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Complications of diabetes

Related people (23)

Johan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways. Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards. Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.

Giovanni De Micheli

Expertise Design technologies for integrated systems on silicon, such as synthesis, hw/sw codesign and low-power design, as well as systems on heterogeneous platforms including electrical and biological components. Scientific Director of EcoCloud Center at EPFL Directing activities towards creating sustainable computation including AI.Designing energy-savvy data centers and edge devices. More information Please read http://si2.epfl.ch/~demichel/ Giovanni De Micheli is a research scientist in electronics and

Kristina Schoonjans

Expertise Bile acid signalingNutrient sensingIntermediary metabolismMetabolic disorders Teaching & PhD PhD Students Adrien Faure Past EPFL PhD Students Pan Xu, Ece Yildiz, Nadia Bresciani, Yu Sun, Francesca Pontanari, Alejandro Alonso Calleja Past EPFL PhD Students as codirector Mitsunori Nomura, Pan Xu, Katyayanee Neopane, Lucie Camille Chanvillard, Jakob Josef Langer, Bilge Sen Elçi Courses General Biology BIOENG-110 The purpose of the course is to provide a general overview of the biolo

Daniel Ortiz Trujillo

Teaching & PhD Courses Mass spectrometry, principles and applications CH-728 The goal is to provide students with a complete overview of the principles and key applications of modern mass spectrometry and meet the current practical demand of EPFL researchers to improve structural analsis of molecules. Numerous instrumental aspects of mass spectrometry are described.

Laure Menin

Expertise Mass spectrometryLC-MS / GC-MSBiochemistryProteomicsToxinologyDrug discovery Teaching & PhD Courses Mass spectrometry, principles and applications CH-728 The goal is to provide students with a complete overview of the principles and key applications of modern mass spectrometry and meet the current practical demand of EPFL researchers to improve structural analsis of molecules. Numerous instrumental aspects of mass spectrometry are described.

Solomzi Makohliso

Teaching & PhD Courses Development engineering ENV-470 This course teaches the fundamentals of technologies for development (Development Engineering) to design, pilot, and deploy appropriate, affordable and robust technologies to address sustainable development challenges and especially those related to extreme poverty in Low-income settings. Science, Technology & Vulnerability HUM-287 This course explores how science and technology can address extreme vulnerability caused by

Pierre Magistretti

Pierre J. Magistretti is an internationally-recognized neuroscientist who has made significant contributions in the field of brain energy metabolism. His group has discovered some of the cellular and molecular mechanisms that underlie the coupling between neuronal activity and energy consumption by the brain. This work has considerable ramifications for the understanding of the origin of the signals detected with the current functional brain imaging techniques used in neurological and psychiatric research (see for example Magistretti et al, Science, 283: 496 497, 1999). He is the author of over 100 articles published in peer-reviewed journals. He has given over 80 invited lectures at international meetings or at universities in Europe and North America, including the 2000 Talairach Lecture at the Functional Mapping of the Human Brain Conference. In November 2000 he has been a Mc Donnel Visiting Scholar at Washington University School of Medicine. Pierre J. Magistretti is the President-Elect (2002 2004) of the Federation of European Neuroscience Societies (FENS) which has a membership of over 15000 European neuroscientists. He has been first president of the Swiss Society for Neuroscience (1997-1999) and the first Chairman of the Department of Neurosciences of the University of Lausanne (1996 1998). Pierre J. Magistretti is Professor of Physiology (since 1988) at the University of Lausanne Medical School. He has been Vice-Dean of the University of Lausanne Medical School from 1996 to 2000. Pierre Magistretti, is Director of the Brain Mind Institute at EPFL and Director of the Center for Psychiatric Neuroscience of the University of Lausanne and CHUV. He is also Director of the NCCR SYNAPSY "the synaptic bases of mental diseases". POSITIONS AND HONORS MAIN POSITION HELD 1988-2004 Professor of Physiology, University of Lausanne Medical School 1996-2000 Vice-Dean for Preclinical Departments, University of Lausanne Medical School 2001-2004 Chairman, Department of Physiology, University of Lausanne Medical School 2004-present Professor and Director, Center for Psychiatric Neuroscience, Department of Psychiatry, University of Lausanne Medical School and Hospitals (UNIL-CHUV) (Joint appointment with EPFL) 2005-2008 Professor and Co-Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne (Joint appointment with UNIL-CHUV) 2007-present Chairman of the Scientific Advisory Board of Centre dImagerie Biomédicale (CIBM), an Imaging Consortium of the Universities, University Hospitals of Lausanne and Geneva and of Ecole Polytechnique Fédérale de Lausanne 2008-present Professor and Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne Joint appointment with UNIL-CHUV) 2010-present Director, National Center for Competence in Research (NCCR) The synaptic bases of mental diseases of the Swiss National Science Foundation 2010-present Secretary General, International Brain Research Organization (IBRO) MAIN HONORS AND AWARDS 1997 Recipient of the Theodore-Ott Prize of the Swiss Academy of Medical Sciences 2001 Elected Member of Academia Europaea 2001 Elected Member of the Swiss Academy of Medical Sciences, ad personam 2002 Recipient of the Emil Kraepelin Guest Professorship, Max Planck Institute für Psychiatry, Münich 2006 Elected Professor at Collège de France, Paris, International Chair 2007-2008 2009 Goethe Award for Psychoanalytic Scholarship, Canadian Psychological Association 2011 Camillo Golgi Medal Award, Golgi Fondation 2011 Elected Member of the American College of NeuroPsychopharmacology (ACNP)

