Bernard SchneiderTeaching & PhD PhD Students Yesica Gloria, Christian Schellhaas Past EPFL PhD Students Vanessa Laversenne, Sameer Mohammad Khaleel Nazeeruddin, Emma Charlotta Källstig Past EPFL PhD Students as codirector Philippe Guillaume Coune, Emilda Pino, Elisabeth Anne Dirren, Aurélien Lathuilière, Wojciech Janusz Bobela, Lu Zheng, Cylia Cloé Rochat Courses Methods: from disease models to therapy BIOENG-518 This course will describe methods underlying translational approaches from disease modeling an
Didier TronoAfter obtaining an M.D. from the University of Geneva and completing a clinical training in pathology, internal medicine and infectious diseases in Geneva and at Massachusetts General Hospital in Boston, Didier Trono embarked in a scientific career at the Whitehead Institute for Biomedical Research of MIT. In 1990, he joined the faculty of the Salk Institute for Biological Studies to launch a center for AIDS research. He moved back to Europe seven years later, before taking the reins of the newly created EPFL School of Life Sciences, which he directed from 2004 to 2012. He is now actively engaged in the efforts of Switzerland to integrate new technologies in the fields of precision medicine and personalized health.
Quentin BarraudExpertise
Translational neuroscience · Neuromodulation · Spinal cord injury & Parkinson’s disease · Multi-omics (single-cell, spatial transcriptomics, 3D cleared-tissue imaging) · Preclinical platform management
Mission
To develop, coordinate, and supervise the preclinical activities of .NeuroRestore at EPFL, integrating innovative neuromodulation, gene therapy, and multi-omic strategies. To ensure regulatory compliance of all animal work, support scientific teams in experimental design, and build bridges b
Georges WagnièresGeorges Wagnières received his diploma degree (MSc) in physics from the University of Lausanne, Switzerland, in 1986. He obtained his doctorate in science (PhD) in physics (Biomedical optics) from the Swiss Federal Institute of Technology at Lausanne (EPFL) in 1992 and did a postdoctoral work in the Wellman Laboratories of Photomedicine (Harvard Medical School), Boston, USA, from 1993 to 1994. He also obtained a Master degree in Management of Technology delivered by the Ecole des Hautes Etudes Commerciales (HEC) of Lausanne University and the EPFL in 2001. Georges Wagnières manages a research group active in the fields of: - Detection of early superficial cancers by fluorescence imaging. - Characterization of early superficial cancers by high magnification narrow band imaging. - In vivo and in vitro measurement of the vascular and tissular oxygen concentration by time-resolved luminescence spectroscopy and imaging. - Preclinical and clinical study of new photosensitizers for photodynamic therapy (PDT). - Treatment of neurodegenerative conditions (Alzheimer, Parkinson's diseases) by photobiomodulation. - Preclinical and clinical photodynamic therapy of inflammatory bowel diseases and atheroscerotic plaque. - Improvement of the selective vascular extravasation of chemotherapeutic agents by PDT. - Monitoring the light dosimetry during PDT by fluorescence spectroscopy and imaging. - Monitoring laser treatments of the retina by reflectance imaging. - Light dosimetry and tissue optical spectroscopy. - Radiometry. - Development of light delivery systems for biomedical applications. Georges Wagnières is also co-founder and was chairman of one spin-off companies: - Medlight SA, founded in July 1997, which develops, produces and commercializes light distributors for photodynamic therapy. Georges Wagnières has currently authored more than 235 papers (more than 150 in international journals with review board) and is inventor of 18 patents. He supervised 12 PhD students up to now, and currently teaches biomedical optics and photomedicine in master programs and doctoral schools. In addition, he gives the course entitled "Physique Générale I" to biology first year students registered to the Biology School of the Lausanne's University. MAIN PUBLICATIONS Please visit: https://www.epfl.ch/labs/lifmet/wagnieres/publications/ Pierre MagistrettiPierre J. Magistretti is an internationally-recognized neuroscientist who has made significant contributions in the field of brain energy metabolism. His group has discovered some of the cellular and molecular mechanisms that underlie the coupling between neuronal activity and energy consumption by the brain.
