Harald Hirlingsince 2018:Adjoint du Doyen SV, Responsable Finance SVsince 2008: Adjoint du Doyen SV 2002-2010: Adjoint scientifique, SV-LNC, EPFL 2006-2008: Adjoint de Section SSV 2003-2004: coordinator (directeur) of the doctoral program in Neuroscience, EPFL Doctoral School 1994-2001: University of Lausanne Stanford University Institut Curie, Paris Education: ISREC, Epalinges (Switzerland). University of Konstanz (Germany)
Pierre MagistrettiPierre J. Magistretti is an internationally-recognized neuroscientist who has made significant contributions in the field of brain energy metabolism. His group has discovered some of the cellular and molecular mechanisms that underlie the coupling between neuronal activity and energy consumption by the brain.
This work has considerable ramifications for the understanding of the origin of the signals detected with the current functional brain imaging techniques used in neurological and psychiatric research (see for example Magistretti et al, Science, 283: 496 497, 1999). He is the author of over 100 articles published in peer-reviewed journals.
He has given over 80 invited lectures at international meetings or at universities in Europe and North America, including the 2000 Talairach Lecture at the Functional Mapping of the Human Brain Conference. In November 2000 he has been a Mc Donnel Visiting Scholar at Washington University School of Medicine.
Pierre J. Magistretti is the President-Elect (2002 2004) of the Federation of European Neuroscience Societies (FENS) which has a membership of over 15000 European neuroscientists. He has been first president of the Swiss Society for Neuroscience (1997-1999) and the first Chairman of the Department of Neurosciences of the University of Lausanne (1996 1998).
Pierre J. Magistretti is Professor of Physiology (since 1988) at the University of Lausanne Medical School. He has been Vice-Dean of the University of Lausanne Medical School from 1996 to 2000. Pierre Magistretti, is Director of the Brain Mind Institute at EPFL and Director of the Center for Psychiatric Neuroscience of the University of Lausanne and CHUV. He is also Director of the NCCR SYNAPSY "the synaptic bases of mental diseases".
POSITIONS AND HONORS
MAIN POSITION HELD
1988-2004 Professor of Physiology, University of Lausanne Medical School
1996-2000 Vice-Dean for Preclinical Departments, University of Lausanne Medical School
2001-2004 Chairman, Department of Physiology, University of Lausanne Medical School
2004-present Professor and Director, Center for Psychiatric Neuroscience, Department of Psychiatry, University of Lausanne Medical School and Hospitals (UNIL-CHUV) (Joint appointment with EPFL)
2005-2008 Professor and Co-Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne (Joint appointment with UNIL-CHUV)
2007-present Chairman of the Scientific Advisory Board of Centre dImagerie Biomédicale (CIBM), an Imaging Consortium of the Universities, University Hospitals of Lausanne and Geneva and of Ecole Polytechnique Fédérale de Lausanne
2008-present Professor and Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne Joint appointment with UNIL-CHUV)
2010-present Director, National Center for Competence in Research (NCCR)
The synaptic bases of mental diseases of the Swiss National Science Foundation
2010-present Secretary General, International Brain Research Organization (IBRO)
MAIN HONORS AND AWARDS
1997 Recipient of the Theodore-Ott Prize of the Swiss Academy of Medical Sciences
2001 Elected Member of Academia Europaea
2001 Elected Member of the Swiss Academy of Medical Sciences, ad personam
2002 Recipient of the Emil Kraepelin Guest Professorship, Max Planck Institute für Psychiatry, Münich
