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Related publications (28)

The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation

Genes implicated in translation control have been associated with autism spectrum disorders (ASDs). However, some important genetic causes of autism, including the 16p11.2 microdeletion, bear no obvious connection to translation. Here, we use proteomics, g ...

Amer Assoc Advancement Science2024

Opportunities, Challenges, and Pitfalls in Making, Characterizing, and Understanding Polymer Brushes

Harm-Anton Klok

Polymer brushes have been theoretically described, their behavior under diverse conditions has been modeled, and their preparation via surface-initiated polymerizations (SIPs) has been progressively refined. However, despite three decades of research endea ...

American Chemical Society2023

Transformer Models for Vision

Jean-Baptiste Francis Marie Juliette Cordonnier

The recent developments of deep learning cover a wide variety of tasks such as image classification, text translation, playing go, and folding proteins. All these successful methods depend on a gradient-based learning algorithm to train a model on massive ...

EPFL2023

A Rapid Translational Immune Response Program in CD8 Memory T Lymphocytes

Linlin Cao

The activation of memory T cells is a very rapid and concerted cellular response that requires coordination between cellular processes in different compartments and on different time scales. In this study, we use ribosome profiling and deep RNA sequencing ...

American Association of Immunologists ; Oxford University Press2022

Biochemistry of Aminoacyl tRNA Synthetase and tRNAs and Their Engineering for Cell-Free and Synthetic Cell Applications

Sebastian Maerkl, Ragunathan Bava Ganesh

Cell-free biology is increasingly utilized for engineering biological systems, incorporating novel functionality, and circumventing many of the complications associated with cells. The central dogma describes the information flow in biology consisting of t ...

FRONTIERS MEDIA SA2022

On the ‘cultural transfer’ of modern architecture northwards - Akzeptiere: Das Buch und seine Geschichte

Chiara Monterumisi

"Akzeptiere: Das Buch und seine Geschichte" is the latest in-depth contribution by Atli Magnus Seelow, one of several by him on the 1930 Stockholm exhibition and the book accepetera, the 200-page text often referred to as ‘the manifesto of Swedish function ...

2021

Discourse Phenomena in Machine Translation

Lesly Sadiht Miculicich Werlen

Machine Translation (MT) has made considerable progress in the past two decades, particularly after the introduction of neural network models (NMT). During this time, the research community has mostly focused on modeling and evaluating MT systems at the se ...

EPFL2021

Towards an artificial cell: Development of a system which self-regenerates the protein components of the PURE system in microfluidic reactors

Barbora Lavickova

Thanks to recent advancements in synthetic biology, the dream of creating a synthetic cell has become feasible. However, due to its inherent complexity, one of the fundamental functions of all living systems, i.e., self-replication, remains to be introduce ...

EPFL2021

Organic semiconductors for light-mediated neuromodulation

Diego Ghezzi, Danashi Imani Medagoda

There is growing interest in organic semiconductor devices for light-mediated neuromodulation, such as for retinal stimulation. Here, the key working principles of these devices are discussed, as well as promising applications and outstanding challenges fo ...

SPRINGERNATURE2021

Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2 alpha HRI kinase

Eva Ramos Fernandez

Wnt signaling plays a key role in neurodevelopment and neuronal maturation. Specifically, Wnt5a stimulates postsynaptic assemblies, increases glutamatergic neurotransmission and, through calcium signaling, generates nitric oxide (NO). Trying to unveil the ...

Nature Research2021

Sommerfeld Integrals and Their Relation to the Development of Planar Microwave Devices

Juan Ramon Mosig, Krzysztof Michalski

This paper deals with the mathematical expressions called Sommerfeld integrals. Introduced by A. Sommerfeld in 1909, they are mathematically equivalent to inverse Hankel transforms. The original historical goal of these integrals was to provide an accurate ...

Ieee-Inst Electrical Electronics Engineers Inc2021

Two degree of freedom oscillator system

Simon Nessim Henein, Mohammad Hussein Kahrobaiyan, Billy Nussbaumer, Arnaud André Emmanuel Maurel

Oscillator system (1) comprising:- a substantially planar frame (3);- a first sub-oscillator (5), a second sub-oscillator (7), a third sub-oscillator (9), and a fourth sub-oscillator (11), each sub-oscillator (5, 7, 9, 11) comprising a substantially rigid ...

2020

Innovation, industry and firm age: are there new knowledge production functions?

Gabriele Pellegrino

In this paper we investigate how the knowledge production function is at work in different industrial sectors comparing mature and young companies in Italy. We estimate a two-step model using community innovation survey data. We provide evidence that young ...

SPRINGER HEIDELBERG2020

On the Limitations of Cross-lingual Encoders as Exposed by Reference-Free Machine Translation Evaluation

Robert West, Maxime Jean Julien Peyrard, Yang Gao

Evaluation of cross-lingual encoders is usually performed either via zero-shot cross-lingual transfer in supervised downstream tasks or via unsupervised cross-lingual textual similarity. In this paper, we concern ourselves with reference-free machine trans ...

ASSOC COMPUTATIONAL LINGUISTICS-ACL2020

Lieu hologrammatique, un concept et une méthodologie complexe de mesure de l'organisation spatiale des réalités sociales

Thibault Pierre Louis Romany

The urban is a complex phenomenon whose exploration remains a important scientific challenge. Choosing complex thought in order to renew our capacities for understanding and action on and with the urban is not trivial. The complex thought developed by Edga ...

EPFL2020

Analysis and Remediation of Handwriting difficulties

Thibault Lucien Christian Asselborn

Even with correct training, up to 25% of children never master handwriting like their peers. While research shows a correlation between handwriting difficulties and school failure, these difficulties can also impact children in their self esteem and behavi ...

EPFL2020

High-throughput microfluidic platforms for characterizing and engineering cell-free gene regulatory circuits

Zoe Newell Swank

Cell-free systems have emerged as a versatile platform for constructing complex biological systems from the bottom-up. In particular, they enable the rapid engineering and characterization of gene regulatory networks, a critical cellular subsystem that all ...

EPFL2020

Wearable and Self-Aware Machine Learning System for Online Cognitive Workload Monitoring and Drone Control

Fabio Isidoro Tiberio Dell'Agnola

The use of robots in search and rescue is gaining particular interest, but singular skills are required to ensure efficient deployments in real missions. To face this problem, there is a need to develop more intuitive control interfaces. Moreover, to ensur ...

EPFL2020

Distribution of the ribosome associated endonuclease Rae1 and the potential role of conserved amino acids in codon recognition

Jérémie Piton

We recently identified a novel ribonuclease in Bacillus subtilis called Rae1 that cleaves mRNAs in a translation-dependent manner. Rae1 is a member of the NYN/PIN family of ribonucleases and is highly conserved in the Firmicutes, the Cyanobacteria and the ...

TAYLOR & FRANCIS INC2018

Word Sense Consistency in Statistical and Neural Machine Translation

Xiao Pu

Different senses of source words must often be rendered by different words in the target language when performing machine translation (MT). Selecting the correct translation of polysemous words can be done based on the contexts of use. However, state-of-th ...

EPFL2018