This work has considerable ramifications for the understanding of the origin of the signals detected with the current functional brain imaging techniques used in neurological and psychiatric research (see for example Magistretti et al, Science, 283: 496 497, 1999). He is the author of over 100 articles published in peer-reviewed journals.
He has given over 80 invited lectures at international meetings or at universities in Europe and North America, including the 2000 Talairach Lecture at the Functional Mapping of the Human Brain Conference. In November 2000 he has been a Mc Donnel Visiting Scholar at Washington University School of Medicine.
Pierre J. Magistretti is the President-Elect (2002 2004) of the Federation of European Neuroscience Societies (FENS) which has a membership of over 15000 European neuroscientists. He has been first president of the Swiss Society for Neuroscience (1997-1999) and the first Chairman of the Department of Neurosciences of the University of Lausanne (1996 1998).
Pierre J. Magistretti is Professor of Physiology (since 1988) at the University of Lausanne Medical School. He has been Vice-Dean of the University of Lausanne Medical School from 1996 to 2000. Pierre Magistretti, is Director of the Brain Mind Institute at EPFL and Director of the Center for Psychiatric Neuroscience of the University of Lausanne and CHUV. He is also Director of the NCCR SYNAPSY "the synaptic bases of mental diseases".
POSITIONS AND HONORS
MAIN POSITION HELD
1988-2004 Professor of Physiology, University of Lausanne Medical School
1996-2000 Vice-Dean for Preclinical Departments, University of Lausanne Medical School
2001-2004 Chairman, Department of Physiology, University of Lausanne Medical School
2004-present Professor and Director, Center for Psychiatric Neuroscience, Department of Psychiatry, University of Lausanne Medical School and Hospitals (UNIL-CHUV) (Joint appointment with EPFL)
2005-2008 Professor and Co-Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne (Joint appointment with UNIL-CHUV)
2007-present Chairman of the Scientific Advisory Board of Centre dImagerie Biomédicale (CIBM), an Imaging Consortium of the Universities, University Hospitals of Lausanne and Geneva and of Ecole Polytechnique Fédérale de Lausanne
2008-present Professor and Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne Joint appointment with UNIL-CHUV)
2010-present Director, National Center for Competence in Research (NCCR)
The synaptic bases of mental diseases of the Swiss National Science Foundation
2010-present Secretary General, International Brain Research Organization (IBRO)
MAIN HONORS AND AWARDS
1997 Recipient of the Theodore-Ott Prize of the Swiss Academy of Medical Sciences
2001 Elected Member of Academia Europaea
2001 Elected Member of the Swiss Academy of Medical Sciences, ad personam
2002 Recipient of the Emil Kraepelin Guest Professorship, Max Planck Institute für Psychiatry, Münich
2006 Elected Professor at Collège de France, Paris, International Chair 2007-2008
2009 Goethe Award for Psychoanalytic Scholarship, Canadian Psychological Association
2011 Camillo Golgi Medal Award, Golgi Fondation
2011 Elected Member of the American College of NeuroPsychopharmacology (ACNP)
Romain ZuffereyTeaching & PhD Courses Biology for engineers MSE-212 This course consists of an introduction to biology and more particularly to biology as a multidisciplinary field, emphasizing natural examples of materials engineering. It should therefore allow engineering students to find inspiration from biology in future materials research problems. Cellular biology and biochemistry for engineers BIO-105 Basic course in biochemistry as well as cellular and molecular biology for non-life
Christophe MoserDr. Christophe Moser is
Associate Professor of Microengineering and Industrial Relations
at the Swiss Federal Institute of Technology in Lausanne. He was the co-founder and CEO of
Ondax,Inc
for ten years prior to joining EPFL. During this decade, he raised $15 million from corporate and venture capital sources to fund volume production of thick holographic components in glass and develop devices enabled by these components such as tunable add-drop multiplexers for telecommunications, ultra-narrowband notch filters for low frequency Raman systems, high power semi-conductor frequency-narrowed pumps for fiber lasers, single frequency fixed and tunable lasers for sensing and femtosecond pulse compressors for micro-machining applications. Dr. Moser has a Ph.D. in Electrical Engineering from the California Institute of Technology, a minor in finance and a bachelor degree in Physics from EPFL.