2006 Elected Professor at Collège de France, Paris, International Chair 2007-2008
2009 Goethe Award for Psychoanalytic Scholarship, Canadian Psychological Association
2011 Camillo Golgi Medal Award, Golgi Fondation
2011 Elected Member of the American College of NeuroPsychopharmacology (ACNP)
Hubert GiraultEducation: 1979 - Engineering diploma from Grenoble Institute of Technology. FRANCE. 1982 - PhD- Department of Chemistry, University of Southampton. Thesis entitled : Interfacial studies using drop image processing techniques. Positions : 1982 - 1984 SERC Research Fellow. University of Southampton. 1984 - 1985 CNRS Research Fellow. University of Southampton. 1985 - 1992 Lecturer in Physical Chemistry, University of Edinburgh. 1992 - Professor of Physical Chemistry, Ecole Polytechnique Fédérale de Lausanne. 2011 - 2014 Dean of Bachelor and Master studies Hubert Girault is the author of 2 textbooks, the co-author of about 600 scientific publications with more than 20'000 citations and the co-inventor of more than 15 patents. During his academic career, he has supervised 70 PhD students. 30 alumni of his laboratory are now Professors. Honours: Faraday medal 2006, Royal Society of Chemistry, Fellow of the International Society of Electrochemistry 2007, Reilley Award 2015. Fellow of the Electrochemical Society (USA), Shikata International medal, Polarography Society of Japan. Associate editor of Chemical Science
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
Sophie LufkinFORMATION
2010 - Thèse de doctorat au sein de l'EDAR (Ecole doctorale Architecture, Ville, Histoire) sur la densification des friches ferroviaires, co-dirigée par les Prof. Inès Lamunière et Vincent Kaufmann
2005 - "Master of Art" en architecture, sous la direction des Prof. Patrick BERGER et Inès LAMUNIERE
2003 - Année d'échange à l'ETHZ
1999 - Entrée à l'EPFL, section architecture
1998 - Maturité type B, Collège Claparède, Genève
EXPERIENCE PROFESSIONNELLE
2010 - Architecte, Cheffe de projet chez LAR - Fernando Romero, México
2006 - Assistante de recherche à lEPFL au Laboratoire darchitecture et mobilité urbaine (LAMU), projet de recherche PNR54 "Densification des friches ferroviaires"
2005 - Architecte chez Devanthéry & Lamunière, Genève
2004 - Stage darchitecture, Eric Maria, Genève
2003 - Stage darchitecture, Sumi & Burkhalter, Zurich
2001 - Stage darchitecture, Devanthéry & Lamunière, Genève
RECOMPENSES ET BOURSES
2001 - Prix SIA Vaudoise pour le projet "Fondation Ella Maillart à Chandolin"
2005 - Prix de l'Association des diplômes A3-EPFL
2008 - Bourse Erna Hamburger
LANGUES
Français (maternelle), allemand et anglais (courantes), portugais (notions)
Stephan BrunnerTeaching & PhD PhD Students Hugo Jean Elie Chkroun, Nicole Vadot, Oraz Anuaruly, Haomin Sun, Isabel Muzio, Fabien Nicolas Jeanquartier Past EPFL PhD Students Ajay Chandrarajan Jayalekshmi, Arnas Volcokas Past EPFL PhD Students as codirector Xavier Lapillonne, Thibaut Vernay, Julien Stanislas Pierre Dominski, Gabriele Merlo, Emmanuel Lanti, Noé Ohana, Moahan Murugappan Courses Plasma instabilities PHYS-736 To complete the theoretical knowledge acquired before the graduate studies.
Olexiy KochubeyTeaching & PhD PhD Students Nishant Jana Past EPFL PhD Students as codirector Aiste Baleisyte, Denys Osypenko Courses Neural circuits of motivated behaviors BIO-499 Motivated behaviors fulfil the basic physiological needs of animals and enable their safety. In this course, you will learn about the neuronal circuits that sense and regulate internal states, detect dangers in the environment, and organize appropriate behavioral responses.
