Concept

Vaccine

A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease. The safety and effectiveness of vaccines has been widely studied and verified.

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https://en.wikipedia.org/wiki/Vaccine

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Official source

https://en.wikipedia.org/wiki/Vaccine

About this result

Ontological neighbourhood

Health sciences

Infectious diseases: Topics in infectious diseases

Related courses (20)

MSE-471: Biomaterials (pour MX)

BIO-310: Immunology

MSE-212: Biology for engineers

Related lectures (32)

COVID-19: Virological Situation, Variants, and Vaccine Technologies

Covers the virological situation of COVID-19, new variants, and vaccine technologies.

Basic Principles of Vaccination MOOC: Introduction to immunology (part 2)

Covers the history and principles of vaccination, types of vaccines, immune response, and herd immunity.

An Overview of Vaccines

Covers precision tumor recognition, challenges in T cell therapy, vaccination impact, history, types, and examples of vaccines, immune response, and COVID-19 vaccine types.

Related publications (18)

Baseline interferon signaling in monocytes and antibody-mediated innate activation are associated with reactogenicity to mRNA vaccines

The local and systemic symptoms that follow vaccination, collectively referred to as reactogenicity, are common, yet the mechanisms underlying individual variability remain poorly understood. Through longitudinal immune profiling of vaccinated individuals and mechanistic studies in mice, we identified key immunological determinants of reactogenicity induced by mRNA vaccines. Systemic adverse events were associated with stronger interferon and pro-inflammatory responses after the second dose of a COVID-19 mR

American Association for the Advancement of Science2026

Target trial emulation without matching: a more efficient approach for evaluating vaccine effectiveness using observational data

Real-world vaccine effectiveness has increasingly been studied using matching-based approaches, particularly in observational cohort studies that follow the target trial emulation framework. Although matching is appealing in its simplicity, it has important limitations in terms of clarity of the target estimand and the precision with which it is estimated. Moreover, defining causal estimands of vaccine effectiveness requires care, because vaccine uptake often occurs over calendar time when infection dynamic

Ovid Technologies (Wolters Kluwer Health)2026

A simple and powerful test of vaccine waning

Determining whether vaccine efficacy wanes is important for individual and public decision making. Yet, quantification of waning is a subtle task. The classical approaches cannot be interpreted as measures of declining efficacy unless we impose unreasonable assumptions. Recently, formal causal estimands designed to quantify vaccine waning have been proposed. These estimands can be bounded under weaker assumptions, but the bounds are often too wide to make claims about the presence of waning. We propose a di

Oxford University Press (OUP)2026

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Related concepts (31)

Vaccination

Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating the body's adaptive immunity, they help prevent sickness from an infectious disease. When a sufficiently large percentage of a population has been vaccinated, herd immunity results. Herd immunity protects those who may be immunocompromised and cannot get a vaccine because even a weakened version would harm them.

Infection

An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune systems. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response.

BCG vaccine

Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). It is named after its inventors Albert Calmette and Camille Guérin. In countries where tuberculosis or leprosy is common, one dose is recommended in healthy babies as soon after birth as possible. In areas where tuberculosis is not common, only children at high risk are typically immunized, while suspected cases of tuberculosis are individually tested for and treated.