He is the co-inventor of 24 patents, 14 peer reviewed scientific publications, 9 IEEE proceedings and a book chapter.
Private interests include tennis, running, ski, basketball and family excursions.
2010: Associate Professor, EPFL, faculty
Science Technique Ingenieur.
2000-2010: co-founder, CEO Ondax, Inc.
1995-2000: Graduate Research Assistant,
California Institute of Technology.
1993-1995: Engineering Project manager ,
TESA.
1988-1993: Bachelor candidate in Physics, EPFL.
MAIN PUBLICATIONS:
Moser C., Havermeyer F,.Ultra-narrowband tunable laserline notch filter, Appl. Phys. B, 95 (3), pp 597-601, 2009.
Moser C. ,Ho L., Havermeyer F,. Self-aligned Non-dispersive External Cavity Tunable Laser, 16 (21), 16691-16696 Optics Express, 2008.
Steckman, GJ , Moser C. et al. Volume holographic grating wavelength stabilized laser diodes, IEEE J. Of Selected Topics in Quantum Electronics, (13), 672-678, 2007.
Buse K, Havermeyer F, Liu W., Moser C, Psaltis D. Holographic Filters , Book Chapter Photorefractive Materials and their Applications, 2005.
Havermeyer, F; Liu, WH; Moser, C, et al. Volume holographic grating-based continuously tunable optical filter , Opt. Eng. 43 (9), 2017-2021, 2004.
Moser C., Maravic I., Schupp B., Adibi A, Psaltis D, Diffraction efficiency of localized holograms in doubly doped LiNbO3 crystals, Opt. Lett. 25: (17),1243-1245, 2000. Ute KochExpertise
SCIENTIFIC EXPERTISESCurrent Molecular Biology and Cloning, Developmental Biology, Cellular and Molecular Immunology, Lymphocyte Maturation and Lineage Commitment, Thymic Selection, Hematopoietic Stem Cell Biology, Bone Marrow Transplantation, Graft-versus-Host Disease, Skin Transplantation, T Lymphocyte Subset Induction (Th1 - Th2, Cytokine Regulation), Extensive Knowledge in Flow CytometryIT SKILLSMicrosoft-Office: Word, Excel, PowerPoint.File Maker Pro: Database design and management.Flow cytom
Gioele La MannoTeaching & PhD PhD Students Albert Dominguez Mantes, Xinyi Huang, Laura Lapeña Gil, Alessandro Valente, Luca Fusar Bassini, Hao-An Hsiung, Alireza Gargoorimotlagh, Morgane Alice Storey, Rosan Martine Hans, María Cristina Loureiro Casalderrey, Lada Polyakova Past EPFL PhD Students Alex Russell Lederer, Irina Khven Past EPFL PhD Students as codirector Alexandre Coudray, Alex Russell Lederer, Halima Hannah Emilie Schede, Irina Khven Courses Biological data science I: statistical learning BIOENG-210
Marion LeleuExpertise
Bioinformatics, Genomics, High-Throughput Sequencing, Data Mining
Mission
Provide advanced and personalised support and consulting in bioinformatics and biostatistics for the scientific community of EPFL, UNIL, and other Institutes.Her main areas of interest and expertise include but are not limited to, genomics, transcriptomics and epigenetics, with a strong interest in integrating multiple modalities, and choosing the appropriate statistical models, to gain a comprehensive understanding of compl
Sandrine GerberSandrine Gerber studied chemistry at the "Ecole Nationale Supérieure de Chimie de Paris" in France, where she obtained a diploma of chemical engineer in 1993. The same year she obtained a DEA (Master degree) of organic chemistry at the University Pierre et Marie Curie (Paris VI, France). From 1993 to 1996 she did a PhD in organic chemistry under the supervision of Prof. Jean-Pierre Genêt at the Ecole Nationale Supérieure de Chimie de Paris. In 1996, she moved to University of Lausanne for a post-doctoral stay under the supervision of Prof. Pierre Vogel. In 1998, she was appointed Maître-Assistante at the Institute of Organic Chemistry in the University of Lausanne. In 2003, she obtained the habilitation to direct research from the University Pierre et Marie Curie (Paris VI, France). The same year, she was appointed scientific adjunct at the EPFL and senior scientist (Maître d'Enseignement et de Recherche) in 2006. In December 2014, she was promoted to titular professor. Since September 2007, Sandrine Gerber is deputy to the director of the Institute of Chemical Sciences and Engineering (ISIC). She is also member of the Board of Directors of the Swiss Chemical Society. Since 2007, Sandrine Gerber is part-time lecturer at the university of Fribourg. She was awarded the Prize Eugene Schueller in 1997, the Prize Dufour for prospective organic chemistry in 2005 and the Werner Prize 2010. She also received a special mention in recognition of exceptional quality of pedagogic competencies in the teaching of basic sciences, given by the Direction of the School of Biology and Medicine from the University of Lausanne, in 2013. In October 2018, she will receive the Prize for Excellence in Teaching from the section of Chemistry and Chemical Engineering.