Bernard SchneiderTeaching & PhD PhD Students Yesica Gloria, Christian Schellhaas Past EPFL PhD Students Vanessa Laversenne, Sameer Mohammad Khaleel Nazeeruddin, Emma Charlotta Källstig Past EPFL PhD Students as codirector Philippe Guillaume Coune, Emilda Pino, Elisabeth Anne Dirren, Aurélien Lathuilière, Wojciech Janusz Bobela, Lu Zheng, Cylia Cloé Rochat Courses Methods: from disease models to therapy BIOENG-518 This course will describe methods underlying translational approaches from disease modeling an
Xile HuXile Hu was born in 1978 in Putian, southeastern China. He entered the Peking University in Beijing in 1996. Besides learning too little chemistry, his biggest regret in the college was not able to correct his southern accent in Mandarin. After graduated from PKU, he went to the United States and began his doctoral studies at the University of California, San Diego. In December 2004, he finished with a Ph.D. in chemistry and some fond memories of the beautiful city of San Diego. He then moved to the Los Angeles area and become a postdoctoral scholar at the California Institute of Technology. There he enjoyed numerous stimulating scientific (and other) discussions with friends and colleagues. He also made plenty of friends outside the campus and was a frequent in many local Chinese restaurants. In 2007, after two pleasant visits to Switzerland, he decided to move across the continent one more time and join the faculty of the École Polytechnique Fédérale de Lausanne (EPFL). He now directs the Laboratory of Inorganic Synthesis and Catalysis and is interested in developing chemistry for synthesis, energy and sustainability.
Dominique BonvinDominique Bonvin is Professor and Director of the Automatic Control Laboratory of EPFL. He received his Diploma in Chemical Engineering from ETH Zürich, and his Ph.D. degree from the University of California, Santa Barbara. He worked in the field of process control for the Sandoz Corporation in Basel and with the Systems Engineering Group of ETH Zürich. He joined the EPFL in 1989, where his current research interests include modeling, control and optimization of dynamic systems. He served as Director of the Automatic Control Laboratory for the periods 1993-97, 2003-2007 and again since 2012, Head of the Mechanical Engineering Department in 1995-97 and Dean of Bachelor and Master Studies at EPFL for the period 2004-2011.
Wulfram GerstnerWulfram Gerstner is Director of the Laboratory of Computational Neuroscience LCN at the EPFL. His research in computational neuroscience concentrates on models of spiking neurons and spike-timing dependent plasticity, on the problem of neuronal coding in single neurons and populations, as well as on the link between biologically plausible learning rules and behavioral manifestations of learning. He teaches courses for Physicists, Computer Scientists, Mathematicians, and Life Scientists at the EPFL. After studies of Physics in Tübingen and at the Ludwig-Maximilians-University Munich (Master 1989), Wulfram Gerstner spent a year as a visiting researcher in Berkeley. He received his PhD in theoretical physics from the Technical University Munich in 1993 with a thesis on associative memory and dynamics in networks of spiking neurons. After short postdoctoral stays at Brandeis University and the Technical University of Munich, he joined the EPFL in 1996 as assistant professor. Promoted to Associate Professor with tenure in February 2001, he is since August 2006 a full professor with double appointment in the School of Computer and Communication Sciences and the School of Life Sciences. Wulfram Gerstner has been invited speaker at numerous international conferences and workshops. He has served on the editorial board of the Journal of Neuroscience, Network: Computation in Neural Systems', Journal of Computational Neuroscience', and `Science'.
Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Stewart ColeProfessor Stewart Cole is an international authority in bacterial molecular-genetics and genomics. He has made outstanding contributions in several fields including: bacterial anaerobic electron transport; genome analysis of retroviruses and papillomaviruses; antibiotic resistance mechanisms; and the molecular microbiology of toxigenic clostridia. His studies on isoniazid and multidrug resistance in Mycobacterium tuberculosis, together with his pioneering work on the pathogenicity, evolution and genomics of the tubercle and leprosy bacilli, have made him an undisputed leader in the field of mycobacterial research. The findings of his research are of direct relevance to public health and disease-control in both the developing world and the industrialised nations. He has published over 250 scientific papers and review articles, and holds many patents.
