Henning Paul-Julius StahlbergMission
We use high-resolution cryo-electron microscopy to study neurodegeneration and other protein systems. We also develop novel imaging technology in the areas of electron microscopy hardware and applications, sample preparation, data collection schemes, and data analysis software systems. The Stahlberg group is supported by the University of Lausanne, Faculty of Medicine and Biology, and by the EPFL, Faculty of Basic Sciences, Physics Institute. The LBEM is a research laboratory of both UNIL and EPFL.
Stewart ColeProfessor Stewart Cole is an international authority in bacterial molecular-genetics and genomics. He has made outstanding contributions in several fields including: bacterial anaerobic electron transport; genome analysis of retroviruses and papillomaviruses; antibiotic resistance mechanisms; and the molecular microbiology of toxigenic clostridia. His studies on isoniazid and multidrug resistance in Mycobacterium tuberculosis, together with his pioneering work on the pathogenicity, evolution and genomics of the tubercle and leprosy bacilli, have made him an undisputed leader in the field of mycobacterial research. The findings of his research are of direct relevance to public health and disease-control in both the developing world and the industrialised nations. He has published over 250 scientific papers and review articles, and holds many patents.
Coralie BussoExpériences professionnelles Apprentie Laborantine 2001–2004 CMU Dpt. de physiologie cellulaire et métabolisme
RechercheCentrosomes promote timely mitotic entry in C. ele Dev Cell. 2007 Apr;12(4):531-41.Centrosomes promote timely mitotic entry in C. elegans embryos.Hachet V, Canard C, Gönczy P.SourceSwiss Institute for Experimental Cancer Research (ISREC), and School of Life Sciences, Swiss Federal Institute of Technology (EPFL), CH-1066 Lausanne, Switzerland.AbstractSeveral mitotic regulators, including
Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Kumar Varoon AgrawalExpertise
Prof. Kumar Varoon Agrawal leads research at EPFL on advanced membrane materials and processes for energy-efficient molecular separations. His work focuses on atomically thin porous graphene film, and two-dimensional zeolite & metal–organic framework membranes that enable selective transport of gases and ions, with applications in carbon capture, hydrogen purification, ammonia separation, and resource recovery. By combining materials chemistry, nanofluidics, transport phenomena, atomistic simulati
Alessandro BarducciTeaching & PhD Past EPFL PhD Students as codirector Salvatore Assenza, Duccio Malinverni
Didier TronoAfter obtaining an M.D. from the University of Geneva and completing a clinical training in pathology, internal medicine and infectious diseases in Geneva and at Massachusetts General Hospital in Boston, Didier Trono embarked in a scientific career at the Whitehead Institute for Biomedical Research of MIT. In 1990, he joined the faculty of the Salk Institute for Biological Studies to launch a center for AIDS research. He moved back to Europe seven years later, before taking the reins of the newly created EPFL School of Life Sciences, which he directed from 2004 to 2012. He is now actively engaged in the efforts of Switzerland to integrate new technologies in the fields of precision medicine and personalized health.
Marcel DrabbelsDr. Marcel Drabbels studied experimental physics at the University of Nijmegen (the Netherlands) and in 1993 obtained his Ph.D. at that same university. He then moved to the University of California at Santa Barbara where he studied the dynamics of highly vibrationally excited molecules and developed a new detection technique to investigate the photodissociation of molecules. When he returned to the Netherlands in 1996 he joined the FOM Institute for Atomic and Molecular Physics in Amsterdam where he worked on the development of new types of infrared imaging and streak cameras. In 1997 Dr. Drabbels was awarded a fellowship of the Royal Dutch Academy of Sciences and he moved to the Free University of Amsterdam where he studied the collision dynamics of molecules and initiated photodissociation experiments using ultrafast lasers. In October 1998 he was appointed as senior scientist at the EPFL where he studies the spectroscopy and dynamics of nanoscale systems. In March 2021 he was promoted to titular professor.
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