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Concept

Inbreeding depression

Related publications (27)

Vulnerability of conditional NCAM-deficient mice to develop stress-induced behavioral alterations

Maria del Carmen Sandi Perez

Previous studies in rodents showed that chronic stress induces structural and functional alterations in several brain regions, including shrinkage of the hippocampus and the prefrontal cortex, which are accompanied by cognitive and emotional disturbances. ...

2012

Acute Hypoglycemia Induces Retinal Cell Death in Mouse

Background: Glucose is the most important metabolic substrate of the retina and maintenance of normoglycemia is an essential challenge for diabetic patients. Glycemic excursions could lead to cardiovascular disease, nephropathy, neuropathy and retinopathy. ...

Public Library of Science2011

The Interplay between Cytidine Deaminases, HIV and Domesticated Genetic Parasites

"There is more virus in us than us in us". John Coffin's famous sentence illustrates that particular nucleic acid sequences related to exogenous viruses, called retrotransposons, constitute almost half of the human genome and largely exceeds the amount of ...

EPFL2010

Dualities in plant tolerance to pollutants and their uptake and translocation to the upper plant parts

Jean-Paul Schwitzguebel

There is a duality in plant tolerance to pollutants and its response to the pollutants’ stress. On the one hand some plants, (hyper)tolerant to heavy metals, are able to hyperaccumulate these metals in shoots, which could be beneficial for phytoremediation ...

2009

Structural Efficiency of Percolated Landscapes in Flow Networks

Paolo De Los Rios

The large-scale structure of complex systems is intimately related to their functionality and evolution. In particular, global transport processes in flow networks rely on the presence of directed pathways from input to output nodes and edges, which organi ...

Public Library of Science2008

Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo

Nicole Déglon

Huntington's disease (HD) results from an abnormal polyglutamine extension in the N-terminal region of the huntingtin protein. This mutation causes preferential degeneration of striatal projection neurons. We previously demonstrated, in vitro, that dopamin ...

Elsevier2008

Predicting mask distortion, clogging and pattern transfer for stencil lithography

Jürgen Brugger, Marc Antonius Friedrich van den Boogaart

One of the ultimate tasks for stencil lithography is the ability to fabricate arrays of structures with controlled dimensions on the nanometer scale precisely positioned on a suitable surface. The race to shrink feature sizes requires the limits of convent ...

2007