Denis Gillet

Denis Gillet received the Diploma in Electrical Engineering from the Swiss Federal Institute of Technology in Lausanne (EPFL) in 1988, and the Ph.D. degree in Information Systems also from the EPFL in 1995. During 1992 he was appointed as Research Fellow at the Information Systems Laboratory of Stanford University in the United States. He is currently Maître d'enseignement et de recherche at the EPFL School of Engineering, where he leads the React research group. His current research interests include Technologies Enhanced Learning (TEL), Human Computer Interaction (HCI), Human Devices Interaction (HDI) and Optimal Coordination of Complex and Distributed Systems. Denis Gillet is affiliated at EPFL with the Center for Intelligent Systems and the Center for Digital Education.

Grégory François

Nikolaos Stergiopoulos

Education MTE, Managing the Technology Enterprise Program (2000), IMD, Lausanne Ph.D. in Biomedical Engineering & Engineering Mechanics (1990) Iowa State University, Ames, Iowa. MS in Biomedical Engineering (1987) Iowa State University, Ames, Iowa. Diploma in Mechanical Engineering (1985) National Technical University of Athens. Professional Activities 2002 - present: Professor and director of LHTC 2010 - present: Founder and director of Rheon Medical SA, Préverenges, Switzerland 2008 - present: Founder and director of Antlia S.A., PSE-C, EPFL campus, Switzerland 1998 - 2007: Founder and Scientific Director of EndoArt S.A., Lausanne, Switzerland 1996 - 2002: Assistant professor at the Biomedical Engineering Laboratory, Swiss Federal Institute of Technology, Lausanne, Switzerland. 1991 - 1996: Research Associate at Swiss Federal Institute of Technology - Lausanne 1990 - 1991: Lecturer, Iowa State University

Paul Joseph Dyson

Paul Dyson joined the Institute of Chemical Sciences and Engineering at the EPFL in 2002 where he heads the Laboratory of Organometallic and Medicinal Chemistry and between 2008 and 2016 chaired the Institute. He has won several prizes including the Werner Prize of the Swiss Chemical Society in 2004, the Award for Outstanding Achievements in Bioorganometallic Chemistry in 2010, the Centennial Luigi Sacconi Medal of the Italian Chemical Society in 2011, the Bioinorganic Chemistry Award of the Royal Society of Chemistry in 2015, the European Sustainable Chemistry Award of the European Chemical Society in 2018 and the Green Chemistry Award from the Royal Society of Chemistry in 2020. He is also a Clarivate Highly Cited Researcher and has an H-index >110 (web of science and google scholar). He was elected a Fellow of the Royal Society of Chemistry in 2010, a Fellow of the European Academy of Science in 2019 and a life-long fellow of the American Association for the Advancement of Science in 2020. Over the years he has held visiting professorships at the University of Bourgogne, University of Pierre et Marie Curie, University of Vienna, University of Rome Tor Vergara, Chimie Paristech and Shangai Jiao Tong University.Since 2016 he has been Member of the Council of the Division of Mathematics, Natural and Engineering Sciences at the Swiss National Science Foundation.Between 2016-2021 he has been Member of the Council of the Division of Mathematics, Natural and Engineering Sciences at the Swiss National Science Foundation. In 2021 he was appointed Dean of the Faculty of Basic Sciences.

