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Concept

Biological target

Related lectures (32)

Drug Targets: Receptors, Enzymes, and Transporters

Explores drug targets like receptors, enzymes, and transporters, focusing on top drug indications and receptor-mediated activation of G proteins.

Drug Targets: Receptors, Enzymes, and Therapeutics

Explores drug targets, including receptors, enzymes, and therapeutics, covering pharmacodynamics, case studies on NSAIDs, diabetes, and drug toxicity.

Chemo-proteomics Approaches: Drug-Target Interactions in Cells

Explores protein reactivity, catalysis, and chemical probes in drug-target interactions.

Drug Targets: Ligand-Gated Ion Channels and Kinase-Linked Receptors

Explores drug targets like ligand-gated ion channels and kinase-linked receptors, discussing mechanisms of action, clinical uses, and insulin's physiological context.

Identifying Drug Targets: Safety and Efficacy Log in to Mediaspace to watch this video

Delves into identifying drug targets, ensuring efficacy, and maintaining safety in medical chemistry, covering genetic tests, chirality, stereochemistry, drug resistance, and drug-likeness rules.

Fragment-Based Drug Discovery: Concepts & Technologies Log in to Mediaspace to watch this video

Covers the concepts and technologies of fragment-based drug discovery, hit identification methods, and its application in target-based drug discovery.

Fragment-Based Drug Discovery: Concepts & Technologies Log in to Mediaspace to watch this video

Covers the concepts and technologies of fragment-based drug discovery, exploring hit identification, lead optimization, and screening methods.

Kinase Inhibitors: Types and Mechanisms Log in to Mediaspace to watch this video

Explores kinase inhibitors, enzyme inhibition methods, transition state analog drugs, and the significance of covalent drugs in pharmaceutical research.

Metabolic Pathway Rewiring: Challenges & Insights Log in to Mediaspace to watch this video

Explores metabolomics, the Warburg effect, cell proliferation, and drugs targeting glucose metabolism.

Inhibitor Design & Analysis Log in to Mediaspace to watch this video

Covers the design and analysis of inhibitors for next-generation covalent drugs, focusing on target engagement and the importance of cysteine targeting.

Chemical Biology Fundamentals: Covalent Drug Efficacy Log in to Mediaspace to watch this video

Delves into the efficacy of covalent drugs in chemical biology, exploring reversible vs. irreversible binders and mechanism-based inactivators.

G Protein-Coupled Receptors: Basics and Structures Log in to Mediaspace to watch this video

Explores the basics and structures of G protein-coupled receptors, covering signaling schemes, structures, historical background, drug targeting, and recent advancements.