Mohammad Khaja NazeeruddinDr. Md. K. Nazeeruddin received M.Sc. and Ph. D. in inorganic chemistry from Osmania University, Hyderabad, India. He joined as a Lecturer in Deccan College of Engineering and Technology, Osmania University in 1986, and subsequently, moved to Central Salt and Marine Chemicals Research Institute, Bhavnagar, as a Research Associate. He was awarded the Government of Indias fellowship in 1987 for study abroad. In 2014, EPFL awarded him the title of Professor. His current research at EPFL focuses on Dye Sensitized Solar Cells, Perovskite Solar Cells, CO2 reduction, Hydrogen production, and Light-emitting diodes. He has published more than 509 peer-reviewed papers, ten book chapters, and he is inventor/co-inventor of over 50 patents. The high impact of his work has been recognized by invitations to speak at over 130 international conferences, and has been nominated to the OLLA International Scientific Advisory Board. He appeared in the ISI listing of most cited chemists, and has more than 49'000 citations with an h-index of 105. He is teaching "Functional Materials" course at EPFL, and Korea University; directing, and managing several industrial, national, and European Union projects. He was awarded EPFL Excellence prize in 1998 and 2006, Brazilian FAPESP Fellowship in 1999, Japanese Government Science & Technology Agency Fellowship, in 1998, Government of India National Fellowship in 1987-1988. Recently he has been appointed as World Class University (WCU) professor by the Korea University, Jochiwon, Korea (http://dses.korea.ac.kr/eng/sub01_06_2.htm), Adjunct Professor by the King Abdulaziz University, Jeddah, Saudi Arabia and Eminent Professor in Brunei. Gabriela Tejada GuerreroGabriela has extensive expertise in international cooperation in education, research and innovation. She joined EPFL as scientist at the Cooperation and Development Center (CODEV) where she led the EPFL Leading House Program (2014-2017) of the Swiss government, which upheld Swiss bilateral research cooperation with Brazil, India, Vietnam and Latin America. Her research focused on scientific diasporas and skilled migration with diverse international collaborations under her leadership. She worked at the University of Zurich, and the UNDP in Moldova and Geneva, and taught at the Monterrey Institute of Technology (ITESM). She was visiting researcher at the CES at Harvard University and the CIS at ETH Zurich. Gabriela obtained a BA in International Relations from the UIA (Ibero) in Mexico, and a PhD in Political Sciences from the UAB in Barcelona. She obtained a CAS IPA - International Policy and Advocacy of the D-MTEC, ETH Zurich (2019). Since 2020 Gabriela is Vice-President of the Swiss Commission for UNESCO (member since 2016), where she promotes science-society linkages and advocates for an inclusive development and dialogue through education, science and culture.Since May 2019, Gabriela is Academic Deputy at the Direction of the College of Humanities (CDH). She serves the Scholars at Risk program (SAR) at EPFL in an advisory capacity.
Martine LapriseTeaching & PhD Courses Vers des villes bioclimatiques ? AR-688
Giovanni De MicheliExpertise
Design technologies for integrated systems on silicon, such as synthesis, hw/sw codesign and low-power design, as well as systems on heterogeneous platforms including electrical and biological components.
Scientific Director of EcoCloud Center at EPFL
Directing activities towards creating sustainable computation including AI.Designing energy-savvy data centers and edge devices.
More information
Please read http://si2.epfl.ch/~demichel/
Giovanni De Micheli is a research scientist in electronics and Olivier SauterTeaching & PhD PhD Students Cassandre Ekta Contré, Antonia Frank, Peizheng Zhang, Jean-Pierre Thomas Svantner, Cristina Venturini, Cosmas Quirin Lorenz Heiss, Daniel Perales Rios, Viacheslav Bochkarev, Jan Jakub Frybes, Paul Véronique Guillaume Devianne Past EPFL PhD Students Clemente Angioni, Petri Nikkola, Alberto Bottino, Andrei Martynov, Emiliano Fable, Costanza Zucca, Federico Felici, Dávid Wágner, Doohyun Kim, Anna Teplukhina, Mengdi Kong, Francesco Carpanese, Simon Van Mulders, Stefano Marchioni, F