Lucia Baldi Unser01/2021 - present Deputy to the Associate VP for Research / Deputy to the Associate VP for Centers & Platforms, EPFL06/2017 - 12/2020 Deputy to the Dean, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne ;01/2015 - 11/2017 Lecturer/Communication and outreach manager at the School of Life Sciences, EPFL04/1998 - 03/2015: Research and Teaching Associate/Lecturer, Laboratory of Cellular Biotechnology, School of Life Sciences; 01/1994 - 07/1997: Visiting Fellow, Laboratory of Immunoregulation, NIAID, NIH, Bethesda, Maryland, USA;1991 - 1994: Research Fellow, Laboratory of Pediatric Oncology, G. Gaslini Scientific Institute, Genova, Italy;1987 - 1990: Research Fellow, Clinical Immunology and Immunogenetics Dept., Nat. Inst. for Cancer Research, Genova, Italy.
Kevin SivulaSee webpage for more info limno.epfl.ch
Teaching & PhD PhD Students Odile Louise Andres, Arthur Eliot Bouchez, Benjamin Goldman, Nicolas Johannes Diercks, Aurélie Fanny Marie Célérien, Jiajun Li, Louise Marie Foltzer-De Cian, Melanie Victoria Johanning, Nils William Laurent Golay Past EPFL PhD Students Andrea Gasperini, Pauline Bornoz, Xavier Adrian Jeanbourquin, Xiaoyun Yu, Mathieu Steven Prévot, Muhammad Aiman Bin Rahmanudin Hamdan, Nhât-Tân Vuong, Yongpeng Liu, Arvindh Sekar, Barbara Alexandra Primera
Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Tobias KippenbergTobias J. Kippenberg is Full Professor of Physics at EPFL and leads the Laboratory of Photonics and Quantum Measurement. He obtained his BA at the RWTH Aachen, and MA and PhD at the California Institute of Technology (Caltech in Pasadena, USA). From 2005- 2009 he lead an Independent Research Group at the MPI of Quantum Optics, and is at EPFL since. His research interest are the Science and Applications of ultra high Q microcavities; in particular with his research group he discovered chip-scale Kerr frequency comb generation (Nature 2007, Science 2011) and observed radiation pressure backaction effects in microresonators that now developed into the field of cavity optomechanics (Science 2008). Tobias Kippenberg is alumni of the “Studienstiftung des Deutschen Volkes”. For his invention of “chip-scale frequency combs” he received he Helmholtz Price for Metrology (2009) and the EFTF Young Investigator Award (2010). For his research on cavity optomechanics, he received the EPS Fresnel Prize (2009). In addition he is recipient of the ICO Prize in Optics (2014), the Swiss National Latsis award (2015), the German Wilhelm Klung Award (2015) and ZEISS Research Award (2018). He is fellow of the APS and OSA, and listed since 2014 in the Thomas Reuters highlycited.com in the domain of Physics. EDUCATION 2009: Habilitation (Venia Legendi) in Physics, Ludwig-Maximilians-Universität München 2004: PhD, California Institute of Technology (Advisor Professor Kerry Vahala) 2000: Master of Science (Applied Physics), California Institute of Technology 1998: BA in Physics, Technical University of Aachen (RWTH), Germany 1998: BA in Electrical Engineering, Technical University of Aachen (RWTH), Germany ACADEMIC POSITIONS 2013 - present: Full Professor EPFL 2010 - 2012: Associate Professor EPFL 2008 - 2010: Tenure Track Assistant Professor, Ecole Polytechnique Federale de Lausanne 2007 - present: Marie Curie Excellent Grant Team Leader, Max Planck Institute of Quantum Optics (Division