all functional aspects of normal and diseased brain from neural activity to metabolism.
-2011-present: EPFL-CIBM AIT Core - Responsible for MR Imaging developments and applications
Giovanni De MicheliExpertise
Design technologies for integrated systems on silicon, such as synthesis, hw/sw codesign and low-power design, as well as systems on heterogeneous platforms including electrical and biological components.
Scientific Director of EcoCloud Center at EPFL
Directing activities towards creating sustainable computation including AI.Designing energy-savvy data centers and edge devices.
More information
Please read http://si2.epfl.ch/~demichel/
Giovanni De Micheli is a research scientist in electronics and Ali MeimandiExpertise
Research interests:Analog and digital circuit designBiomedical circuits and systems
Ali Meimandi received B.Sc degree in electrical engineering from Amirkabir University of Technology(Tehran Polytechnic), Tehran, Iran, and M.Sc. degree in electronic engineering from Politecnico di Milano, Milan, Italy, in 2018 and 2022, respectively. He is a Research Assistant and doctoral candidate in the BioCMOS Interfaces(BCI) Laboratory at école Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.His res
Francesca RodinoExpertise
Electrochemical BiosensorsSensors and Biosensors interfaces | front-end electronicsBiomedical circuits and systems
Francesca Rodino received the B.Sc. and M.Sc. degrees in Biomedical Engineering from the Politecnico di Torino, Turin, Italy, in 2019 and 2022, respectively. She developed her Master's project in the field of cortical neuroprosthesis devices for artificial vision in collaboration with the Integrated Circuits Laboratory (ICLAB) at école Polytechnique Fédérale de Lausanne (EPFL) in Swit
Georges WagnièresGeorges Wagnières received his diploma degree (MSc) in physics from the University of Lausanne, Switzerland, in 1986. He obtained his doctorate in science (PhD) in physics (Biomedical optics) from the Swiss Federal Institute of Technology at Lausanne (EPFL) in 1992 and did a postdoctoral work in the Wellman Laboratories of Photomedicine (Harvard Medical School), Boston, USA, from 1993 to 1994. He also obtained a Master degree in Management of Technology delivered by the Ecole des Hautes Etudes Commerciales (HEC) of Lausanne University and the EPFL in 2001. Georges Wagnières manages a research group active in the fields of: - Detection of early superficial cancers by fluorescence imaging. - Characterization of early superficial cancers by high magnification narrow band imaging. - In vivo and in vitro measurement of the vascular and tissular oxygen concentration by time-resolved luminescence spectroscopy and imaging. - Preclinical and clinical study of new photosensitizers for photodynamic therapy (PDT). - Treatment of neurodegenerative conditions (Alzheimer, Parkinson's diseases) by photobiomodulation. - Preclinical and clinical photodynamic therapy of inflammatory bowel diseases and atheroscerotic plaque. - Improvement of the selective vascular extravasation of chemotherapeutic agents by PDT. - Monitoring the light dosimetry during PDT by fluorescence spectroscopy and imaging. - Monitoring laser treatments of the retina by reflectance imaging. - Light dosimetry and tissue optical spectroscopy. - Radiometry. - Development of light delivery systems for biomedical applications. Georges Wagnières is also co-founder and was chairman of one spin-off companies: - Medlight SA, founded in July 1997, which develops, produces and commercializes light distributors for photodynamic therapy. Georges Wagnières has currently authored more than 235 papers (more than 150 in international journals with review board) and is inventor of 18 patents. He supervised 12 PhD students up to now, and currently teaches biomedical optics and photomedicine in master programs and doctoral schools. In addition, he gives the course entitled "Physique Générale I" to biology first year students registered to the Biology School of the Lausanne's University. MAIN PUBLICATIONS Please visit: https://www.epfl.ch/labs/lifmet/wagnieres/publications/ Show more