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Concept

Biological target

Related lectures (32)

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Proteome Mapping & Electrophile Responsivity

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Pharmacodynamics: Acid-sensing ion channels and Drug Targets

Explores acid-sensing ion channels, drug targets, and ligand-receptor binding.

Drug Target Discovery: Thermal Shift Profiling

Covers drug target discovery through stability shifts and proteomics with isobaric tags.

Drug Targets: Adrenergic Signaling

Explores drug targets and adrenergic signaling, covering receptors, enzymes, and transporter proteins.

Identifying Drug Targets with Thermal-Shift Profiling

Showcases correlations between different organs' thermal profiles to identify drug targets.

Frontiers in Chemical Biology

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Predicting COVID-19 Therapeutic Mechanisms

Explores computational methods to predict COVID-19 therapeutic mechanisms through drug repurposing and machine learning.

Selective Drug Targeting Mechanisms

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The ClpXP Proteolytic Complex: Basic Principles to Drug Discovery

Explores the ClpXP proteolytic complex, its drug targeting potential, and antimicrobial applications through compound screening.

Quantitative Proteome Profiling: Chemical Target Identification

Explores quantitative proteome profiling for drug target identification through activity-based protein profiling and advanced mass spectrometry techniques.

Pharmacology: Transporters & Protein Therapeutics

Explores drug targets, protein therapeutics, and anti-TNF agents in pharmacology.

Parkinson's Disease Drug Development

Explores drug development strategies for Parkinson's Disease, including target identification and potential therapeutic strategies.

General Topics of Pharmacology: Mechanisms and Toxicity

Explores selective targeting in chemotherapy, drug resistance mechanisms, and drug toxicity.

Nuclear Receptors: Drug Targets

Explores nuclear receptors, their role in drug pharmacology, and physiological functions in adipose tissue and glucose homeostasis.

Pharmacodynamics and Drug Targets

Explores pharmacodynamics, drug targets, the renin-angiotensin system, ACE inhibitors, diuretics, and exam questions.

Drug Targets: ligand-gated ion channels and kinase-linked receptors

Explores drug targets in ligand-gated ion channels and kinase-linked receptors, focusing on GABAA receptors, benzodiazepines, and insulin therapy.

Activity-based Protein Profiling: Druggable Sites Identification

Explores Activity-based Protein Profiling for druggable site identification and strategies to minimize off-target reactivity of covalent inhibitors.