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Concept

Natural experiment

Related publications (32)

Comparing spatio-temporal networks of intermittent avalanche events: Experiment, model, and empirical data

Anjali Bagunu Tarun

Relaxational processes in many complex systems often occur in the form of avalanches resulting from internal cascades from across the system scale. Here, we probe the space, time, and magnitude signatures of avalanching behavior using a network of temporal ...

2020

Catalytic Enantioselective Transformations with Chiral Cyclopentadienyl Ruthenium(II) Complexes

Sung Hwan Park

The chemistry of cyclopentadienyl ruthenium(II) complexes plays an important role in ruthenium catalysis because of its high potential for various transformations. However, asymmetric catalysis with chiral cyclopentadienyl ruthenium(II) complexes is still ...

EPFL2020

Advanced Functional Decomposition Using Majority and Its Applications

Giovanni De Micheli, Mathias Soeken

Typical operators for the decomposition of Boolean functions in state-of-the-art algorithms are AND, exclusive-OR (XOR), and the 2-to-1 multiplexer (MUX). We propose a logic decomposition algorithm that uses the majority-of-three (MAJ) operation. Such a de ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2020

A simple, versatile and robust centrifugation-based filtration protocol for the isolation and quantification of alpha-synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in alpha-synuclein research

Hilal Lashuel, Anass Chiki, Muhammed Muazzam Kamil Syed, Sonia Donzelli

Increasing evidence suggests that the process of alpha-synuclein (alpha-syn) aggregation from monomers into amyloid fibrils and Lewy bodies, via oligomeric intermediates plays an essential role in the pathogenesis of different synucleinopathies, including ...

Wiley-Blackwell2020

Catechol Containing Polyelectrolyte Complex Nanoparticles as Local Drug Delivery System for Bortezomib at Bone Substitute Materials

Martin Guillermo Mueller, Jeremy Pak Hei Wong

The proteasome inhibitor bortezomib (BZM) is one of the most potent anti-cancer drugs in the therapy of multiple myeloma. In this study, an adhesive drug delivery system (DDS) for BZM was developed. Therefore, we extended the present DDS concept of polyele ...

2020

Joint Graph-based Depth Refinement and Normal Estimation

Pascal Frossard, Mireille El Gheche, Mattia Rossi

Depth estimation is an essential component in understanding the 3D geometry of a scene, with numerous applications in urban and indoor settings. These scenes are characterized by a prevalence of human made structures, which in most of the cases, are either ...

2020

The virtuous cycle of human genetics and mouse models in drug discovery

Johan Auwerx

Ongoing studies in many species seek to understand the origins, architecture and consequences of phenotypic variation under normal and dysfunctional conditions, with the aim of identifying targets for intervention that can prevent, stabilize or reverse dis ...

NATURE PUBLISHING GROUP2019

MMKG: Multi-modal Knowledge Graphs

Alberto Garcia Duran

We present Mmkg, a collection of three knowledge graphs that contain both numerical features and (links to) images for all entities as well as entity alignments between pairs of KGs. Therefore, multi-relational link prediction and entity matching communiti ...

SPRINGER INTERNATIONAL PUBLISHING AG2019

A Molecular Dual Pump

Cristian Pezzato

Artificial molecular machines (AMMs) built from mechanically interlocked molecules (MIMs) can use energy ratchets to control the unidirectional motion of their component parts. These energy ratchets are operated by the alteration of kinetic barriers and th ...

AMER CHEMICAL SOC2019

Pedestrian Image Generation for Self-driving Cars

Alexandre Massoud Alahi, Saeed Saadatnejad

Pedestrian image generation in the desired pose can be used in a wide range of applications e.g., person re-identification and tracking which are among the fundamental challenges in self-driving cars. This is a hard task because it should be invariant to a ...

2019

Learning By Collaborative Teaching : An Engaging Multi-Party CoWriter Activity

Pierre Dillenbourg, Wafa Monia Benkaouar Johal, Laila Abdelsalam El-Hamamsy, Thibault Lucien Christian Asselborn, Jauwairia Nasir

This paper presents the design of a novel and engaging collaborative learning activity for handwriting where a group of participants simultaneously tutor a Nao robot. This activity was intended to take advantage of both collaborative learning and the learn ...

2019

SBFT: a Scalable and Decentralized Trust Infrastructure

Dragos-Adrian Seredinschi

SBFT is a state of the art Byzantine fault tolerant state machine replication system that addresses the challenges of scalability, decentralization and global geo-replication. SBFT is optimized for decentralization and is experimentally evaluated on a depl ...

IEEE COMPUTER SOC2019