Sandrine Gerber

Sandrine Gerber studied chemistry at the "Ecole Nationale Supérieure de Chimie de Paris" in France, where she obtained a diploma of chemical engineer in 1993. The same year she obtained a DEA (Master degree) of organic chemistry at the University Pierre et Marie Curie (Paris VI, France). From 1993 to 1996 she did a PhD in organic chemistry under the supervision of Prof. Jean-Pierre Genêt at the Ecole Nationale Supérieure de Chimie de Paris. In 1996, she moved to University of Lausanne for a post-doctoral stay under the supervision of Prof. Pierre Vogel. In 1998, she was appointed Maître-Assistante at the Institute of Organic Chemistry in the University of Lausanne. In 2003, she obtained the habilitation to direct research from the University Pierre et Marie Curie (Paris VI, France). The same year, she was appointed scientific adjunct at the EPFL and senior scientist (Maître d'Enseignement et de Recherche) in 2006. In December 2014, she was promoted to titular professor. Since September 2007, Sandrine Gerber is deputy to the director of the Institute of Chemical Sciences and Engineering (ISIC). She is also member of the Board of Directors of the Swiss Chemical Society. Since 2007, Sandrine Gerber is part-time lecturer at the university of Fribourg. She was awarded the Prize Eugene Schueller in 1997, the Prize Dufour for prospective organic chemistry in 2005 and the Werner Prize 2010. She also received a special mention in recognition of exceptional quality of pedagogic competencies in the teaching of basic sciences, given by the Direction of the School of Biology and Medicine from the University of Lausanne, in 2013. In October 2018, she will receive the Prize for Excellence in Teaching from the section of Chemistry and Chemical Engineering.

Lucia Baldi Unser

01/2021 - present Deputy to the Associate VP for Research / Deputy to the Associate VP for Centers & Platforms, EPFL06/2017 - 12/2020 Deputy to the Dean, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne ;01/2015 - 11/2017 Lecturer/Communication and outreach manager at the School of Life Sciences, EPFL04/1998 - 03/2015: Research and Teaching Associate/Lecturer, Laboratory of Cellular Biotechnology, School of Life Sciences; 01/1994 - 07/1997: Visiting Fellow, Laboratory of Immunoregulation, NIAID, NIH, Bethesda, Maryland, USA;1991 - 1994: Research Fellow, Laboratory of Pediatric Oncology, G. Gaslini Scientific Institute, Genova, Italy;1987 - 1990: Research Fellow, Clinical Immunology and Immunogenetics Dept., Nat. Inst. for Cancer Research, Genova, Italy.

David Hacker

Expertise Animal cell cultivationTransient transfectionStable cell line generationExpression vector designProtein purification Teaching & PhD Past EPFL PhD Students as codirector Agata Oberbek, Yashas Rajendra, Xiao Shen, Dominique Terry Monteil Jr, Sowmya Balasubramanian Courses Recombinant protein expression in animal cells for appli-cations in medicine and structural biology BIO-701 Cultivated animal cells are important hosts for the production of recombinant proteins for biochemical and

Adan Villamarin

Paolo Germano

FORMATION Mars 1990 : Engagement au Laboratoire d'électromécanique et de machines électriques (LEME), devenu entre temps le laboratoire d'actionneurs intégrés (LAI), comme assistant puis comme fonctionnaire scientifique. Janvier 1990 : Diplôme d'ingénieur EPF en microtechnique. Juillet 1985 : Maturité de type scientifique.