of Prof.T.W. Hänsch) 2005 - present: Leader of an Independent Junior Research Group, Max Planck Institute 2005- present: Habilitant (Prof. Hänsch) Ludwig-Maximilians-Universität (LMU) 2005-2006: Postdoctoral Scholar, Center for the Physics of Information, California Institute of Technology 2000-2004: Graduate Research Assistant, California Institute of Technology PRIZES AND HONORS: ZEISS Research Award 2018 Fellow of the APS 2016 Klung-Wilhelmy Prize 2015 Swiss Latsis Prize 2014 Selected Thomson Reuters Highly Cited Researcher in Physics, 2014/2015 ICO Prize, 2013 EFTF Young Scientist Award (for "invention of microresonator based frequency combs") 2010 Fresnel Prize of the European Physical Society (for contributions to Optomechanics) 2009 Helmholtz Prize for Metrology (for invention of the monolithic frequency comb) 2009 1st Prize winner of the EU Contest for Young Scientists, Helsinki, Finland. Sept. 1996 Jugend forscht 1st Physics Prize at the German National Science Contest May 1996 FELLOWSHIPS Fellow of the German National Merit Foundation ("Studienstiftung des Deutschen Volkes") 1998-2002 Member of the Daimler-Chysler-Fellowship-Organization 1998-2002 Dr. Ulderup Fellowship 1999-2000 RESEARCH INTERESTS Experimental and theoretical research in photonics, notably high Q optical microcavities and their use in cavity quantum optomechanics and frequency metrology PUBLICATIONS AND OFTEN CITED METRICS*: >70 Publications in peer reviewed journals Researcher Google Profile: http://scholar.google.ch/citations?user=PRCbG2kAAAAJ&hl=en h-Index 54 (Google scholar H: 64, >25,000 citations) Thomson Reuters/Claravite List of Highly Cited Researchers (2014,2015,2016,2017) careful in its use: https://www.aps.org/publications/apsnews/201411/backpage.cfm KEY PUBLICATIONS AND REVIEWS: A. Ghadimi, et al. Elastic strain engineering for ultra high Q nanomechanical oscillators Science, (2018) Trocha, et al. Ultrafast distance measurements using soliton microresonator frequency combs Science, Vol. 359 (2018) [joint work with C. Koos] Pablo-Marin et al. Microresonator-based solitons for massively parallel coherent optical communications Nature (2017) [joint work with C. Koos] V. Brasch, et al. Photonic chip-based optical frequency comb using soliton Cherenkov radiation. Science, vol. 351, num. 6271 (2015) Aspelmeyer, M., Kippenberg, T. J. & Marquardt, F. Cavity optomechanics. Reviews of Modern Physics 86, 1391-1452, (2014) Wilson, D. J. et al. Measurement and control of a mechanical oscillator at its thermal decoherence rate. Nature (2014). Verhagen, E., Deleglise, S., Weis, S., Schliesser, A. & Kippenberg, T. J. Quantum-coherent coupling of a mechanical oscillator to an optical cavity mode. Nature 482, 63-67 (2012). Kippenberg, T. J., Holzwarth, R. & Diddams, S. A. Microresonator-based optical frequency combs. Science 332, 555-559, (2011). Weis, S. et al. Optomechanically induced transparency. Science 330, 1520-1523 (2010). Kippenberg, T. J. & Vahala, K. J. Cavity optomechanics: back-action at the mesoscale. Science 321, 1172-1176, (2008). Del'Haye, P. et al. Optical frequency comb generation from a monolithic microresonator. Nature (2007) Schliesser, A., DelHaye, P., Nooshi, N., Vahala, K. & Kippenberg, T. Radiation Pressure Cooling of a Micromechanical Oscillator Using Dynamical Backaction. Physical Review Letters 97, (2006). 