- - EXPERIENCES ET DOMAINES DE COMPETENCES
Modélisation et simulation de l'alimentation des moteurs de l'avion Solar Impulse sur la base des résultats de la modélisation par éléments finis (FEM) de la structure magnétique Développement du banc de mesure (mécanique et software) du moteur Solar Impulse (dès mars 2004);
Dans le cadre d'un Projet CTI en collaboration avec l'entreprise Medtronic (Projet ColoStim), développement d'un appareil de traitement de la constipation consistant en des électrodes implantées le long du colon et alimentées par induction, à haute fréquence, à l'aide d'une bobine primaire placée autour du thorax du patient (janvier 2006 - mars 2007);
Développement du modèle équivalent d'une montre à glace tactile et analyse de l'effet des décharges électrostatiques sur cette montre. Projet CTI en collaboration avec l'entreprise ETA-Swatch Group (avril 2003 à octobre 2004);
Développement d'un système de transfert d'énergie pour navettes automotrices de machines d'assemblage. Projet CTI en collaboration avec l'entreprise Montech AG (octobre 2001 à octobre 2002);
Développement d'une installation de transfert d'énergie pour des wagonnets de transport de rouleaux pour l'industrie du papier avec l'entreprise Valmet AG (Groupe Metso Paper) (2001);
Développement d'un banc de mesure pour actionneurs linéaires dans le cadre d'un mandat avec l'entreprise Sonceboz SA (mars 1998 - juillet 2000);
Développement d'une installation de transfert d'énergie pour un convoyeur d'outils dans le cadre d'un mandat avec l'entreprise MCM SpA (Italie) (juillet 1998 avril 1999 et déc. 1999 avril 2000);
Développement d'un banc de test pour vibreur électromécanique dans le cadre d'un mandat avec l'entreprise ASULAB SA à Marin (octobre décembre 1999);
Développement et responsabilité d'une installation de démonstration d'un Système de transport automatique à transmission d'énergie par induction - Projet Serpentine 2 PSEL (déc. 1996 juin 1999);
Développement d'un banc de mesure et d'analyse pour moteurs à courant continu dans le cadre d'un projet d'impulsion RAVEL (sept. 1995 - mars 1997);
Développement d'un convertisseur de fréquence à résonance de 2,4 kW pour l'alimentation d'un transformateur sans fer dans le cadre du transfert d'énergie sans contacts Projet Serpentine PSEL (février 94 déc. 1995);
Développement d'un banc de mesure pour moteurs pas à pas dans le cadre d'un mandat avec l'entreprise Sonceboz SA (mars 1992 nov. 1995);
Développement d'un convertisseur direct de fréquence AC/AC de basse puissance dans le cadre du projet du cur artificiel Suisse (mars 1990 - mars 1992);
Suivi d'une vingtaine de projets de semestre et de master EPFL;
Divers projets de moindre envergure (alimentations, démonstrateurs, acquisitions de données, micro-informatique, circuits imprimés).

PUBLICATIONS DOMAINE DU TRANSFERT D'ENERGIE PAR INDUCTION M. Jufer, L. Cardoletti, B. Arnet, P. Germano, Ch. Koechli, N. Macabray, M. Perrottet, "Dispositif de transmission d'énergie électrique à un véhicule, sans contact, par induction - Projet PSEL N° 16 - Magnéto-glisseur", Rapport de synthèse 1995, EPFL-DE-LEME, Lausanne - Suisse, 18 octobre 1995; M. Jufer, L. Cardoletti, P. Germano, B. Arnet, M. Perrottet, N. Macabrey, "Induction Contactless Energy Transmission System for an Electric Vehicle", ICEM96, International Conference on Electrical Machines, Vigo, Sept. 10-12, 1996, Vol II, pp. 343-347; P. Germano, M. Jufer, "Contactless power transmission: Frequency tuning by a maximum power tracking method", EPE '97, 7th European Conference on power electronics and applications, Trondheim, Sept. 8-10, 1997, Vol IV, pp. 693-697; M. Jufer, L. Cardoletti, P. Germano, B. Arnet, M. Perrottet, Swiss Federal Institute of Techno-logy, DE-LEME, 1015 Lausanne, Switzer-land, "Inductively powered automatic vehicles - Ser-pen-tine", EVS-15 '98, 15th International Electric Vehicle Symposium and Exhibition, Brussel, Belgium, Sept. 29 - Oct. 3, 1998, pp. 403-404; P. Germano, Nicolas Macabrey, M. Jufer, Swiss Federal Institute of Technology, DE-LEME, 1015 Lausanne, Switzerland, "Contactless Power Transmission: Linear Positioning of the Moving Element", EPE '99, 8th European Conference on Power Electronics and Applications, Lausanne, 7-9 September, 1999, Art Nb 685; P. Germano, M. Jufer, L. Cardoletti, B. Arnet, Ch. Koechli, N. Macabray, M. Perrottet, "Système de transport automatique à transmission d'énergie par induction. - Projet PSEL N° 115", Rapport final 1999, EPFL-DE-LEME, Lausanne - Suisse, 31 août 1999; P. Germano, I. Stefanini, W. Montella, L. Cardoletti, Y. Perriard, "Système de transfert d'énergie pour navette de machines d'assemblage Projet CTI n° 5780.1 KTS", Rapport final, EPF Lausanne-LAI, Suisse, mars 2004; I. Stefanini, P. Germano, L. Cardoletti, W. Montella, Y. Perriard, "Inductive Charge System for Assembly Plant Shuttles", CD-ROM, EPE 2003, Toulouse, (France), 2-4 Septembre 2003; P. Germano, I. Stefanini, Y. Perrirad, "Stimulation colique pour le traitement des troubles de la motilité Projet ColoStim Projet CTI n° 7362.2 LSPP-LS", Rapport final, EPF Lausanne-LAI, Suisse, mai 2007. DOMAINES DES BANCS DE MESURE - MESURES P. Germano, "Système automatique de mesure", Rapport technique vol. I & II, EPF-Lausanne, 1995; P. Germano, Ch. Kuert, "Banc de mesures automatisé pour entraînements électriques", Présentation et mode d'emploi, EPF-Lausanne, 1997; P. Germano, Ch. Kuert, M. Jufer, Swiss Federal Institute of Technology, DE-LEME, 1015 Lausanne, Switzerland, "Automated test bench for electric drives: Modular layout of soft- and hardware", EPE '99, 8th European Conference on Power Electronics and Applications, Lausanne, 7-9 September, 1999, Art Nb 683; Y. Perriard, P. Germano, I. Verettaz, "Banc de test pour vibreur électromécanique", Rapport technique, EPF-Lausanne, janvier 2000; P. Germano, Ch. Kuert, M. Jufer, Swiss Federal Institute of Technology, DE-LEME, 1015 Lausanne, Switzerland, "DSP controlled automated Test Bench for linear Actuators Design and Choices", EPE 2001, 9th European Conference on Power Electronics and Applications, Graz, 27-29 August, 2001, Art Nb 709; P. Germano, M. Crivii, D. Demarco, Y. Perriard, Swiss Federal Instutute of Technology, LAI, 1015 Lausanne, Switzerland & L. Paratte, R. Marquis, Service Unit RD, ETA SA (Swatch Group), 2540 Granges, Switzerland, "Analysis and Modeling of Electrostatic Discharge in a Tactile Glass Featured Watch", IAS 2004, 39th Annual Meeting, Seattle, WA, USA, October 3-7, 2004; P. Germano, M. Crivii, D. Demarco, Y. Perriard, Swiss Federal Instutute of Technology, LAI, 1015 Lausanne, Switzerland & L. Paratte, R. Marquis, Service Unit RD, ETA SA (Swatch Group), 2540 Granges, Switzerland, "Analysis and Modeling of Electrostatic Discharge in a Tactile Glass Featured Watch", IEEE Transaction on Industry Applications, Volume 43, Issue 4, July-aug. 2007, Page(s): 1091-1098;

Christian Köchli

Teaching & PhD PhD Students Maël Dagon Past EPFL PhD Students as codirector Sebastiano Merzaghi, Chafic Abu Antoun, Florian Louis Copt, Sofia Lydia Ntella Courses Actuators and Electromagnetic systems I MICRO-313 The course covers the main methods for the analysis of electromechanical systems. A study of magnetic physical quantities is followed by the conversion of electrical energy into mechanical energy. The permanent magnet is studied macroscopically. The dynamic aspect of the system is

Yves Perriard

Yves Perriard was born in Lausanne in 1965. He received the M. Sc. in Microengineering from the Swiss Federal Institute of Technology - Lausanne (EPFL) in 1989 and the Ph D. degree in 1992. Co-founder of Micro-Beam SA, he was CEO of this company involved in high precision electric drive. Senior lecturer from 1998 and professor since 2003, he is currently director of Laboratory of Integrated Actuators. His research interests are in the field of new actuator design and associated electronic devices. In 2009, he is appointed Vice-Director of the Microengineering Institute in Neuchâtel until 2011. In 2013 the Federal Council has named him the the CTI commission in Bern. In 2014 he is appointed guest professor at Zhejiang University in China. In 2017, the lab is granted by the Werner Siemens Foundation of an amount of 12 millions CHF in order to set up a new Center for Artificial Muscules. Since 2018, he is Expert with Innosuisse, the new Swiss Innovation Agency. http://scholar.google.com/citations?hl=fr&user=V2onuO8AAAAJ https://actu.epfl.ch/news/a-12-million-franc-donation-to-create-a-center-for/

Yoan René Cyrille Civet

Teaching & PhD PhD Students Simon Holzer Past EPFL PhD Students as codirector Dan Shi, Jasha Poliakine, Jonathan Chavanne, Quentin Philippe Mario De Menech Courses Electrotechnics I MICRO-100 The course covers the basics of electrical circuits composed of linear components, in direct current (DC) operation. A series of transforming methods are studied. At the end of the semester, alternate current (AC) systems are treated (complex numbers). Many examples and demos illustrate the course.

Rolf Gruetter

Awards: 1999 Young Investigator Award Plenary Lectureship , International Society for Neurochemistry 2011 Fellow , ESMRMB 2011 Teaching Award , Section Sciences de la Vie, EPFL

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